2014 - 2017 Drug discovery based on novel concept for overcoming high-risk myeloma which is still intractable despite of recent progress in the treatment
Tomofumi Yamamoto, Jun Nakayama, Yusuke Yamamoto, Masahiko Kuroda, Yutaka Hattori, Takahiro Ochiya. SORT1/LAMP2-mediated Extracellular Vesicle Secretion and Cell Adhesion Are Linked to Lenalidomide Resistance in Multiple Myeloma. Blood Advance. 2022
Yutaka Hattori, Takumi Futo, Ryo Uozaki, Daiju Ichikawa, Takashi Yamaguchi, Tomofumi Yamamoto, Maiko Matsushita, Maki Hirao. Integrin β5 and β7 expression in lenalidomide-resistant multiple myeloma cells. International Journal of Hematology. 2022. 115. 4. 605-608
Nagase K, Edatsune G, Nagata Y, Matsuda J, Ichikawa D, Yamada S, Hattori Y, Kanazawa H. Thermally-modulated cell separation columns using a thermoresponsive block copolymer brush as a packing material for the purification of mesenchymal stem cells. Biomaterials Science. 2021. 9. 21. 7054-7064
Matsushita M, Saito S, Yokoe S, Ichikawa D, Hattori Y. Characteristics of a novel target antigen against myeloma cells for immunotherapy. Vaccines. 2020. 8. 4. 1-13
Nagase K, Ishii S, Ikeda K, Yamada S, Ichikawa D, Akimoto A.M, Hattori Y, Kanazawa H. Antibody drug separation using thermoresponsive anionic polymer brush modified beads with optimised electrostatic and hydrophobic interactions. Scientific Reports. 2020. 10. 1
A novel candidate for immunological target in treatment of multiple myeloma.
(An AACR Special Conference on Tumor Immunology and Immunotherapy 2019)
Diverse molecular mechanisms of lenalidomide resistance in multiple myeloma cells
(81th Annual meeting of the Japanese Society of Hematology 2019)
Dedifferentiation by reprogramming genes augmented drug resistance and clonal growth in myeloma cells
(81th annual meeting of the Japanese Society of Hematology 2019)
Novel compound derived from natural products, komaroviquinone, showed anti-myeloma activity in vivo
(78th annual meeting of the Japanese cancer association 2019)
2005 - International Myeloma Foundation Horinouchi Research Grant受賞
2004/12/04 - 国際骨髄腫財団 IMF Grant Program Aki Horinouchi Research Grant Molecular targeting and gene-therapy of angiogenic growth factors for the treatment of refractory multiple myeloma.
2002 - がん研究振興財団がん研究助成受賞
2002 - がん研究振興財団がん研究助成受賞
2001 - Waxmann財団研究助成受賞
2001 - Waxmann財団研究助成
1992 - 国立がんセンター田宮記念賞受賞
1992 - 上原記念生命科学財団研究奨励賞受賞
1992 - 上原記念生命科学財団研究奨励賞
1992 - 国立がんセンター田宮記念賞
1991 - 財団法人 成人病医学研究振興財団 研究助成受賞
1991 - 財団法人 佐川がん研究助成金振興財団Promotional Funds受賞
1991 - 財団法人 佐川がん研究助成金振興財団Promotional Funds
1991 - 財団法人 成人病医学研究振興財団 研究助成
1990 - 公益信託 西記念癌研究者育成基金受賞
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Association Membership(s) (6):
The Japanese Society of Hematology
, The Japanese Society of Internal Medicine
, The Japanese Cancer Association
, American Society of Hematology
, The Japanese Society of Myeloma
, The Pharmaceutical Society of Japan