Rchr
J-GLOBAL ID：200901025126403802
Update date: Oct. 04, 2024
Takeuchi Kenji
タケウチ ケンジ | Takeuchi Kenji
Affiliation and department：
Job title：
Associate Professor
Homepage URL (1)：
http://www.setsunan.ac.jp/
Research field (2)：
Pharmaceuticals - health and biochemistry
, Molecular biology
Research theme for competitive and other funds (5)：
- Regulatory mechanism for the c-fos expression in HGF/SF and EGF signaling pathway
- HGF/SFとEGFの情報伝達系の比較によるc-Fos発現制御機構に関する検討
- 抗癌剤の作用機構の解明
- 抗癌剤耐性克服を利用した新しい癌治療法の確立
- 抗癌剤に対する耐性機構の解明
Papers (15)：
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Yamazawa R, Kuwana R, Takeuchi K, Takamatsu H, Nakajima Y, Ito K. Identification of the active site and characterization of a novel sporulation-specific cysteine protease YabG from Bacillus subtilis. The Journal of Biochemistry. 2022. 171. 3. 315-324
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K. Takeuchi, F. Ito and P. T. Thuong. Anti-Growth Activity of Tanshinone IIA towards Gefitinib-Sensitive and ?Resistant NonSmall Cell Lung Cancer Cells. International Journal of Plant Biology & Research. 2014. 2. 3. 1020-1024
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P. T. Thuong, N. M. Khoi, H. Kanta, K. Takeuchi. Ent-Kaurane Diterpenoids from Croton Tonkinensis Induce Apoptosis in Colorectal Cancer Cells through the Phosphorylation of JNK Mediated by Reactive Oxygen Species and Dual-Specificity JNK Kinase MKK4. Anti-cancer agents in medicinal chemistry. 2014. 14
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Maruyama S, Takeuchi K, Ito F, Kawasaki K. RecQ5 interacts with Rad51 and is involved in resistance of Drosophila to cisplatin treatment. Biological & Pharmaceutical Bulletin. 2012. 35. 11. 2017-2022
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K. Takeuchi, Viet, K. Kawasaki, K. Nishio, F. Ito. JNK-Mediated FOXO Expression Plays a Critical Role in EGFR Tyrosine Kinase Inhibitor-Induced BIM Expression and Apoptosis. Journal of Cancer Therapy. 2012. 3. 4A. 424-434
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Lectures and oral presentations (84)：
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EGFR-TKI耐性ヒト非小細胞肺がん細胞のMEK阻害剤併用処理によるアポトーシス誘導機構
(第96回日本生化学会大会)
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Bcl-2family分子阻害剤によるEGFR-TKI耐性ヒト非小細胞肺がんの抗がん剤耐性克服機構
(第73回 日本薬学会関西支部総会・大会)
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好熱菌Geobacillus sterothermophilus SpoIVAのポリマー化に関する研究
(第73回 日本薬学会関西支部総会・大会)
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結晶構造解析を目指した好熱菌Geobacillus sterothermophilus YabGの精製と結晶化
(第73回 日本薬学会関西支部総会・大会)
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YabGプロテアーゼのN末端領域は活性を阻害する
(第73回 日本薬学会関西支部総会・大会)
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Education (2)：
- - 1992 Setsunan University Graduate School, Division of Pharmaceutical Sciences
- - 1990 Setsunan University Faculty of Pharmaceutical Science
Professional career (2)：
Association Membership(s) (3)：
日本分子生物学会
, 日本生化学会
, 日本薬学会
