Rchr
J-GLOBAL ID:200901008093652087
Update date: Jan. 30, 2024
Fukai Shuya
フカイ シユウヤ | Fukai Shuya
Affiliation and department:
Job title:
Professor
Homepage URL (2):
http://kuchem.kyoto-u.ac.jp/kozo/index.html
,
http://kuchem.kyoto-u.ac.jp/kozo/index_en.html
Research field (1):
Structural biochemistry
Research keywords (2):
構造生物化学
, Structural biological chemistry
Research theme for competitive and other funds (18):
- 2018 - 2023 Ubiquitin structural biology providing the molecular basis for chemo-technologies
- 2018 - 2023 New frontier for ubiquitin biology driven by chemo-technologies
- 2018 - 2022 Structural analysis of the epilepsy-related protein complex LGI1-ADAM22-PSD-95 and its regulatory factors
- 2015 - 2018 BRCC36複合体によるK63結合型ユビキチン鎖特異的切断メカニズムの解明
- 2012 - 2016 Structural basis for ubiquitin chain-mediated DNA damage responses
- 2010 - 2016 Structural basis of cell-signaling complexes mediating signal perception, transduction and responses.
- 2010 - 2015 X-ray crystallography of molecular complexes regulating vesicular trafficking
- 2009 - 2011 Structural biology of polyubuiquitin chain recognition
- 2008 - 2009 膜蛋白質のコンフォメーション特異的な結晶化を可能にする抗体断片の開発
- 2008 - 2009 Exocyst複合体の再構成と構造解析
- 2007 - 2008 Structural basis for the activation of Rab GTPases
- 2007 - 2008 Yipタンパク質ファミリーの結晶構造解析
- 2006 - 2007 開口放出で働く繋留因子Exocyst複合体の立体構造解析
- 2005 - 2006 開口放出を制御するタンパク質複合体群の立体構造解析
- 2005 - 2006 X線結晶構造解析に基づく嗅覚・味覚・温覚レセプターの情報変換メカニズムの解明
- 2005 - 2006 分子シャペロンのX線結晶構造解析
- 2005 - 2006 繋留因子群の立体構造解析による膜融合制御機構の解明
- 2004 - 2005 ラットSec6/8複合体の構造・機能解析による,膜融合制御機構の解明
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Papers (85):
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Erika Tsutsumi, Satomi Niwa, Ryota Takeda, Natsuki Sakamoto, Kei Okatsu, Shuya Fukai, Hideo Ago, Satoshi Nagao, Hiroshi Sekiguchi, Kazuki Takeda. Structure of a putative immature form of a Rieske-type iron-sulfur protein in complex with zinc chloride. Communications Chemistry. 2023. 6. 1. 190-190
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Shoun Taguchi, Satomi Niwa, Hoang-Anh Dao, Yoshihiro Tanaka, Ryota Takeda, Shuya Fukai, Kazuya Hasegawa, Kazuki Takeda. Detailed analysis of distorted retinal and its interaction with surrounding residues in the K intermediate of bacteriorhodopsin. Communications Biology. 2023. 6. 1
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Atsushi Yamagata, Yoshiko Murata, Kosuke Namba, Tohru Terada, Shuya Fukai, Mikako Shirouzu. Uptake mechanism of iron-phytosiderophore from the soil based on the structure of yellow stripe transporter. Nature Communications. 2022. 13. 1. 7180-7180
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Takeshi Uemura, Emi Suzuki-Kouyama, Shiori Kawase, Taiga Kurihara, Misato Yasumura, Tomoyuki Yoshida, Shuya Fukai, Maya Yamazaki, Peng Fei, Manabu Abe, et al. Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins. Cell Reports. 2022. 39. 1. 110624-110624
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Norihiko Yokoi, Yuko Fukata, Kei Okatsu, Atsushi Yamagata, Yan Liu, Makoto Sanbo, Yuri Miyazaki, Teppei Goto, Manabu Abe, Hidetoshi Kassai, et al. 14-3-3 proteins stabilize LGI1-ADAM22 levels to regulate seizure thresholds in mice. Cell Reports. 2021. 37. 11. 110107-110107
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MISC (16):
Lectures and oral presentations (35):
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Identification of Peptidic Inhibitors Targeting p97-hUfd1-hNpl4 Complex
(日本薬学会年会要旨集(Web) 2022)
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炎症シグナルタンパク質TAB2のNZFドメインによるK6結合型ユビキチン鎖認識の構造基盤
(日本蛋白質科学会年会プログラム・要旨集 2022)
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ケモテクノロジーが拓くユビキチンニューフロンティア ヒトDUBアレイ技術を用いたUSP特異的阻害剤の開発
(日本生化学会大会プログラム・講演要旨集 2020)
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ユビキチンリガーゼUBE3Aは26Sプロテアソームの負の調節因子である
(日本分子生物学会年会プログラム・要旨集(Web) 2020)
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PINK1 activation by its unconventional localization to the outer mitochondrial membrane
(日本分子生物学会年会プログラム・要旨集(Web) 2019)
more...
Education (2):
- - 2002 The University of Tokyo
- - 1997 The University of Tokyo Faculty of Science Department of Biophysics and Biochemistry
Professional career (1):
- Doctor of Science (The University of Tokyo)
Work history (7):
- 2020/03 - 現在 Kyoto University Department of Chemistry, Graduate School of Science Professor
- 2018/04 - 2020/02 The University of Tokyo Institute for Quantitative Biosciences Associate Professor
- 2016/12 - 2018/03 The University of Tokyo Institute of Molecular and Cellular Biosciences Associate Professor
- 2007/05 - 2016/11 The University of Tokyo Organization for Synchrotron Radiation Research Associate Professor
- 2006/04 - 2007/05 Tokyo Institute of Technology Center for Biological Resources and Informatics Associate Professor
- 2003/06 - 2006/03 Tokyo Institute of Technology Graduate School of Bioscience and Biotechnology, Department of Biological Information Research Associate
- 2002/04 - 2003/07 Stanford University School of Medicine Department of Molecular and Cellular Physiology JSPS Postdoctoral Fellow for Research Abroad
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