Tsuge Kenji

ツゲケンジ | Tsuge Kenji

Affiliation and department：
Job title： Guest Associate Professor

Research field (1)： Systems genomics

Research theme for competitive and other funds (6)：

2016 - 2018 化学修飾DNAを用いた新規枯草菌形質転換法の確立
2017 - 【NEDO:三菱ケミカル】共同研究員受入
2011 - 2016 Construction of artificial metabolic pathway that is comprised of multiple genes
2011 - 2016 Synthetic Biology for the Comprehension of Biomolecular Networks
2009 - 2010 Study on an operon rule toward designing of artificial operon

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Papers (42)：

Varada Jagadeesh, Nobuyuki Okahashi, Fumio Matsuda, Kenji Tsuge, Akihiko Kondo. Combinatorial Nonribosomal Peptide Synthetase Libraries Using the SEAM-Combi-OGAB Method. ACS synthetic biology. 2025. 14. 2. 520-530
Musashi Takekana, Takanobu Yoshida, Erika Yoshida, Sumika Ono, Shinnosuke Horie, Christopher J. Vavricka, Moe Hiratani, Kenji Tsuge, Jun Ishii, Yoshihiro Hayakawa, et al. Online SFE-SFC-MS/MS colony screening: A high-throughput approach for optimizing (-)-limonene production. Journal of Chromatography B. 2023. 1215. 123588-123588
Varada Jagadeesh, Takanobu Yoshida, Misugi Uraji, Nobuyuki Okahashi, Fumio Matsuda, Christopher J. Vavricka, Kenji Tsuge, Akihiko Kondo. Simple and Rapid Non-ribosomal Peptide Synthetase Gene Assembly Using the SEAM-OGAB Method. ACS Synthetic Biology. 2022. 12. 1. 305-318
Christopher J. Vavricka, Shunsuke Takahashi, Naoki Watanabe, Musashi Takenaka, Mami Matsuda, Takanobu Yoshida, Ryo Suzuki, Hiromasa Kiyota, Jianyong Li, Hiromichi Minami, et al. Machine learning discovery of missing links that mediate alternative branches to plant alkaloids. Nature Communications. 2022. 13. 1. 1405
Christopher J. Vavricka, Takanobu Yoshida, Yuki Kuriya, Shunsuke Takahashi, Teppei Ogawa, Fumie Ono, Kazuko Agari, Hiromasa Kiyota, Jianyong Li, Jun Ishii, et al. Mechanism-based tuning of insect 3,4-dihydroxyphenylacetaldehyde synthase for synthetic bioproduction of benzylisoquinoline alkaloids. Nature Communications. 2019. 10. 1

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MISC (33)：

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Books (8)：

スマートセルインダストリー -微生物細胞を用いた物質生産の展望-, 第1編ハイスループット合成・分析・評価技術, 第1章ハイスループット長鎖DNA合成技術:「OGAB法による長鎖DNA合成技術」
シーエムシー出版 2018
Microbial Production, Chapter 4. Efficient and accurate production of de novo designed large-size gene clusters by a novel Bacillus subtilis-based system
Springer 2014
ひらく、ひらく「バイオの世界」14歳からの生物工学入門
化学同人 2012
合成生物工学の隆起-有用物質の新たな生産法構築をめざして-, 第1章ゲノムからの視点「ゲノム再構築技術の応用と課題:汎用性,迅速性,コスト」
シーエムシー出版 2012
Escherichia coli and Bacillus subtilis; the frontiers of molecular microbiology revisited, Chapter 9. Genome integrity, instability and construction
Research Signpost 2012

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Lectures and oral presentations (74)：

長鎖DNA合成
(2019年度第2回NEDOスマートセルプロジェクト技術セミナー 2019)
Long chain DNA foundry at Kobe University
(2019 GP-W & Sc2.0 Meeting 2019)
Development of total system for long-chain DNA synthesis by OGAB method
(2019 Asian Synthetic Biology Association (ASBA) Meeting 2019)
光駆動ATP再生系による出芽酵母型Vmax細胞の創製
(酵母遺伝学フォーラム第52回研究報告会 2019)
ロドプシンを利用した大腸菌における光駆動ATP再生の物質生産への応用
(第71回日本生物工学会大会 2019)

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Education (1)：

- 1998 Tokyo Institute of Technology Graduate School, Division of Integrated Science and Engineering 化学環境工学専攻

Professional career (2)：

Work history (3)：

2020/04 - 現在 Kobe University Graduate School of Science, Technology and Innovation
2016/04 - 2020/03 Kobe University Graduate School of Science, Technology and Innovation
Keio University Graduate School of Media and Governance, Major in Media and Governance Project Senior Assistant Professor / Project Assistant Professor / Project Lecturer

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