Okumura Nobuaki

オクムラノブアキ | Okumura Nobuaki

Affiliation and department：
Job title： Associate Professor

Research field (2)： Zoological sciences , Functional biochemistry

Research keywords (4)： Proteomics , Physiology , Protein science , Biochemistry

Research theme for competitive and other funds (16)：

2015 - 2018 Substrate specificity and physiological function of mammalian dipeptidases
2011 - 2013 Function and metabolism of a histidine-containing dipeptide, carnosine, in mammals
2010 - 2012 Mass Spectrometry of Metalloproteins and High-Molecular-Weight Protein Complexes
2008 - 2010 Analyses of molecular mechanisms of homeostasis by carnosine in mammals and carnosine-hydrolyzing enzyme, CNDP2
2004 - 2006 Molecular Mechanism of Photic Entrainment of Mammalian Circadian Clock

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Papers (67)：

Shuichi Mitsunaga, Nobuaki Okumura, Toshiki Takei, Toshifumi Takao, Hironobu Tsubouchi, Kohei Nakata, Masafumi Nakamura, Yuji Kitahata, Hideki Motobayashi, Masafumi Ikeda, et al. Identification of a urinary CD276 fragment for detecting resectable pancreatic cancer using a C-terminal proteomics strategy. Scientific Reports. 2024. 14. 1
Takuma Kozono, Chifuyu Jogano, Wataru Okumura, Hiroyuki Sato, Hitomi Matsui, Tsubasa Takagi, Nobuaki Okumura, Toshifumi Takao, Takashi Tonozuka, Atsushi Nishikawa. Cleavage of the Jaw1 C-terminal region enhances its augmentative effect on the Ca2+ release via IP3 receptors. Journal of Cell Science. 2023. 136. 4. jcs260439
Toshiki Takei, Hideaki Tanaka, Nobuaki Okumura, Toshifumi Takao, Luis Moroder, Hironobu Hojo. Chemical synthesis of per-selenocysteine human epidermal growth factor. Journal of peptide science : an official publication of the European Peptide Society. 2022. e3464
Ayana Isobe, Yasuha Arai, Daisuke Kuroda, Nobuaki Okumura, Takao Ono, Shota Ushiba, Shin-ichi Nakakita, Tomo Daidoji, Yasuo Suzuki, Takaaki Nakaya, et al. ACE2 N-glycosylation modulates interactions with SARS-CoV-2 spike protein in a site-specific manner. Communications Biology. 2022. 5. 1. 1188-1188
Sho Kobayashi, Takujiro Homma, Nobuaki Okumura, Jia Han, Keita Nagaoka, Hideyo Sato, Hiroyuki Konno, Sohsuke Yamada, Toshifumi Takao, Junichi Fujii. Carnosine dipeptidase II (CNDP2) protects cells under cysteine insufficiency by hydrolyzing glutathione-related peptides. Free radical biology & medicine. 2021. 174. 12-27

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MISC (14)：

坪内拡伸, 柳重久, 松元信弘, 三浦綾子, 奥村宣明, 高尾敏文, 中里雅光. 尿中微量蛋白断片解析による新規肺腺癌診断マーカーの探索. 日本臨床分子医学会学術総会プログラム・抄録集. 2018. 55回. 50-50
Katsuya Nagai, Mamoru Tanida, Akira Niijima, Nobuo Tsuruoka, Yoshinobu Kiso, Yuko Horii, Jiao Shen, Nobuaki Okumura. Role of L-carnosine in the control of blood glucose, blood pressure, thermogenesis, and lipolysis by autonomic nerves in rats: involvement of the circadian clock and histamine. Amino acids. 2012. 43. 1. 97-109
Nobuaki Okumura, Kozo Sudo, Toshifumi Takao. [Urinary peptidomics]. Nihon Jinzo Gakkai shi. 2010. 52. 4. 485-8
Hachiro Nakagawa, Nobuaki Okumura. Coordinated regulation of circadian rhythms and homeostasis by the suprachiasmatic nucleus. Proceedings of the Japan Academy. Series B, Physical and biological sciences. 2010. 86. 4. 391-409
永井克也, 谷田守, 福島洋一, 山野俊彦, 新島旭, 前田景子, 奥村宣明, 堀井裕子, 沈嬌. 乳酸菌の腸内投与による自律神経活動と生理機能の変化. 腸内細菌学雑誌. 2009. 23. 3. 209-216

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Books (9)：

How the heart beats?
2018 ISBN:9784759819816
Imidazole dipeptides : chemistry, analysis, function and effects
Royal Society of Chemistry 2015 ISBN:1849738904
Handbook of proteolytic enzymes, 3rd ed.
Elsevier Academic Press 2013 ISBN:9780123822192
タンパク質実験ノート〈下〉タンパク質をしらべよう
羊土社 2011 ISBN:9784897069449
タンパク質実験ノート〈上〉タンパク質をとり出そう
羊土社 2011 ISBN:4897069432

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Education (4)：

- 1988 Osaka University
- 1988 Osaka University Graduate School, Division of Natural Science
- 1986 Osaka University School of Science
- 1986 Osaka University Faculty of Science

Association Membership(s) (3)：

日本プロテオーム学会 , 日本分子生物学会 , 日本生化学会

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