Research keywords (1):
Biotechnology and Bioengineering,Applied Biochemistry,Molecular Engineering
Research theme for competitive and other funds (13):
2021 - 2024 人工知能を活用した抗真菌剤の開発研究
2021 - 2024 Development of new synthetic methods for bioactive compounds based on chirality control in living organisms
2018 - 2021 The biocatalytic CO2-fixation catalyzed by (de)carboxylases and application to the production of various aromatic carboxylic acids
2016 - 2019 Screening and characterization of microorganisms for the production of hydroxytyrosol
2016 - 2018 Development of novel reactions for amide bond formation and creation of peptide-like functional materials
2014 - 2017 Development of amide compounds production using functional biomolecules
2010 - 2013 Funactional Analysis of a novel poly-amino acid synthesizing enzyme for synthesis of a desired oligopeptide.
2006 - 2008 Development and Application of Screening Methods for Amino Acid Hydroxylase
2002 - 2006 環境に優しい酵素に関する研究
2001 - 2003 Biodesulfurization using thermophilic bacteria and identification of bds genes
1999 - 2003 微生物機能を利用した資源循環型水環境プロセスの構築
2000 - 2002 Screening of a novel glucosyl condensing enzyme showing the activity of glycoside synthesis and the application of this enzyme to useful glycoside production
2000 - 2000 ダイナミックな分子デザインと変異集積による制限酵素の改変
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Papers (333):
Jun Ohnuki, Yasuhiro Arimura, Tomonori Kono, Kuniki Kino, Hitoshi Kurumizaka, Mitsunori Takano. Electrostatic Ratchet for Successive Peptide Synthesis in Nonribosomal Molecular Machine RimK. Journal of the American Chemical Society. 2023. 145. 29. 15963-15970
Shota Karakama, Shin Suzuki, Kuniki Kino. One-pot synthesis of 2,5-diketopiperazine with high titer and versatility using adenylation enzyme. Applied Microbiology and Biotechnology. 2022. 106. 12. 4469-4479
Megumi Matsude, Himeka Okamoto, Riku Aono, Kuniki Kino. Tryptophanase gene deficiency improves the application of dioxygenase to 3-(2-hydroxyethyl)catechol production. Journal of Bioscience and Bioengineering. 2021. 132. 3. 241-246
Ryotaro Hara, Yuta Nakajima, Hiroaki Yanagawa, Ryo Gawasawa, Izumi Hirasawa, Kuniki Kino. Enzymatic Synthesis of l-threo-β-Hydroxy-α-Amino Acids via Asymmetric Hydroxylation Using 2-Oxoglutarate-Dependent Hydroxylase from Sulfobacillus thermotolerans Y0017. Applied and environmental microbiology. 2021. AEM0133521
Kazuki Kawanabe, Riku Aono, Kuniki Kino. 2,5-Furandicarboxylic acid production from furfural by sequential biocatalytic reactions. Journal of Bioscience and Bioengineering. 2021. 132. 1. 18-24
Ryotaro Hara, Kengo Hirai, Shin Suzuki, Kuniki Kino. A chemoenzymatic process for amide bond formation by an adenylating enzyme-mediated mechanism. Scientific Reports. 2018. 8. 1