Rchr
J-GLOBAL ID：200901011860536315
Update date: Feb. 14, 2024
Mashima Keisuke
Mashima Keisuke
Affiliation and department：
Rikkyo University College of Science Department of Life Science
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Detailed information
Job title：
Professor
Other affiliations (2)：
理学研究科
生命理学専攻博士課程前期課程 教授
Graduate School of Science
Field of Study: Life Science Professor
Research field (2)：
Immunology
, Functional biochemistry
Research keywords (3)：
リン酸化・脱リン酸化
, signal transduction
, Protein tyrosine phosphatase
Research theme for competitive and other funds (7)：
1999 - 2000 ウニの初期胚発生におけるタンパク質チロシン残基のリン酸化・脱リン酸化の機能解析
1996 - 1997 免疫担当細胞であるBリンパ球で発現している受容体型チロシンホスファターゼCD45と特異的に結合するリガンドの同定とその構造解析
1994 - 1996 骨髄性白血病細胞のタンパク質チロシンホスファターゼ(PTP)の多様性と機能に関する研究
1991 - 1992 細胞の癌化における チロシンホスファターゼの役割に関する研究
1991 - 1992 細胞の癌化及び分化におけるチロシン残基のリン酸化反応・脱リン酸化反応の役割に関する研究
A study of protein tyrosine phosphatase on signal transduction.
チロシンホスファターゼによる細胞内情報伝達の制御機構
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Papers (33)：
Matsuoka, H, Harada, K, Mashima, K, Inoue, M. Muscarinic receptor stimulation induces TASK1 channel endocytosis through a PKC-Pyk2-Src pathway in PC12 cells. Cellular signaling. 2020. 65. 109434
Makino, R, Obata, Y, Tsubaki, M, Iizuka, T, Hamajima, Y, Kato-Yamada, Y, Mashima, K, Shiro, Y. Mechanistic Insights into the Activation of Soluble Guanylate Cyclase by Carbon Monoxide: A Multi-Step Mechanism Proposed for the BAY 41-2272-Induced Formation of 5-Coordinate CO-Heme. Biochemistry. 2018. 57. 10. 1620-1631
Makino, R, Obayashi, E, Hori, H, Iizuka, T, Mashima, K, Shiro, Y, Ishimura, Y. The Initial O2 Inserting Step of Tryptophan Dioxygenase Reaction Proposed by a Heme-Modification Study. Biochemistry. 2015. 54. 3604-3616
Motohashi, S, Koizumi, K, Honda, R, Maruyama, A, Palmer, E.F. H, Mashima, K. Protein tyrosine phosphatase-PEST (PTP-PEST) regulates mast cell-activating signals in PTP activity-dependent and -independent manners. Cell Immunol. 2014. 287. 128-134
Nakamura, K, Palmer, E.E.H, Ozawa, T, Mashima, K. Protein Phosphatase 1alpha Associates to Protein Tyrosine Phosphatase-PEST inducing dephosphorylation of phospho-Serine 39. 2010
ｍore...
Education (3)：
- 1987 Osaka University Graduate School, Division of Natural Science
- 1984 Osaka University Graduate School, Division of Natural Science
- 1981 University of Tsukuba Second Cluster of College
Professional career (2)：
理学博士
理学博士 (大阪大学)
Work history (9)：
2010/04/01 - 現在 RIKKYO UNIVERSITY Graduate School of Science Field of Study: Life Science Professor
2010/04/01 - 現在 RIKKYO UNIVERSITY Graduate School of Science Field of Study: Life Science Professor
2010/04/01 - 現在 RIKKYO UNIVERSITY College of Science Department of Life Science Professor
2007/04/01 - 2010/03/31 RIKKYO UNIVERSITY College of Science Department of Life Science Associate Professor
2002/04/01 - 2007/03/31 RIKKYO UNIVERSITY College of Science Department of Life Science Associate Professor (as old post name)
1997/04/01 - 2002/03/31 RIKKYO UNIVERSITY College of Science Department of Chemistry Associate Professor (as old post name)
1995/04/01 - 1997/03/31 RIKKYO UNIVERSITY College of Science Department of Chemistry Lecturer
1989/04/01 - 1995/03/31 RIKKYO UNIVERSITY College of Science Department of Chemistry Full-time Research Assistant
1987/06/01 - 1988/06/30 岡崎国立共同研究機構・基礎生物学研究所 講師(PD相当)
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