Rchr
J-GLOBAL ID:200901028531580559
Update date: Oct. 31, 2024
Nakajima Yoshihiro
ナカジマ ヨシヒロ | Nakajima Yoshihiro
Affiliation and department:
Job title:
研究グループ長
Homepage URL (1):
http://www.aist.go.jp/RESEARCHERDB/cgi-bin/worker_detail.cgi?call=namae&rw_id=Y39424034
Research field (2):
Molecular biology
, Cell biology
Research theme for competitive and other funds (15):
- 2022 - 2025 化学物質のシグナルかく乱作用を基にした新規in vitro催奇形性評価原理の解明
- 2021 - 2024 多色リアルタイム発光測定法によるストレス応答経路間のクロストークの解明
- 2016 - 2019 Analysis of mice modified with genes controlling the amplitude of circadian rhythm by CRISPR / Cas9 method
- 2016 - 2019 Development of visualizing system of microRNA dynamism
- 2016 - 2018 The effect of payload conjugates on VHH antibody
- 2015 - 2018 Hierarchical self-organization of circadian system: synchronization of cellular oscillators and pacemaker coupling
- 2014 - 2017 Biosynthesis-inspired deracemizative production of firefly D-luciferin
- 2012 - 2015 Development of highly accurate and sensitive quantification method for protein and peptide in biological matrix
- 2011 - 2012 Improvement of efficiency of piPS cell development
- 2009 - 2011 Analysis of intracellular localization of clock protein by means of bioluminescence imaging technique
- 2007 - 2008 Analyses of molecular mechanisms underlying circadian rhythm generation and synchronization by rapid and efficient gene transduction in vivo
- 2006 - 2007 異種細胞の遺伝子発現同時検出可能な共培養系による生体時計同調機構解析
- 2004 - 2005 細胞内pHの日周変動を測定するプローブの開発
- 2004 - 2005 灌流培養型連続発光モニター系を用いた概日リズムの同調機構解析
- 2002 - 2003 発光性甲殻類分布海域を指標とした地球温暖化評価に関する研究
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Papers (96):
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Tatsunosuke Tomita, Yoshihiro Nakajima, Yoshihiro Ohmiya, Koyomi Miyazaki. Novel three-dimensional live skin-like in vitro composite for bioluminescence reporter gene assay. The FEBS journal. 2024
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Yosuke Tabei, Yoshihiro Nakajima. IL-1β-activated PI3K/AKT and MEK/ERK pathways coordinately promote induction of partial epithelial-mesenchymal transition. Cell communication and signaling : CCS. 2024. 22. 1. 392-392
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Kazuo Nakazawa, Minako Matsuo, Yo Kikuchi, Yoshihiro Nakajima, Rika Numano. Melanopsin DNA aptamers can regulate input signals of mammalian circadian rhythms by altering the phase of the molecular clock. Frontiers in neuroscience. 2024. 18. 1186677-1186677
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Yosuke Tabei, Hiroko Abe, Shingo Suzuki, Nobuaki Takeda, Jun-Ichiro Arai, Yoshihiro Nakajima. Sedanolide Activates KEAP1-NRF2 Pathway and Ameliorates Hydrogen Peroxide-Induced Apoptotic Cell Death. International journal of molecular sciences. 2023. 24. 22
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Haruna Takeda, Yoshihiro Nakajima, Teruaki Yamaguchi, Itaru Watanabe, Shoko Miyoshi, Kodai Nagashio, Hiroki Sekine, Hozumi Motohashi, Hajime Yano, Junya Tanaka. The anti-inflammatory and anti-oxidative effect of a classical hypnotic bromovalerylurea mediated by the activation of NRF2. Journal of biochemistry. 2023. 174. 2. 131-142
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MISC (5):
Patents (12):
Books (15):
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菌体外多糖を産生する阿波晩茶由来乳酸菌の加熱死菌体によるマウスマクロファージ様RAW264.7細胞の活性化-Activation of Macrophage-like Raw264.7 Cells by Heat-treated Lactic Acid Bacteria that Produce Exopolysaccharide Isolated from Awa-bancha
徳島 : 徳島県立工業技術センター 2023
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【染色体医工学】人工染色体ベクターを用いた発光安定細胞の樹立と利用
(株)ニュー・サイエンス社 2020
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発光イメージング実験ガイド : 動物細胞におけるシングルセル発光イメージング
羊土社 2019 ISBN:9784758122405
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高知県産バイオマスの利活用に関する研究-Study on utilization of biomass from Kochi prefecture
高知 : 高知県工業技術センター 2019
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Cell dynamics research using multi-color beetle luciferases
2015
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Lectures and oral presentations (119):
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ヒトiPS細胞を用いた長時間のシグナルかく乱検出による発生毒性評価
(人工臓器 2023)
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シグナル伝達相互作用による発生制御機構とその破綻による発生毒性の予測 多色リアルタイム発光測定システムの構築とセルベースアッセイへの応用
(The Journal of Toxicological Sciences 2023)
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ヒトiPS細胞を用いた長時間のシグナル攪乱検出による発生毒性評価
(The Journal of Toxicological Sciences 2023)
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Detection and Discrimination of Yeasts by Using Micropore Devices
(応用物理学会秋季学術講演会講演予稿集(CD-ROM) 2022)
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Real-time luminescence monitoring of signal disruption to evaluate the developmental toxicity for pharmaceuticals
(日本分子生物学会年会プログラム・要旨集(Web) 2022)
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