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J-GLOBAL ID：202002286367037929   Reference number：20A0331218

Insights into the mechanisms of epilepsy from structural biology of LGI1-ADAM22

LGI1-ADAM22の構造生物学からのてんかん機構への洞察【JST・京大機械翻訳】

Author (7)： Yamagata Atsushi (Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan) ,  Yamagata Atsushi (Synchrotron Radiation Research Organization, The University of Tokyo, Tokyo, Japan) ,  Yamagata Atsushi (Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan) ,  Yamagata Atsushi (Laboratory for Protein Functional and Structural Biology, RIKEN Center for Biosystems Dynamics Research, Yokohama, Kanagawa, Japan) ,  Fukai Shuya (Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan) ,  Fukai Shuya (Synchrotron Radiation Research Organization, The University of Tokyo, Tokyo, Japan) ,  Fukai Shuya (Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan)
Material： Cellular and Molecular Life Sciences
Volume： 77  Issue： 2  Page： 267-274  Publication year： 2020 
JST Material Number： B0496A  ISSN： 1420-682X  CODEN： CMLSFI  Document type： Article
Article type： 文献レビュー  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Abstract/Point： Abstract: Epilepsy is one of t...

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Thesaurus term： pathogenicity ,  synapse ,  seizure (disease) ,  Ion Channels ,  dominance ,  glioma ,  autoantibody ,  *Epilepsy ,  pathogenesis ,  anticonvulsant ,  neuron ,  Heredity ,  autosome ,  Mutation ,  secretory protein ,  Ion Transport ,  transportation ,  Biological Transport ,  transmembrane protein ,  ion transport(in vivo) ,  nervinum ,  central nervous system drug ,  central nervous system depressant

Author keywords (6)： Epilepsy ,  LGI1 ,  ADAM22 ,  Synapse ,  Autoantibody ,  Chemical corrector

JST classification (2)： Biological function  (EB03040U) ,  Nervous system in general  (EJ12010J)

Terms in the title (5)： LGI1 ,  ADAM22 ,  構造生物学 ,  てんかん ,  洞察