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J-GLOBAL ID：201902228024953910   Reference number：19A0849125

Heterologous production of free dihomo-γ-linolenic acid by Aspergillus oryzae and its extracellular release via surfactant supplementation

Aspergillus oryzaeによる遊離ジホモ-γ-リノレン酸の異種生産と界面活性剤添加によるその菌体外放出

Author (13)： Tamano Koichi (Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 2-17-2-1 Tsukisamu-Higashi, Toyohira-ku, Sapporo, Hokkaido 062-8517, Japan) ,  Cox Robert Sidney (Graduate School of Science, Technology and Innovation, Kobe University, 1-1 Rokkodai, Nada, Kobe, Hyogo 657-8501, Japan) ,  Tsuge Kenji (Graduate School of Science, Technology and Innovation, Kobe University, 1-1 Rokkodai, Nada, Kobe, Hyogo 657-8501, Japan) ,  Tsuge Kenji (Engineering Biology Research Center, Kobe University, 1-1 Rokkodai, Nada, Kobe, Hyogo 657-8501, Japan) ,  Miura Ai (Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 2-17-2-1 Tsukisamu-Higashi, Toyohira-ku, Sapporo, Hokkaido 062-8517, Japan) ,  Itoh Ayano (Hokkaido High-Technology College, 2-12-1 Meguminokita, Eniwa, Hokkaido 061-1396, Japan) ,  Ishii Jun (Graduate School of Science, Technology and Innovation, Kobe University, 1-1 Rokkodai, Nada, Kobe, Hyogo 657-8501, Japan) ,  Ishii Jun (Engineering Biology Research Center, Kobe University, 1-1 Rokkodai, Nada, Kobe, Hyogo 657-8501, Japan) ,  Tamura Tomohiro (Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 2-17-2-1 Tsukisamu-Higashi, Toyohira-ku, Sapporo, Hokkaido 062-8517, Japan) ,  Tamura Tomohiro (Computational Bio Big Data Open Innovation Laboratory (CBBD-OIL), National Institute of Advanced Industrial Science and Technology (AIST), 2-17-2-1 Tsukisamu-Higashi, Toyohira-ku, Sapporo, Hokkaido 062-8517, Japan) ,  Kondo Akihiko (Graduate School of Science, Technology and Innovation, Kobe University, 1-1 Rokkodai, Nada, Kobe, Hyogo 657-8501, Japan) ,  Kondo Akihiko (Engineering Biology Research Center, Kobe University, 1-1 Rokkodai, Nada, Kobe, Hyogo 657-8501, Japan) ,  Machida Masayuki (Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 2-17-2-1 Tsukisamu-Higashi, Toyohira-ku, Sapporo, Hokkaido 062-8517, Japan)
Material： Journal of Bioscience and Bioengineering
Volume： 127  Issue： 4  Page： 451-457  Publication year： Apr. 2019 
JST Material Number： G0535B  ISSN： 1389-1723  CODEN： JBBIF6  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： Aspergillus oryzae ,...
Semi thesaurus term： *菌体外放出

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Author keywords (5)： Free dihomo-γ-linolenic acid ,  Aspergillus oryzae ,  Metabolic engineering ,  Surfactant ,  Extracellular release

JST classification (2)： Microbial metabolite production  (FK03020A) ,  Microorganism physiology in general  (EG03051L)

Substance index (2)： Arachidonic Acid ,  Dihomo-γ-linolenic acid

Reference (33)：

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• Choi, Y. M., Diehl, J., and Levins, P. C.: Promising alternative clinical uses of prostaglandin F2α analogs: beyond the eyelashes, J. Am. Acad. Dermatol., 72, 712-716 (2015).
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• Dyall, S. C.: Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA, Front. Aging Neurosci., 7, 52 (2015).

Terms in the title (4)： Aspergillus ,  ジホモ-γ-リノレン酸 ,  界面活性剤 ,  放出