Mori Kazunori

モリカズノリ | Mori Kazunori

Affiliation and department：
Job title： Associate professor
Homepage URL (1)： https://rira.showa-u.ac.jp/profile/ja.7761d5640499c779095d9bef5d1233b3.html

Research keywords (3)： Reactive oxygen species , Mitochondria , 足場依存性増殖

Research theme for competitive and other funds (14)：

2022 - 2025 転移抑制を目指したRac1によるintegrin β4の分解抑制機構の解明
2021 - 2025 Respiratory chain activity as a target of tumor-agnostic therapy in highly glycolytic/low respiratory tumors
2019 - 2022 Impact of mitochondrial complex I activity on cancer cell proliferation: importance of NAD+ levels
2018 - 2021 転写制御因子SUZ12によるレドックス制御を介した足場非依存性増殖機構の解析
2015 - 2018 A mitochondrial ROS pathway controls matrix metalloproteinase 9 levels and invasive properties in RAS-activated cancer cells

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Papers (26)：

Hidetsugu Nakagawa, Masato Higurashi, Fumihiro Ishikawa, Kazunori Mori, Motoko Shibanuma. An indispensable role of TAZ in anoikis resistance promoted by OTUB1 deubiquitinating enzyme in basal-like triple-negative breast cancer cells. Biochemical and biophysical research communications. 2023. 649. 1-9
Tsuyoshi Maruyama, Koji Saito, Masato Higurashi, Fumihiro Ishikawa, Yohko Kohno, Kazunori Mori, Motoko Shibanuma. HMGA2 drives the IGFBP1/AKT pathway to counteract the increase in P27KIP1 protein levels in mtDNA/RNA-less cancer cells. Cancer Science. 2022. 114. 1. 152-163
Kazunori Mori, Masato Higurashi, Fumihiro Ishikawa, Motoko Shibanuma. Rac1-mediated sustained β4 integrin level develops reattachment ability of breast cancer cells after anchorage loss. Cancer science. 2021. 112. 8. 3205-3217
Akira Ota, Masataka Tajima, Kazunori Mori, Erika Sugiyama, Vilasinee Hirunpanich Sato, Hitoshi Sato. The selective cytotoxicity of silver thiosulfate, a silver complex, on MCF-7 breast cancer cells through ROS-induced cell death. Pharmacological reports : PR. 2021. 73. 3. 847-857
Mirei Mizuno, Kazunori Mori, Keisuke Tsuchiya, Takashi Takaki, Takashi Misawa, Yosuke Demizu, Motoko Shibanuma, Kiyoshi Fukuhara. Design, Synthesis, and Biological Activity of Conformationally Restricted Analogues of Silibinin. ACS omega. 2020. 5. 36. 23164-23174

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MISC (94)：

森一憲, 中川英嗣, 日暮大渡, 石川文博, 柴沼質子. A role of TAZ in anoikis resistance promoted by OTUB1 deubiquitinating enzyme in triple-negative breast cancer cells. 日本癌学会学術総会抄録集(Web). 2023. 82nd
日暮大渡, 森一憲, 中川英嗣, 石川文博, 柴沼質子. A role of NAD⁺-SIRT3/6 axes in control of p21^Cip1 expression and cancer cell proliferation. 日本癌学会学術総会抄録集(Web). 2023. 82nd
中川英嗣, 森一憲, 日暮大渡, 石川文博, 柴沼質子. Stabilization of the oncogene TAZ by the deubiquitinating enzyme OTUB1 contributes to anchorage-independent cell survival in breast cancer cells. 日本薬学会年会要旨集(Web). 2023. 143rd
中川英嗣, 石川文博, 森一憲, 柴沼質子. 乳癌細胞の足場非依存性生存におけるTAZの役割(Role of TAZ in promoting cell survival upon anchorage loss in breast cancer cells). 日本癌学会総会記事. 2022. 81回. P-1151
丸山剛, 斉藤光次, 斉藤光次, 日暮大渡, 石川文博, 河野葉子, 森一憲, 柴沼質子. HMGA2 drives IGFBP1/AKT pathway to counteract the increase in P27KIP1 protein in mitochondria-deficient cancer cells. 日本癌学会学術総会抄録集(Web). 2022. 81st

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Lectures and oral presentations (44)：

A role of NAD+-SIRT3/6 axes in control of p21Cip1 expression and cancer cell proliferation
(2023)
A role of TAZ in anoikis resistance promoted by OTUB1 deubiquitinating enzyme in triple-negative breast cancer cells
(2023)
Polycomb-group protein SUZ12 suppresses anoikis by alleviating oxidative stress in cancer cells
(2023)
脱ユビキチン化酵素OTUB1によるがん遺伝子TAZの安定化とその足場非依存性生存能への寄与
(日本薬学会第143年会 2023)
Role of TAZ in promoting cell survival upon anchorage loss in breast cancer cells
(2022)

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Professional career (1)：

Committee career (3)：

Awards (2)：

2020 - FEBS Press The FEBS Journal Richard Perham Prizewinner 2020 A mitochondrial ROS pathway controls matrix metalloproteinase 9 levels and invasive properties in RAS-activated cancer cells
2007/05 - 日本組織培養学会日本組織培養学会奨励賞足場非依存性細胞増殖へのcyclin D1の関与

Association Membership(s) (2)：

THE JAPANESE TISSUE CULTURE ASSOCIATION , THE JAPANESE CANCER ASSOCIATION

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