J-GLOBAL ID:200901004140384961   Update date: Sep. 10, 2019

OGURA Kenichiro

オグラ ケンイチロウ | OGURA Kenichiro
Affiliation and department:
Job title: Associate Professor
Research field  (1): Biological pharmacy
Research keywords  (6): Dihyropyrimidine dehydrogenase ,  UDP-Glucuronosyltransferase ,  SUlfotransferase ,  Drug Metabolizing Enzymes ,  Drug Metabolism ,  Drug Metabolism and Molecular Toxicology
Research theme for competitive and other funds  (1):
  • Study on Structure and Function of Drug Metabolizing Enzymes
Papers (62):
  • Ohnuma T, Sakamoto K, Shinoda A, Takagi C, Ohno S, Nishiyama T, Ogura K, Hiratsuka A. Procyanidins from Cinnamomi Cortex promote proteasome-independent degradation of nuclear Nrf2 through phosphorylation of insulin-like growth factor-1 receptor in A549 cells. Archives of biochemistry and biophysics. 2017. 635. 66-73
  • Ohnuma T, Anzai E, Suzuki Y, Shimoda M, Saito S, Nishiyama T, Ogura K, Hiratsuka A. Selective antagonization of activated Nrf2 and inhibition of cancer cell proliferation by procyanidins from Cinnamomi Cortex extract. Archives of biochemistry and biophysics. 2015. 585. 17-24
  • Yoshida Y, Ogura K, Hiratsuka A, Aisu N, Yamada T, Kojima D, Tanimura S, Ogata K, Hara S, Mogi A, Takamatsu Y, Tamura K, Mishima H, Yamashita Y. 5-Fluorouracil Chemotherapy for Dihydropyrimidine Dehydrogenase-deficient Patients: Potential of the Dose-escalation Method. Anticancer research. 2015. 35. 9. 4881-4887
  • Ogura K, Ishii Y. Significance of non-cytochrome P450 (non-P450) enzymes in basic science, clinical field and drug development. Drug metabolism and pharmacokinetics. 2015. 30. 1. 1-2
  • Nishiyama T, Hayashi N, Kakurai N, Yanagita H, Kuriyama A, Miyamoto C, Ishihara Y, Ogura K, Ohnuma T, Hiratsuka A. Formation and stability of 4-(hydroxymethylnitrosamino)-1-(3-pyridyl)-1-butanone glucuronide, a stable form of reactive intermediate produced from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, in mice. The Journal of toxicological sciences. 2014. 39. 4. 515-521
Education (2):
  • - 1983 Tokyo University of Pharmacy and Life Science Faculty of Pharmaceutical Science
  • - 1986 Tokyo University of Pharmacy and Life Science Graduate School, Division of Pharmaceutical Sciences
Professional career (2):
  • (BLANK)
  • Ph.D. (Tokyo University of Pharmacy and Life Science)
Work history (1):
  • 2007/04 - 現在 Tokyo University of Pharmacy and Life Sciences
Association Membership(s) (1):
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