Nakatani Sachie

ナカタニサチエ | Nakatani Sachie

Affiliation and department：
Job title： Assistant Professor
Homepage URL (1)： https://www.josai.ac.jp/education/pharmacy/pharm4_dep/laboratory/kinouseisyokuhin.html

Research field (4)： Nutrition and health science , Pharmaceuticals - health and biochemistry , Cell biology , Applied biochemistry

Research keywords (6)： Osteoporosis , Mesenchymal stem cell , 変形性関節症 , 軟骨 , DNAマイクロアレイ , 機能性食品

Research theme for competitive and other funds (8)：

2022 - 2025 Mesenchymal stem cell-targeted bioactive peptides for simultaneous prevention of osteoporosis and obesity.
2017 - 2021 Regulatory mechanism of chondrogenic differentiation by collagen-derived bioactive peptides
2013 - 2015 The effect of collagen degradation products on cartilage metabolism.
2013 - 2014 とかちABCプロジェクト
2012 - 2013 ザクロエキスの抗糖化作用の検討

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Papers (16)：

Tomoharu Takeuchi, Yasuhiro Horimoto, Midori Oyama, Sachie Nakatani, Kenji Kobata, Mayumi Tamura, Yoichiro Arata, Tomomi Hatanaka. Osteoclast differentiation is suppressed by increased O-GlcNAcylation due to thiamet G treatment. Biological and Pharmaceutical Bulletin. 2020. 43. 10. 1501-1505
Giichirou Nakaya, Hiroshi Sakagami, Yukari Koga-Ogawa, Akiyoshi Shiroto, Tadamasa Nobesawa, Daisuke Ueda, Sachie Nakatani, Kenji Kobata, Yosuke Iijima, Shigenobu Tone, et al. Augmentation of neurotoxicity of anticancer drugs by X-ray irradiation. In Vivo. 2020. 34. 3. 1009-1016
ANGEL DAVID PAULINO-GONZALEZ, HIROSHI SAKAGAMI, KENJIRO BANDOW, YUMIKO KANDA, YUKO NAGASAWA, YASUSHI HIBINO, HIROSHI NAKAJIMA, SATOSHI YOKOSE, OSAMU AMANO, GIICHIROU NAKAYA, et al. Biological Properties of the Aggregated Form of Chitosan Magnetic Nanoparticle. In Vivo. 2020. 34. 4. 1729-1738
Yoshifumi Kimira, Masafumi Saito, Seiji Kushibe, Kaho Nomura, Yoshihiro Osawa, Yusuke Sekiguchi, Jun Shimizu, Sachie Nakatani, Seiko Koizumi, Naoki Inoue, et al. The effects of collagen peptide supplementation on knee joint health: a double-blind, placebo-controlled, randomized trial in healthy university students belonging to a running club. Jpn Pharmacol Ther. 2019. 47. 9. 1455-1462
Toshiya Kudo, Sachie Nakatani, Misato Kakizaki, Ai Arai, Keisuke Ishida, Masahiro Wada, Kenji Kobata. Supplemented Chondroitin Sulfate and Hyaluronic Acid Suppress Mineralization of the Chondrogenic Cell Line, ATDC5, via Direct Inhibition of Alkaline Phosphatase. BIOLOGICAL & PHARMACEUTICAL BULLETIN. 2017. 40. 12. 2075-2080

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MISC (33)：

Effect of glucosamine on osteoblast cell proliferation and osteoclast differentiation. 2012. 18. 1. 54-57
Oral Administration of N-acetyl glucosamine Affects Bone Mineral Density in C57BL/6J Mice. 2011. 7. 51-56
SHIMIZU Tatsuo, NAKATANI Sachie, MANO Hiroshi, KOBATA Kenji, WADA Masahiro. Effect of N-acetyl-D-glucosamine on osteoblasts and osteoclasts. 2011. 17. 2. 243-243
SHIMIZU Tatsuo, NAKATANI Sachie, KOBATA Kenji, WADA Masahiro. Oral administration of N-acetyl-D-glucosamine and D-glucosamine hydrochloride affects bone mineral density in C57BL/6J mice. Chitin and chitosan research. 2011. 17. 1. 74-78
田島彩沙, 池口文彦, 齋田麻実, 中谷祥恵, 平澤恵理, 石島旨章, 和田政裕, 真野博, 白幡晶. スペルミン合成酵素遺伝子改変マウスにおける骨代謝・軟骨代謝異常の解析. 日本薬学会年会要旨集. 2011. 131年会. 3. 161-161

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Patents (2)：

COLLAGEN PEPTIDE, DIPEPIDE, AND AGENT FOR PREVENTATION DESEASE
関節軟骨促進剤

Books (1)：

Handbook of Biochip Techinology バイオチップ実用化ハンドブック
(株)エヌ・ティー・エス出版 2010

Lectures and oral presentations (26)：

Chondroprotective effect of the bioactive peptide prolyl-hydroxyproline in mouse articular cartilage in vitro and in vivo.
(第32回日本分子生物学会年会 2009)
グルコサミン塩酸塩およびN-アセチルグルコサミンの摂取がマウス皮膚組織に与える影響
(第23回キチン・キトサンシンポジウム 2009)
The leaf of Kothala himbutu (Salacia reticulata) improved the damage in cartilage and bone tissues on the symptom of rheumatoid arthritis
(4th International Niigata Syposium on Diet and Health 2008)
グルコサミンがマウス骨代謝に与える影響
(第22回キチン・キトサンシンポジウム 2008)
グルコサミンがマウス硬組織に与える影響
(第62回日本栄養・食糧学会大会 2008)

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Education (3)：

2004 - 2007 Graduate school of josai university Graduate School, Division of Pharmaceutical Sciences
2002 - 2004 Graduate school of Josai University Graduate School, Division of Pharmaceutical Sciences
1998 - 2002 Tokyo University of Agriculture Faculty of Applied Bio-Science Department of Bio-Science

Professional career (1)：

Ph.D. (Josai University)

Work history (2)：

2013/04 - 現在 Josai University Faculty of Pharmaceutical Sciences
2007/04 - 2013/03 Josai University Faculty of Pharmaceutical Sciences

Committee career (1)：

平成22年度~23年度日本キチン・キトサン学会理事

Association Membership(s) (7)：

日本キチン・キトサン学会 , 日本薬学会 , 日本栄養・食糧学会 , 日本分子生物学会 , The Pharmaceutical Society of Japan , The Japanese Society of Nutrition and Food Science , The Molecular Biology Society of Japan

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