Rchr
J-GLOBAL ID：200901036866152058   Update date: Nov. 05, 2024

Okamoto Hiroaki

オカモト ヒロアキ | Okamoto Hiroaki
Affiliation and department：
Jichi Medical University School of Medicine, Department of Infection and Immunity, Division of Virology

About Jichi Medical University School of Medicine, Department of Infection and Immunity, Division of Virology


Job title： Professor
Homepage URL  (1)： http://www.jichi.ac.jp/virology/
Research field  (2)： Virology ,  Molecular biology
Research keywords  (22)： Fulminant hepatitis ,  Replication mechanism ,  Molecular epidemiology ,  Cell culture ,  Monoclonal antibody ,  Genetic mutation ,  Anellovirus ,  GB virus ,  Torque teno virus ,  Zoonosis ,  Hepatitis E virus ,  Hepatitis delta virus ,  Hepatitis C virus ,  Hepatitis B virus ,  Hepatitis A virus ,  Molecular cloning ,  分子ウイルス学 ,  ウイルス肝炎 ,  肝炎ウイルス ,  Molecular virology ,  Viral Hepatitis ,  Hepatitis viruses
Research theme for competitive and other funds  (16)：
  • 2023 - 2026 Study of Prevention, Pathological Development and Treatment for Hepatitis A and E Virus Infection
  • 2013 - 2015 Research on mechanism of hepatitis E virus egress utilizing membrane traffic
  • 2011 - 2012 Studies on the identification and acquisition mechanism ofcell-derived membrane on the surface of hepatitis E virus particles
  • 2010 - 2012 Research on release mechanism, genome mutations and cellular receptor of hepatitis E virus (HEV) using cell culture systems for HEV
  • 2007 - 2008 Characterization of hepatitis E virus (HEV) particles and analysis of replication mechanism by using a cell culture system for HEV
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Papers (733)：
  • Tokio Sasaki, Keisuke Kakisaka, Akio Miyasaka, Masao Nishiya, Naoki Yanagawa, Hidekatsu Kuroda, Takayuki Matsumoto, Masaharu Takahashi, Hiroaki Okamoto. Correction: Spontaneous reactivation of hepatitis B virus with multiple novel mutations in an elderly patient with resolved hepatitis B virus infection. Clinical journal of gastroenterology. 2024. 17. 5. 1001-1002
  • Masaharu Takahashi, Tsutomu Nishizawa, Akira Nishizono, Manri Kawakami, Yukihiro Sato, Kazunori Kawakami, Masahiko Irokawa, Tomoko Tamaru, Shinichi Miyazaki, Mizuho Shimada, et al. Recent decline in hepatitis E virus prevalence among wild boars in Japan: Probably due to countermeasures implemented in response to outbreaks of classical swine fever virus infection. Virus research. 2024. 348. 199438-199438
  • Tokio Sasaki, Keisuke Kakisaka, Akio Miyasaka, Masao Nishiya, Naoki Yanagawa, Hidekatsu Kuroda, Takayuki Matsumoto, Masaharu Takahashi, Hiroaki Okamoto. Spontaneous reactivation of hepatitis B virus with multiple novel mutations in an elderly patient with resolved hepatitis B virus infection. Clinical journal of gastroenterology. 2024
  • Tatsuo Kanda, Shuhei Arima, Reina Sasaki-Tanaka, Mai Totsuka, Masayuki Honda, Ryota Masuzaki, Naoki Matsumoto, Masahiro Ogawa, Masaharu Takahashi, Hiroaki Okamoto, et al. Severe hepatitis E virus genotype 3b in a patient with alcohol-associated liver disease: A case report. Medicine International. 2024. 4. 3
  • Rei Hirano, Tatsuo Kanda, Masayuki Honda, Shuhei Arima, Mai Totsuka, Ryota Masuzaki, Shini Kanezawa, Reina Sasaki-Tanaka, Naoki Matsumoto, Hiroaki Yamagami, et al. Hepatitis E Virus Infection Caused Elevation of Alanine Aminotransferase Levels in a Patient with Chronic Hepatitis B and Choledocholithiasis. Reports. 2023. 6. 4. 55-55
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MISC (679)：
  • 長嶋茂雄, プリマダルシニ プトゥプラティウィ, 西山尚志, 高橋雅春, 村田一素, 岡本宏明. 発光タグHiBiTを保有する組換えE型肝炎ウイルスの開発と薬剤スクリーニングへの応用. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2022. 69th
  • Yuichi Yamazaki, Takashi Ueno, Takeshi Hatanaka, Satoshi Takakusagi, Daichi Takizawa, Atsushi Naganuma, Takashi Kosone, Hiroaki Nakajima, Ken Sato, Satoru Kakizaki, et al. Characteristics of cases of hepatitis E in Gunma prefecture: Small epidemics caused by the same subgenotype 3a strains. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY. 2021. 36. 87-88
  • Putu Prathiwi Primadharsini, Shigeo Nagashima, Hiroaki Okamoto. Mechanism of Cross-Species Transmission, Adaptive Evolution and Pathogenesis of Hepatitis E Virus. VIRUSES-BASEL. 2021. 13. 5
  • 大城幸雄, 岡本宏明, 鈴木修司. わが国の臓器移植患者におけるE型肝炎ウイルス感染追跡調査. 肝臓. 2020. 61. Supplement 2
  • 大城 幸雄, 大和田 洋平, 稲垣 勇紀, 大河内 信弘, 岡本 宏明. 【A型・E型肝炎up-to-date】E型肝炎慢性化とその対策. 消化器・肝臓内科. 2019. 6. 1. 83-88
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Patents (25)：
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Books (5)：
  • Virus Taxonomy: Ninth Report of the International Committee on Taxonomy of Viruses
    Elsevier 2011
  • TT Viruses-The Still Elusive Human Pathogens. (jointly worked)
    Springer 2009 ISBN:9783540709718
  • Virus Taxonomy: Classification and Nomenclature of Viruses.Eighth Report of the International Committee on the Taxonomy of Viruses.(jointly worked)
    Elsevier/Academic Press 2005 ISBN:0122499514
  • Viral Hepatitis: Molecular Biology, Diagnosis, Epidemiology and Control.(jointly worked)
    Elsevier 2004 ISBN:0444514872
  • The use of a preS2-containing recombinant vaccine for the prevention of maternal transmission of hepatitis B virus in Indonesian neonates.(jointly worked)
    Viral Hepatitis and Liver Diseases 1994
Education (1)：
  • 1973 - 1979 Tohoku University Faculty of Medicine School of Medicine
Professional career (1)：
  • (BLANK) (Jichi Medical University)
Work history (6)：
  • 2020/04 - 現在 Jichi Medical University
  • 2020/04 - 現在 Jichi Medical University
  • 2003/04 - 2020/03 Jichi Medical University Professor
  • 1998 - 2003 Jichi Medical University
  • 1987 - 1998 Jichi Medical University
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Awards (4)：
  • 2008 - 第44回小島三郎記念文化賞
  • 2000 - ISI Citation Laureate Award
  • 1997 - 第1回日本肝臓学会賞(織田賞)
  • 1992 - 第2回日経BP技術賞大賞
Association Membership(s) (6)：
日本臨床ウイルス学会 ,  日本ウイルス学会 ,  日本内科学会 ,  日本消化器病学会 ,  日本肝臓学会 ,  American Society for Microbiology
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