Rchr

J-GLOBAL ID：200901030627633160 Update date: Aug. 27, 2024

IKEDA Masa-Aki

イケダマサアキ | IKEDA Masa-Aki

Affiliation and department：
Homepage URL (2)： http://www.tmd.ac.jp/grad/emb/emb-J.htm , http://ikeda-emb-tmd.hp.infoseek.co.jp/

Research field (3)： Regenerative dentistry and dental engineering , Oral medicine (pathology) , Oral medicine

Research keywords (3)： Bone regeneration , Tissue engineering , 分子生物学

Research theme for competitive and other funds (14)：

2015 - 2017 直接分化転換によるヒト成人皮膚・口腔粘膜細胞からの再生歯誘導の試み
2014 - 2016 ヒト線維芽細胞から骨・軟骨細胞への直接分化転換と硬組織再生への応用
2012 - 2014 インスレーターの解除による細胞のリプログラミングと骨細胞への直接分化転換の試み
2012 - Regenaration of hard tissue using Mesenchymal stem cells
1997 - 2012 癌抑制に関与するクロマチン転写制御機構と口腔癌における制御異常

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Papers (27)：

Sedin Nasuh, Sibel Oguzkan Balci, Ibrahim Bozgeyik, Masa-Aki Ikeda, Muhammetnur Tekayev, Khandakar A S M Saadat. ARID3A and ARID3B exert direct regulatory control over the long non-coding RNAs (lncRNAs) MALAT1 and NORAD within the context of non-small cell lung cancer (NSCLC). Pathology, research and practice. 2023. 252. 154948-154948
Shintaro Yamazaki, Yujing Lin, Eriko Marukawa, Masa-Aki Ikeda. Integrated Bone Formation Through In Vivo Endochondral Ossification Using Mesenchymal Stem Cells. Journal of visualized experiments : JoVE. 2023. 197
Shintaro Yamazaki, Ryoko Hirayama, Yayoi Ikeda, Sachiko Iseki, Tetsuya Yoda, Masa-Aki Ikeda. Hyaluronic acid hydrogels support to generate integrated bone formation through endochondral ossification in vivo using mesenchymal stem cells. PloS one. 2023. 18. 2. e0281345
Cuneyd Parlayan, Yunus Sahin, Zekiye Altan, Kaifee Arman, Masa-Aki Ikeda, Khandakar A S M Saadat. ARID3A regulates autophagy related gene BECN1 expression and inhibits proliferation of osteosarcoma cells. Biochemical and biophysical research communications. 2021. 585. 89-95
Saadat KASM, Lestari W, Pratama E, Ma T, Iseki S, Tatsumi M, Ikeda MA. Distinct and overlapping roles of ARID3A and ARID3B in regulating E2F-dependent transcription via direct binding to E2F target genes. International journal of oncology. 2021. 58. 4

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MISC (99)：

K. Arman, Y. Z. Igci, K. A. S. M. Saadat, Z. Altan, Y. Sahin, M. A. Ikeda, M. Igci. Opposite roles of lncRNA ERICD (E2F1-regulated inhibitor of cell death) and ARID3A (AT-rich interaction domain 3A) in osteosarcoma, glioblastoma and lung cancer. FEBS JOURNAL. 2016. 283. 282-283
Yayoi Ikeda, Masahito Takiguchi, Yuko Matsunaga, Masa-Aki Ikeda. Expression of the cell cycle regulator cyclin E in the subgranular layer of the mouse hippocampal dentate gyrus. NEUROSCIENCE RESEARCH. 2010. 68. E365-E365
Iwanaga R, Ozono E, Fujisawa J, Ikeda MA, Okamura N, Huang Y, Ohtani K. Activation of the cyclin D2 and cdk6 genes through NF-kB is critical for cell cycle progression induced by HTLV-I Tax. Oncogene (in press). 2009
Eiko Ozono, Hideyuki Komori, Ritsuko Iwanaga, Masa-Aki Ikeda, Sachiko Iseki, Kiyoshi Ohtani. E2F-like elements in p27(Kip1) promoter specifically sense deregulated E2F activity. GENES TO CELLS. 2009. 14. 1. 89-99
Eiko Ozono, Hideyuki Komori, Ritsuko Iwanaga, Masa-Aki Ikeda, Sachiko Iseki, Kiyoshi Ohtani. E2F-like elements in p27(Kip1) promoter specifically sense deregulated E2F activity. Genes to cells : devoted to molecular & cellular mechanisms. 2009. 14. 1. 89-99

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Patents (2)：

終末分化細胞の増殖方法及びそのための組換えベクター
Methods for proliferating terminal differentiated cells and recombinant vectors therefor

Books (17)：

Therapeutic Targeting of p53-Mediated Apoptosis Pathway in Head and Neck Squamous Cell Carcinomas:
2012
Distinct transcriptional regulation by E2F in cell growth and tumor suppression. "Control of cellular physiology by the transcription factor E2F" p91-105
Research Signpost 2008
キーワードで理解する転写イラストマップ
羊土社 2005
発生における細胞増殖制御(共著)
シュプリンガー・フェアラーク東京 2004
心筋の増殖停止機構「発生における細胞増殖制御」 p101-109
シュプリンガー・フェアラーク東京 2004

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Lectures and oral presentations (24)：

Investigation of culture conditions and scaffolds for human mesenchymal stem cells suitable for bone regeneration via endochondral ossification
(The 42nd Annual Meeting of the Japanese Society of Inflammation and Regeneration 2021)
ARID3B modulates E2F target gene expression and cell proliferation.
(2019年度生命科学系学会合同年次大会 2019)
Gene-Silencing Efficiency Determination of ARID3B in Osteosarcoma Cell Lines by siRNA and shRNA
(6th International Multidisciplinary Studies Congress 2019)
Gene-Silencing Efficiency Determination of ARID3B in Osteosarcoma Cell Lines by siRNA and shRNA
(III. International Eurasia Multidisciplinary Studies Congress 2019)
ARID3A Regulates the Tumor Suppressor Tap73 in Osteosarcoma
(2nd ZEUGMA International Congress on Multidisciplinary Studies 2019)

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Works (6)：

卵巣発生におけるエストロゲンの作用機序に関する研究
2000 - 2003
Joint Research on Action of Estrogen in the Developing Ovary
1999 - 2003
心筋および神経細胞の増殖と細胞死の分子機序に関する研究
1996 - 2003
Joint Research on Molecular Mechanism of Cell Growth and Apoptosis in Cardiomyocytes and Neurons
1996 - 2003
転写仲介因子p300のがん抑制機序に関する研究
1997 - 2002

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Education (4)：

- 1987 Tokyo Medical and Dental University
- 1987 Tokyo Medical and Dental University Graduate School, Division of Dental Research
- 1983 Tokyo Medical and Dental University Faculty of Dentistry School of Dentistry
- 1983 Tokyo Medical and Dental University Faculty of Dentistry

Professional career (1)：

Doctor (Dentistry) (Tokyo Medical and Dental University)

Work history (33)：

2023/04 - 現在 Tokyo Medical and Dental University Department of Regenerative and Reconstructive Dental Medicine Graduate School of Medical and Dental Sciences Lecturer
2022/04 - 2023/03 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Maxillofacial and Neck Reconstruction Molecular Craniofacial Embryology Lecturer
2018/04 - 2022/03 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Maxillofacial and Neck Reconstruction Molecular Craniofacial Embryology Lecturer
1987/09/01 - 2018/03/31 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Maxillofacial and Neck Reconstruction Molecular Craniofacial Embryology Associate Professor
1996 - 2003 Tokyo Medical and Dental University

1996 - 2003 Associate professor, Graduate school,

1992 - 1996 Tokyo Medical and Dental University

1992 - 1996 Lecturer, Faculty of Dentistry,

1991 - 1994 デューク大学ハワードヒューズ医学研究所研究員

1991 - 1994 Research Associate,

1987 - 1992 Tokyo Medical and Dental University

1987 - 1992 Research Associate, Faculty of Dentistry,

Associate Professor, Section of Molecular Embryology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan

2000-present

Associate Professor, Department of Developmental Biology, Graduate School of Dentistry, Tokyo Medical and Dental University, Tokyo, Japan

1996-2000

Lecturer, Department of Developmental Biology, Graduate School of Dentistry, Tokyo Medical and Dental University, Tokyo, Japan

1992-1996

Research associate, Department of Genetics, Howard Hughes Medical Institute, Duke University Medical Center, North Carolina, USA

1991-1994

Research Associate, Department of Oral Microbiology, Faculty of Dentistry, Tokyo Medical and Dental University, Tokyo, Japan

1988-1992

Research Associate, Section of Craniofacial Development and Anomalies, Institute of Stomatognathic Science, Faculty of Dentistry, Tokyo Medical and Dental University, Tokyo, Japan

1987-1988

同大学院医歯学総合研究科分子発生学分野助教授 1999年4月〜2007年3月、同准教授 2007年4月未設定

デューク大学医学部ハワードヒューズ医学研究所研究員 1991年8月〜1994年8月、未設定

同大学院生体機能制御歯科学系発生機構制御学講座講師 1992年4月〜1996年11月、未設定

同歯学部口腔細菌学教室助手 1988年9月〜1992年3月、未設定

東京医科歯科大学歯学部顎口腔研究施設顎顔面発生機構研究部門助手1987年9月〜1988年8月、未設定

Tokyo Medical and Dental University

Duke University Medical Center

Howard Hughes Medical Institute,

Tokyo Medical and Dental University

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Awards (1)：

2003 - 第35回(財)病態代謝研究会研究助成金

Association Membership(s) (15)：

American Heart Association , 日本循環器学会 , 日本口腔科学会 , 歯科基礎医学会 , 日本癌学会 , 日本分子生物学会 , 口腔病学会 , American Heart Association , The Japanese Circulation Society , The Japanese Stomatological Society , The Stomatological Society, Japan , Japanese Association for Oral Biology , The Japanese Biochemical Society , The Japanese Cancer Association , The Molecular Biology Society of Japan

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