Rchr

J-GLOBAL ID：200901026667684827 Update date: Sep. 10, 2023

Nishimura Hiroyuki

ニシムラヒロユキ | Nishimura Hiroyuki

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.cc.toin.ac.jp/sc/bio/

Research field (3)： Immunology , Molecular biology , Genetics

Research keywords (6)：分子生物学 , 免疫遺伝学 , 免疫学 , molecular biology , immunogenetics , immunology

Research theme for competitive and other funds (8)：

2011 - 2013 SLE発症をもたらす枢軸的異常シグナル経路の解明
2004 - 2006 進行性腎障害に関する調査研究(研究分担者)
2003 - 2005 全身性自己免疫疾患モデルマウスにおける免疫寛容破綻を規定する遺伝子の探索
2000 - 2002 SLEモデルにおけるCD4陽性T細胞の自発的活性化を規定する遺伝子の探索
Linkage Studies on Multigenic Diseases

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Papers (85)：

Lin Q, Ohtsuji M, Amano H, Tsurui H, Tada N, Sato R, Fukuyama H, Nishimura H, Verbeek JS, Hirose S. FcγRIIb on B Cells and Myeloid Cells Modulates B Cell Activation and Autoantibody Responses via Different but Synergistic Pathways in Lupus-Prone Yaa Mice. Journal of immunology (Baltimore, Md. : 1950). 2018. 201. 11. 3199-3210
Mareki Ohtsuji, Qingshun Lin, Hideki Okazaki, Kazuko Takahashi, Hirofumi Amano, Hideo Yagita, Hiroyuki Nishimura, Sachiko Hirose. Anti-CD11b antibody treatment suppresses the osteoclast generation, inflammatory cell infiltration, and autoantibody production in arthritis-prone FcγRIIB-deficient mice. Arthritis Research and Therapy. 2018. 20. 1. 25
Haga T, Toei J, Mitsui K, Ohtsuji M, Kodera Y, Osada M, Nishimura H. Aberrant light-induced depression is associated with impaired sensorimotor gating in mice. World J. Neurosci. 2018. 8. 1. 1-9
Mareki Ohtsuji, Qingshun Lin, Keiko Nishikawa, Naomi Ohtsuji, Hideki Okazaki, Hiromichi Tsurui, Hirofumi Amano, Toshikazu Shirai, Norihiro Nishimoto, Hiroyuki Nishimura, et al. IL-6 signal blockade ameliorates the enhanced osteoclastogenesis and the associated joint destruction in a novel Fc gamma RIIB-deficient rheumatoid arthritis mouse model. MODERN RHEUMATOLOGY. 2015. 25. 2. 270-277
Masumi Ohta, Hiroyuki Nishimura, Yoshinobu Asada. Association of DLX3 gene polymorphism and dental caries susceptibility in Japanese children. ARCHIVES OF ORAL BIOLOGY. 2015. 60. 1. 55-61

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MISC (45)：

Cig regulatory region polymorphism down-regulating murine Cig protein levels with linkage to lupus nephritis. J.Immunol. 2002. 169,1334-1339
Genome screening for susceptibility loci in systemic lupus ercthematosus. Am.J.Pharmacogenomics. 2002. 2,1-12
H Okamoto, K Asamitsu, H Nishimura, N Kamatani, T Okamoto. Reciprocal modulation of transcriptional activities between HIV-1 tat and MHC class II transactivator CIITA. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2000. 279. 2. 494-499
Seven-color fluoresce imaging of tissue samples based on Fourier spectroscopy and singular value decomposition. J.Histochem Cytochem. 2000. 48,653-662
Practical approaches to determining disease-susceptible loci in multigenic autoimmune models. Int. Rev.Immunol. 2000. 19. 335

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Books (1)：

Immunology and immunopathology of the autoimmune disease of N2B and related mouse strains (Rihova, V and Vetvicka, V eds)
CRC Press, Boca Raton Fla 1991

Works (2)：

DNA反応ロボットの稼動ソフトウェアの開発
2000 -
Studies on Automated Genotyping
2000 -

Education (5)：

1981 - 1984 Tokyo Institute of Technology Graduate School of Science
- 1984 Tokyo Institute of Technology Science of Engineering
- 1984 Tokyo Institute of Technology Graduate School, Division of Science and Engineering
- 1979 Tokyo Institute of Technology School of Science Dept. of Chemistry
- 1979 Tokyo Institute of Technology Faculty of Science

Professional career (1)：

Ph D (Tokyo Institute of Technology)

Work history (13)：

2005/04 - 現在 Toin University of Yokohama Faculty of Biomedical Engineering Professor
2005/04 - 現在 Toin University of Yokohama Faculty of Biomedical Engineering
1997/04 - 2005/03 Toin University of Yokohama Faculty of Engineering Professor
1994/04 - 1997/03 桐蔭学園横浜大学工学部教授
1994/04 - 1996/03 - Toin University Faculty of Engineering Professor

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Association Membership(s) (5)：

日本リウマチ学会 , 日本生化学会 , 日本癌学会 , 日本分子生物学会 , 日本免疫学会

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