Rchr
J-GLOBAL ID:200901017150818697   Update date: Jul. 06, 2020

Kakuta Hiroki

カクタ ヒロキ | Kakuta Hiroki
Affiliation and department:
Job title: Associate Professor
Homepage URL  (2): http://www.cc.okayama-u.ac.jp/~kakuta-h/kakuta_lab/index.htmlhttp://www.cc.okayama-u.ac.jp/~kakuta-h/kakuta_lab_english/index.html
Research field  (2): Biochemistry ,  Pharmaceuticals - chemistry and drug development
Research keywords  (8): Medicinal chemistry ,  Boron Neutron Capture Therapy ,  physiologically active substance ,  nucear receptor ,  anti-inflammatory drug ,  differentiation inducer ,  antitumor drug ,  retinoids
Papers (39):
  • Yamada S, Kawasaki M, Fujihara M, Watanabe M, Takamura Y, Takioku M, Nishioka H, Takeuchi Y, Makishima M, Motoyama T, Ito S, Tokiwa H, Nakano S, Kakuta H. Competitive Binding Assay with an Umbelliferone-based Fluorescent Rexinoid for Retinoid X Receptor Ligand Screening. Journal of medicinal chemistry. 2019
  • Takamura Y, Takahashi M, Nishii M, Shibahara O, Watanabe M, Fujihara M, Kakuta H. 3H-Imidazo[4,5-b]pyridine-6-carboxylic acid derivatives as rexinoids with reduced teratogenicity. Bioorganic & medicinal chemistry letters. 2019. 29. 15. 1891-1894
  • Takamura Y, Shibahara O, Watanabe M, Fujihara M, Yamada S, Akehi M, Sasaki T, Hirano H, Kakuta H. Fluorine-18 (18F)-labeled retinoid x receptor (RXR) partial agonist whose tissue transferability is affected by other RXR ligands. Bioorganic & medicinal chemistry. 2019. 27. 14. 3128-3134
  • Shibahara O, Watanabe M, Takamura Y, Yamada S, Akehi M, Sasaki T, Akahoshi A, Hanada T, Hirano H, Nakatani S, Nishioka H, Takeuchi Y, Kakuta H. Correction to Synthesis of 11C-Labeled RXR Partial Agonist 1-[(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)amino]benzotriazole-5-carboxylic Acid (CBt-PMN) by Direct [11C]Carbon Dioxide Fixation via Organolithiation of Tri. Journal of medicinal chemistry. 2019. 62. 9. 4780-4781
  • Itaba N, Kono Y, Watanabe K, Yokobata T, Oka H, Osaki M, Kakuta H, Morimoto M, Shiota G. Reversal of established liver fibrosis by IC-2-engineered mesenchymal stem cell sheets. Scientific reports. 2019. 9. 1. 6841
more...
MISC (86):
Education (4):
  • - 2003 The University of Tokyo Graduate School, Division of Pharmaceutical Sciences
  • - 2003 The University of Tokyo Graduate School, Division of Pharmaceutical Sciences
  • - 1997 Okayama University Faculty of Pharmaceutical Sciences
  • - 1997 Okayama University Faculty of Pharmaceutical Science
Professional career (1):
  • Ph.D.
Work history (5):
  • 2007 - 2008 Assistant Professor,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University
  • 2008 - - Associate Professor,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University
  • 2004 - 2007 Research Associate,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University
  • 2003 - 2004 Okayama University
  • 2003 - 2004 Research Associate,Faculty of Pharmaceutical Sciences,Okayama University
Awards (3):
  • 2015/07 - Okayama Foundation for Science and Technology Science and Technology Award in Okayama Foundation of Science and Technology
  • 2012/02 - Okayama University 2011 Young Top Researcher Award
  • 2010/11 - Award for Excellent General Presentation in the Medicinal Chemistry Symposium
Association Membership(s) (3):
THE PHARMACEUTICAL SOCIETY OF JAPAN ,  American chemical society ,  The Vitamin Society of Japan
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