Rchr
J-GLOBAL ID:200901013349394874   Update date: Jan. 02, 2023

Hirabayashi Yoko

ヒラバヤシ ヨウコ | Hirabayashi Yoko
Affiliation and department:
Job title: Director
Research field  (3): Experimental pathology ,  Environmental effects of chemicals ,  Environmental effects of radiation
Research keywords  (8): Hematopathology ,  Molecular Toxicology ,  細胞周期 ,  生体異物相互作用 ,  造血幹細胞 ,  Cell cycle ,  Xenobiotic response ,  Hematopoietic stem cell
Research theme for competitive and other funds  (16):
  • 2009 - 2011 Toxicity mechanism in hematopoietic stem/progenitor-derived signaling via aryl hydrocarbon receptors induced by benzene exposure
  • 2008 - 2011 Mechanism underlying functional impairment of hematopoietic stem cell niches caused by oxidative stress at the site of xenobiotic interrelationship
  • 2006 - 2008 Biological function of aryl hydrocarbon receptors in the hematopoietic progenitor cells with respect to a possible toxicologic mechanism
  • 2004 - 2006 Oxidative stress-related xenobiotic responsive molecule : Study using mice with modified thioredoxin gene expression.
  • 2003 - 2005 Mechanism of benzene-induced hematopoietic disturbances mediated by arylhydrocarbon receptors
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Papers (70):
  • Yusuke Okubo, Fumiaki Ohtake, Katsuhide Igarashi, Yukuto Yasuhiko, Yoko Hirabayashi, Yumiko Saga, Jun Kanno. Cleaved Delta like 1 intracellular domain regulates neural development via Notch signal dependent and independent pathways. Development (Cambridge, England). 2021
  • Eiichi Yamamoto, Yuhji Taquahashi, Makiko Kuwagata, Hirokatsu Saito, Kohei Matsushita, Takeshi Toyoda, Futoshi Sato, Satoshi Kitajima, Kumiko Ogawa, Ken-Ichi Izutsu, et al. Visualizing the spatial localization of ciclesonide and its metabolites in rat lungs after inhalation of 1-μm aerosol of ciclesonide by desorption electrospray ionization-time of flight mass spectrometry imaging. International journal of pharmaceutics. 2021. 595. 120241-120241
  • Ryuichi Ono, Yusuke Yoshioka, Yusuke Furukawa, Mie Naruse, Makiko Kuwagata, Takahiro Ochiya, Satoshi Kitajima, Yoko Hirabayashi. Novel hepatotoxicity biomarkers of extracellular vesicle (EV)-associated miRNAs induced by CCl4. Toxicology reports. 2020. 7. 685-692
  • Ryuichi Ono, Yusuke Yoshioka, Yusuke Furukawa, Mie Naruse, Makiko Kuwagata, Takahiro Ochiya, Satoshi Kitajima, Yoko Hirabayashi. Novel hepatotoxicity biomarkers of extracellular vesicle (EV)-associated miRNAs induced by CCl4. Toxicology Reports. 2020. 7. 685-692
  • Shin-Ichi Oka, Adave Chin, Ji Yeon Park, Shohei Ikeda, Wataru Mizushima, Guersom Ralda, Peiyong Zhai, Mingming Tong, Jaemin Byun, Fan Tang, et al. Thioredoxin-1 maintains mitochondrial function via mTOR signaling in the heart. Cardiovascular research. 2019. 116. 10. 1742-1755
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MISC (14):
  • Yukuto Yasuhiko, Yoko Hirabayashi, Ryuichi Ono. Tbx6 regulates gene expression via binding sites in Long Terminal Repeats (LTR) of endogenous retrovirus during mouse embryogenesis. MECHANISMS OF DEVELOPMENT. 2017. 145. S112-S113
  • Yoko Hirabayashi. Radiation-induced, cell cycle-related gene expression in aging hematopoietic stem cells: enigma of their recovery. Annals of the New York Academy of Sciences. 2014. 1310. 69-73
  • Yoko Hirabayashi, Isao Tsuboi, Byung-Il Yoon, Jun Kanno, James Trosko, Tohru Inoue. Role Of Connexin 32 In Hematopoiesis: Maintaining Quiescence Of Hematopoietic Stem Cells and Their Proliferation. BLOOD. 2013. 122. 21
  • Yoko Hirabayashi, Byung-IL Yoon, Isao Tsuboi, Jun Kanno, James Trosko, Tohru Inoue. ROLE OF CONNEXIN 32: MAINTENANCE OF CELL QUIESCENCE AND SUPPORT OF PROLIFERATION OF HEMATOPOIETIC STEM/PROGENITOR CELLS. EXPERIMENTAL HEMATOLOGY. 2012. 40. 8. S126-S127
  • Y. Hirabayashi, B. I. Yoon, K. Igarashi, Y. Kodama, K. Sekita, T. Kaneko, J. Kanno, T. Inoue. Strain differences of the effect of benzene exposure: Microarray study of the bone marrow in C57BL/6 and C3H/He mice. TOXICOLOGY LETTERS. 2010. 196. S175-S175
more...
Education (2):
  • 1986 - 1991 Yokohama City University Graduate School for Medical Science Pathology & Molecular Hematology
  • 1980 - 1986 Yokohama City University School of Medicine
Professional career (1):
  • MD (Yokohama City University, School of Medicine)
Committee career (2):
  • 2021/05 - 現在 日本動物実験代替法学会 代議員
  • 2020/07 - 現在 日本実験動物学会 評議員
Association Membership(s) (14):
The Japanese Society for Anternatives to Animal Experiments ,  JAPANESE SOCIETY FOR FOOD HYGIENE AND SAFETY ,  日本実験動物学会 ,  Japanese Society of Food Chemistry ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY OF TOXICOLOGIC PATHOLOGY ,  Society of Toxicology ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  THE JAPANESE SOCIETY OF HEMATOLOGY ,  THE JAPANESE CANCER ASSOCIATION ,  THE JAPANESE SOCIETY OF TOXICOLOGY ,  International Society for Stem Cell Research ,  American Society of Hematology ,  THE JAPANESE SOCIETY OF PATHOLOGY
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