Takagi Toshiyuki

タカギトシユキ | Takagi Toshiyuki

Affiliation and department：
Job title：主任研究員
Homepage URL (1)： http://www.aist.go.jp/RESEARCHERDB/cgi-bin/worker_detail.cgi?call=namae&rw_id=T84972279

Research field (7)： Pharmaceuticals - chemistry and drug development , Polymer materials , Electronic devices and equipment , Bioorganic chemistry , Structural/physical organic chemistry , Nanobioscience , Nanomaterials

Research keywords (3)：フッ素化合物脂質ナノバイオ材料光機能材料電磁波癌治療材料 , global warming , fluorine compound

Research theme for competitive and other funds (12)：

2020 - 2023 フルオロフォビック効果による自発的膜タンパク質集積を用いた人工細胞膜構造体の創製
2019 - 2022 バイオシステムの多様な光制御を実現する新規機能性ポリマーの光応答物性
2018 - 2021 Development of partially fluorinated lipid/membrane protein complex designed based on Stratified Dipole-Arrays model
2016 - 2019 Photolithographic fabrication of flexible and wet semi 3-D microstructure and its application to novel biochip
2015 - 2018 Development of fluorinated fluorescent probes for membrane protein reconstitution matrices

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Papers (105)：

Takeshi Hasegawa, Ai Nakagawara, Toshiyuki Takagi, Takafumi Shimoaka, Nobutaka Shioya, Masashi Sonoyama. Phonon modes controlled by primary chemical structure of partially fluorinated dimyristoylphosphatidylcholine (DMPC) revealed by multiple-angle incidence resolution spectrometry (MAIRS). The Journal of Chemical Physics. 2024. 160. 064704
Masaya Miyazaki, Chika Arisaka, Ai Nakagawara, Nanako Sasaki, Hiroshi Takahashi, Toshiyuki Takagi, Hideki Amii, Masashi Sonoyama. Thermodynamic study on hydrated bilayers of ether-linked phosphatidylcholines with terminal perfluorobutyl group. Biochimica et Biophysica Acta (BBA) - Biomembranes. 2024. 1866. 2. 184261-184261
Masayuki Sano, Kana Morishita, Yuri Onizawa, Toshiyuki Takagi, Kimio Sumaru. Rapid and Highly Sensitive Method for Evaluating Surface Coatings against an Enveloped RNA Virus. ACS applied bio materials. 2022
Mami Hashimoto, Yuka Murai, Kohei Morita, Takashi Kikukawa, Toshiyuki Takagi, Hiroshi Takahashi, Yasunori Yokoyama, Hideki Amii, Masashi Sonoyama. Comparison of functionality and structural stability of bacteriorhodopsin reconstituted in partially fluorinated dimyristoylphosphatidylcholine liposomes with different perfluoroalkyl chain lengths. Biochimica et Biophysica Acta (BBA) - Biomembranes. 2021. 1863. 10. 183686-183686
Naoyuki Tsuchida, Toshiyuki Takagi, Hiroshi Takahashi, Toshitada Yoshihara, Seiji Tobita, Masashi Sonoyama. Membrane properties of amacrocyclic tetraether bisphosphatidylcholine lipid: Effect of a single membrane-spanning polymethylene cross-linkage between two head groups of ditetradecylphosphatidylcholine membrane. Biochimica et biophysica acta. Biomembranes. 2021. 1863. 5. 183569-183569

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MISC (391)：

土田直之, 高木俊之, 高橋浩, 吉原利忠, 飛田成史, 園山正史, 園山正史, 園山正史. Membrane Properties and Molecular Packing of Amacrocyclic Ether-Linked Phospholipid. KEK Progress Report (Web). 2021. 2021-4
須丸公雄, 高木俊之, 金森敏幸. Photoregulation of Biomaterials Functions: Novel Photoresponsive Polymer Materials Implementing On-demand Cell Manipulation. バイオマテリアル(Web). 2019. 37. 3
須丸公雄, 高木俊之, 森下加奈, 金森敏幸. 光水溶化ポリマー膜を用いた半立体細胞組織体形成. 膜シンポジウム. 2019. 31
高橋浩, 吉野賢, 森田康平, 高木俊之, 横山泰範, 菊川峰志, 網井秀樹, 金森敏幸, 園山正史, 園山正史, et al. 部分フッ素化リン脂質F4-DMPC膜に再構成した膜タンパク質バクテリオロドプシンの2次元格子の安定性. KEK Progress Report (Web). 2019. 2019-7
川原るい, 高木俊之, 高橋浩, 菊川峰志, 網井秀樹, 園山正史, 園山正史, 園山正史. 擬環状エーテル型脂質のフッ素化が膜物性および膜タンパク質の構造・機能に及ぼす影響. フッ素化学討論会講演要旨集. 2019. 42nd

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Patents (59)：

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Books (3)：

アクチュエータの新材料,駆動制御,最新応用技術
技術情報協会 2017 ISBN:9784861046490
ゲルテクノロジーハンドブック-機能設計・評価・シミュレーションから製造プロセス・製品化まで
エヌティーエス 2014 ISBN:486469074X
Soft actuators : materials, modeling, applications, and future perspectives
Springer 2014 ISBN:9784431547662

Works (2)：

2) 「SF6等に代替するガスを利用した電子デバイス製造クリーニングシステムの研究開発」,(財)地球環境産業技術研究機構,
1998 - 2002
1) 「エネルギー使用合理化新規冷媒等研究開発」,(財)地球環境産業技術研究機構
1997 - 1999

Professional career (1)：

Ph. D. in Pharmacy

Association Membership(s) (8)：

日本DDS学会 , 高分子化学会 , 有機合成化学協会 , 日本薬学会 , 日本化学会 , The Pharmaceutical Society of Japan , Journal of Synthetic Organic Chemistry Japan , Chemical Society of Japan

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