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J-GLOBAL ID：202002216019340280   Reference number：20A2537432

Characterization of a novel polymeric prodrug of an antibacterial agent synthesized by mechanochemical solid-state polymerization

メカノ化学固相重合により合成した抗菌剤の新規高分子プロドラッグのキャラクタリゼーション【JST・京大機械翻訳】

Author (5)： Yamauchi Yukinori (Department of Pharmaceutical Physical Chemistry, College of Pharmaceutical Sciences, Matsuyama University, Matsuyama, Ehime, Japan) ,  Doi Naoki (Laboratory of Pharmaceutical Physical Chemistry, Department of Drug Delivery Technology and Sciences, Gifu Pharmaceutical University, Gifu, Japan) ,  Kondo Shin-ichi (Laboratory of Pharmaceutical Physical Chemistry, Department of Drug Delivery Technology and Sciences, Gifu Pharmaceutical University, Gifu, Japan) ,  Sasai Yasushi (Laboratory of Pharmaceutical Physical Chemistry, Department of Drug Delivery Technology and Sciences, Gifu Pharmaceutical University, Gifu, Japan) ,  Kuzuya Masayuki (Department of Health and Welfare, Faculty of Human Welfare, Chubu Gakuin University, Gifu, Japan)
Material： Drug Development Research  (Drug Dev Res)
Volume： 81  Issue： 7  Page： 867-874  Publication year： 2020 
JST Material Number： T0003A  ISSN： 0272-4391  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Abstract/Point： Polycrystalline methacryloyl m...

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Thesaurus term： Hydrolysis ,  thermal analysis ,  Colon ,  *antibacterial drug ,  monomer ,  *macromolecule ,  polycrystal ,  carboxy group ,  *mechanochemistry ,  *prodrug ,  in vitro experiment ,  pH ,  Anhydrides ,  powder X-ray diffraction ,  controlled drug release
Semi thesaurus term： 徐放 , 【Automatic Indexing@JST】

Author keywords (5)： acid anhydride bond ,  antibacterial agent ,  controlled release ,  mechanochemical polymerization ,  polymeric prodrug

JST classification (2)： Medical materials  (GA05040H) ,  Copolymerization  (CG04030D)

Terms in the title (6)： メカノ化学 ,  固相重合 ,  抗菌剤 ,  高分子 ,  プロドラッグ ,  キャラクタリゼーション