Kawai Yasushi

カワイヤスシ | Kawai Yasushi

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.nagahama-i-bio.ac.jp/research/%E6%95%99%E5%93%A1%E3%81%AE%E7%B4%B9%E4%BB%8B%EF%BC%88%E6%B2%B3%E5%90%88-%E9%9D%96%EF%BC%89/

Research field (4)： Chemical biology , Functional biochemistry , Bioorganic chemistry , Structural/physical organic chemistry

Research keywords (7)：酵素化学 , Chemical Biology , 反応機構 , 不斉合成 , X線結晶構造解析 , 生物有機化学 , Bioorganic Chemistry

Research theme for competitive and other funds (10)：

2019 - 2022 Development of Induced Fit Off/On Type Fluorescent Probes for the Detection of Disease Related Protein
2015 - 2017 生体関連物質によるoff/on型蛍光プローブの開発とそのガン細胞ターゲティング
2003 - 2004 Absolute Configuration Determination of Chiral Compounds Using a Novel Crystalline Agent
2000 - 2001 Studies on the Novel Enzymatie Reaction Mechanisms Taking into Account the Enzyme Fluctuations
1998 - 1999 酸素を利用した四連続不斉炭素構築反応の開発とその天然物合成への応用

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Papers (105)：

Gengo Kashiwazaki, Ryo Watanabe, Terutaka Tsuzuki, Chieko Yamamoto, Atsuya Nishikawa, Satoru Ohtomo, Tomomi Yoshikawa, Yuto Kitamura, Yoshimi Utaka, Yasushi Kawai, et al. Brønsted acid-induced transannulation of the phytochemical zerumbone. Organic & biomolecular chemistry. 2021. 19. 47. 10444-10454
Yoshimi Utaka, Gengo Kashiwazaki, Noriko Tsuchida, Miyuki Fukushima, Issei Takahashi, Yasushi Kawai, Takashi Kitayama. Remarkable Potential of Zerumbone to Generate a Library with Six Natural Product-like Skeletons by Natural Material-Related Diversity-Oriented Synthesis. The Journal of Organic Chemistry. 2020. 85. 13. 8371-8386
Nuka E, Ohnishi K, Terao J, Kawai Y. ATP/P2X7 receptor signaling as a potential anti-inflammatory target of natural polyphenols. PloS one. 2018. 13. 9. e0204229
Mako Kurogi, Yasushi Kawai, Katsuhiro Nagatomo, Michihiro Tateyama, Yoshihiro Kubo, Osamu Saitoh. Auto-oxidation Products of Epigallocatechin Gallate Activate TRPA1 and TRPV1 in Sensory Neurons. CHEMICAL SENSES. 2015. 40. 1. 27-46
Takashi Kitayama, Maki Nakahira, Kae Yamasaki, Hiromi Inoue, Chika Imada, Yuji Yonekura, Masataka Awata, Hikaru Takaya, Yasushi Kawai, Kohta Ohnishi, et al. Novel synthesis of zerumbone-pendant derivatives and their biological activity. TETRAHEDRON. 2013. 69. 47. 10152-10160

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MISC (83)：

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Patents (8)：

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Education (6)：

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Professional career (1)：

Work history (9)：

2010/10 - 現在 Nagahama Institute of Bio-Science and Technology Faculty of Bio-Science
2004/04 - 2010/09 Nagahama Institute of Bio-Science and Technology Faculty of Bio-Science
1992/04 - 2004/03 Kyoto University Institute for Chemical Research
1992 - 2004 Kyoto University, Instructor
2004 - - Nagahama Institute of Bio-Science and Technology, Associate Professor

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Association Membership(s) (4)：

ケイ素化学協会 , 近畿化学協会 , 日本生化学会 , 日本化学会

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