Rchr
J-GLOBAL ID:200901019683290450
Update date: Sep. 04, 2024
Sasai Yasushi
ササイ ヤスシ | Sasai Yasushi
Affiliation and department:
Job title:
Professor
Research field (3):
Polymer materials
, Biomaterials
, Pharmaceuticals - analytical and physicochemistry
Research keywords (6):
polymer brushes
, controlled radical polymerization
, bioconjugates
, biocompatible surfaces
, plasma chemistry
, polymeric nano drug carriers
Research theme for competitive and other funds (16):
- 2021 - 2024 The use of nucleic acid aptamers as a removable masking agent for the controlled polymer modification of enzymes
- 2021 - 2024 Development of ammoniated DLC coating for artificial vascular graft and evaluation of influence of ammoniation and cardboxylation on DLC coating
- 2019 - 2022 Development of hybrid small diameter artificial vascular graft using DLC and MPC polymer
- 2018 - 2021 Synthesis of polymer-enzyme conjugates for site-specific modification of therapeutic proteins
- 2017 - 2020 Fabrication of polymer nano-film possessing hydrophobic and hydrophilic surface and its application to DDS
- 2015 - 2018 細胞培養技術への応用を指向した機能性ハイドロゲル薄膜の合成とその評価
- 2013 - 2015 高感度バイオセンシングを目指した金基板表面における抗体コンジュゲート界面の構築
- 2010 - 2014 Fundamental research on the development of high sensitive detection of target molecules by the use of self-assembled phospholipid layer possessing fluidity
- 2009 - 2012 培養細胞利用技術を支援する培養器材開発のための高分子表面の複合機能化
- 2007 - 2009 プラズマ照射高分子表面を利用した細胞固定化用機能性バイオインターフェイスの設計
- 2005 - 2007 Development of a novel immobilization method of biomolecules onto polymer surfaces by plasma techniques for the fabrication ofbiochips
- 2002 - 2004 Development of novel "patient-tailored DDS"by plasma technique
- Development of biomedical materials by plasma treatment
- Preparation of drug-containing composite powder using mechanochemical reaction
- Changes of physicochemical property on cellulose derivatives for pahrmaceutical additive by mechanical milling
- Fundamental Study of Plasma Chemistry and Its Application for Drug Engineering
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Papers (84):
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Yasuhiro Fujii, Tatsuyuki Nakatani, Daiki Ousaka, Susumu Oozawa, Yasushi Sasai, Shingo Kasahara. Development of Antimicrobial Surfaces Using Diamond-like Carbon or Diamond-like Carbon-Based Coatings. International journal of molecular sciences. 2024. 25. 16
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Naoki Doi, Yukinori Yamauchi, Yasushi Sasai, Kaho Suzuki, Masayuki Kuzuya, Shin-ichi Kondo. Dextran-based nanoparticles with 5-FU-conjugated polymethacrylate segments for drug delivery: Synthesis of amphiphilic graft copolymers by mechanochemical solid-state polymerization and characterization. International Journal of Biological Macromolecules. 2024. 132950-132950
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Sasai Yasushi, Ousaka Daiki, Fujii Yasuhiro, Isono Aoi, Yamauchi Yukinori, Kondo Shin-ichi, Nakatiani Tatsuyuki. Surface Functionalization of Diamond-like Carbon Film with Biocompatible Polymer Brushes. Journal of Photopolymer Science and Technology. 2022. 35. 4. 303-308
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Naoki Doi, Yukinori Yamauchi, Ryo Ikegami, Masayuki Kuzuya, Yasushi Sasai, Shin-ichi Kondo. Photo-responsive polymer micelles from o-nitrobenzyl ester-based amphiphilic block copolymers synthesized by mechanochemical solid-state copolymerization. Polymer Journal. 2020. 52. 12. 1375-1385
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Yukinori Yamauchi, Naoki Doi, Shin-ichi Kondo, Yasushi Sasai, Masayuki Kuzuya. Characterization of a novel polymeric prodrug of an antibacterial agent synthesized by mechanochemical solid-state polymerization. Drug Development Research. 2020. 81. 7. 867-874
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MISC (3):
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Yukinori Yamauchi, Shin-Ichi Kondo, Naoki Doi, Yasushi Sasai, Masayuki Kuzuya. The photopolymer science and technology award. Journal of Photopolymer Science and Technology. 2020. 33. 1. 7-9
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Yasushi Sasai. Synthesis and Evaluation of Functional Hydrogel Thin Films for Application to Cell Culture Technology. Impact. 2019. 2019. 3. 44-46
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笹井 泰志. プラズマ技術によるバイオセンサー構築のための生体分子固定化用高分子表面の設計(平成18年度岐阜薬科大学特別研究費(奨励)). 岐阜藥科大學紀要. 2007. 56. 35-36
Lectures and oral presentations (27):
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バイオセンサーの基本設計とDLCの活用の可能性
(日本医用DLC研究会第5回研究会 2023)
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Application of DNA aptamer to bovine trypsin as a high-affinity removable masking agent
(2023)
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Characterization of DNA Aptamer as a Removable Trypsin Inhibitor
(The 32nd Annual Meeting of MRS-J 2022)
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Surface functionalization of diamond-like carbon film with biocompatible polymer brushes
(The 39th International Conference of Photopolymer Science and Technology 2022)
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無機・有機ハイブリッド型医療材料開発にむけて
(第1回日本医用DLC研究会 2020)
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Education (4):
- 1998 - 2000 Gifu Pharmaceutical University Graduate School Department of Pharmaceutical Science
- - 2000 Gifu Pharmaceutical University Graduate School, Division of Pharmaceutical Sciences Pharmaceutical Physical Chemistry
- - 1998 Gifu Pharmaceutical University Faculty of Pharmaceutical Science Department of Manufacturing Pharmacy
- - 1998 Gifu Pharmaceutical University Faculty of Pharmaceutical Science Department of Manufacturing Pharmacy
Professional career (1):
- Doctor (Pharmacy) (Gifu Pharmaceutical University)
Work history (8):
- 2020/04 - 現在 Gifu University of Medical Science Faculty of Pharmacy Professor
- 2012/04 - 2020/03 Gifu Pharmaceutical University Laboratory of Pharmaceutical Physical Chemistry Associate Professor
- 2015/06 - 2016/05 Ecole Polytechnique Fédérale de Lausanne (EPFL) Visiting professor
- 2007/10 - 2012/03 Gifu Pharmaceutical University Laboratory of Pharmaceutical Physical Chemistry Associate Professor
- 2007/04 - 2007/09 Gifu Pharmaceutical University Laboratory of Pharmaceutical Physical Chemistry Assistant Professor
- 2001/04 - 2007/03 - 岐阜薬科大学 助手
- 2001 - - Research Associate, Gifu Pharmaceutical
- University
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Committee career (3):
- 2019/08 - 現在 Japanese Association for DLC Medical Application Trustee
- 2017/04 - 2020/03 日本薬学会 ファルマシアアドバイザー
- 2014/04 - 2017/03 日本薬学会 ファルマシア委員
Awards (1):
- 2009/07 - The International Plasma Chemistry Society Young Scientists Best Paper Award 2009
Association Membership(s) (3):
THE MATERIALS RESEARCH SOCIETY OF JAPAN
, The Society of Polymer Science, Japan
, The Pharmaceutical Society of Japan
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