Art

J-GLOBAL ID：201902216338649310   Reference number：19A0885297

A Challenge to Aging Society by microRNA in Extracellular Vesicles: microRNA in Extracellular Vesicles as Promising Biomarkers and Novel Therapeutic Targets in Multiple Myeloma

細胞外小胞におけるマイクロRNAによる老化社会への挑戦: 多発性骨髄腫における有望なバイオマーカーおよび新規治療標的としての細胞外小胞におけるマイクロRNA【JST・京大機械翻訳】

Author (5)： Yamamoto Tomofumi (Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan) ,  Yamamoto Tomofumi (Clinical Physiology and Therapeutics, Keio University Faculty of Pharmacy, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-0011, Japan) ,  Kosaka Nobuyoshi (Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan) ,  Hattori Yutaka (Clinical Physiology and Therapeutics, Keio University Faculty of Pharmacy, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-0011, Japan) ,  Ochiya Takahiro (Division of Molecular and Cellular Medicine, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan)
Material： Journal of Clinical Medicine (Web)
Volume： 7  Issue： 3  Page： 55  Publication year： 2018 
JST Material Number： U7214A  ISSN： 2077-0383  Document type： Article
Article type： 文献レビュー  Country of issue： Switzerland (CHE)  Language： ENGLISH (EN)

Abstract/Point： Multiple myeloma (MM) is a mal...

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Thesaurus term： pathogenesis ,  differentiation (biology) ,  *senile change ,  *Multiple Myeloma ,  interaction ,  *biomarker ,  secretion (physiology) ,  gene ,  Prognosis ,  molecular mechanism ,  *MicroRNAs ,  *Extracellular Vesicles
Semi thesaurus term： 臨床応用 ,  悪性腫瘍 ,  *治療標的 , 【Automatic Indexing@JST】

Author keywords (5)： extracellular vesicles ,  exosome ,  microRNA ,  multiple myeloma ,  biomarker

JST classification (5)： Metabolic diseases,nutritional diseases in general.  (GD05010J) ,  Basic medicine on cardiovascular system  (GJ01020K) ,  Fishes  (FH02020K) ,  Basic medicine on respiratory system  (GI01020H) ,  Diagnosis of tumors(=neoplasms)  (GE03020J)

Reference (79)：

• Denzer, K.; Kleijmeer, M.J.; Heijnen, H.F.; Stoorvogel, W.; Geuze, H.J. Exosome: From internal vesicle of the multivesicular body to intercellular signaling device. J. Cell Sci. 2000, 19, 3365-3374.
• Raposo, G.; Stoorvogel, W. Extracellular vesicles: Exosomes, microvesicles, and friends. J. Cell Biol. 2013, 200, 373-383.
• Yanez-Mo, M.; Siljander, P.R.; Andreu, Z.; Zavec, A.B.; Borras, F.E.; Buzas, E.I.; Buzas, K.; Casal, E.; Cappello, F.; Carvalho, J.; et al. Biological properties of extracellular vesicles and their physiological functions. J. Extracell. Vesicles 2015, 4, 27066.
• Cocucci, E.; Meldolesi, J. Ectosomes and exosomes: Shedding the confusion between extracellular vesicles. Trends Cell Biol. 2015, 25, 364-372.
• Yoshioka, Y.; Konishi, Y.; Kosaka, N.; Katsuda, T.; Kato, T.; Ochiya, T. Comparative marker analysis of extracellular vesicles in different human cancer types. J. Extracell. Vesicles 2013, 2, 20424.

Terms in the title (7)： 細胞外小胞 ,  マイクロRNA ,  老化 ,  社会 ,  多発性骨髄腫 ,  バイオマーカー ,  治療標的