Rchr
J-GLOBAL ID：200901046764938117
Update date: Feb. 01, 2024
Takeshima Tsuguhide
タケシマ ツグヒデ | Takeshima Tsuguhide
Affiliation and department：
Research field (4)：
Tumor diagnostics and therapeutics
, Cell biology
, Immunology
, Radiology
Research keywords (7)：
樹状細胞
, 好中球
, CTL
, 放射線治療
, 腫瘍免疫
, 免疫治療
, 放射線生物学
Research theme for competitive and other funds (7)：
- 2022 - 2025 同所移植モデルによる難治性腫瘍免疫応答を誘導する免疫療法と放射線の併用戦略の検討
- 2019 - 2022 Improvement of conventional adoptive cell therapy for cancer utilized tumor-specific immune responses induced by radiation therapy
- 2019 - 2022 Quantitative evaluation of radiation-induced immunostimulating effect
- 2018 - 2019 放射線がん治療後に誘導される抗腫瘍免疫応答を利用した新規がん治療法の開発
- 2012 - 2015 がん細胞は自身の生存をかけ放射線域を逃れるべく上皮間葉移行をなしうるか
- 2011 - 2011 癌特異的キラーT細胞を軸にした新規放射線・免疫併用癌治療モデルの開発
- 2009 - 2010 Development of a new radiation therapy to improve tumor immunity using tumor-bearing mouse with in vivo imaging technique
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Papers (26)：
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Liqiu Ma, Yoshimitsu Sakamoto, Ken Ando, Hidetoshi Fujita, Akihisa Takahashi, Tsuguhide Takeshima, Hiromi Otsuka, Daniel K Ebner, Kazuhiro Kakimi, Takashi Imai, et al. Th Balance-Related Host Genetic Background Affects the Therapeutic Effects of Combining Carbon-Ion Radiation Therapy With Dendritic Cell Immunotherapy. International journal of radiation oncology, biology, physics. 2022. 112. 3. 780-789
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Rumiana Bakalova, Severina Semkova, Donika Ivanova, Zhivko Zhelev, Thomas Miller, Tsuguhide Takeshima, Sayaka Shibata, Dessislava Lazarova, Ichio Aoki, Tatsuya Higashi. Selective Targeting of Cancerous Mitochondria and Suppression of Tumor Growth Using Redox-Active Treatment Adjuvant. Oxidative Medicine and Cellular Longevity. 2020. 2020. 1-30
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Dan Ishihara, Laurentiu Pop, Tsuguhide Takeshima, Puneeth Iyengar, Raquibul Hannan. Rationale and evidence to combine radiation therapy and immunotherapy for cancer treatment. CANCER IMMUNOLOGY IMMUNOTHERAPY. 2017. 66. 3. 281-298
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Tsuguhide Takeshima, Laurentiu M. Pop, Aaron Laine, Puneeth Iyengar, Ellen S. Vitetta, Raquibul Hannan. Key role for neutrophils in radiation-induced antitumor immune responses: Potentiation with G-CSF. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2016. 113. 40. 11300-11305
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武島 嗣英. 放射線・免疫治療学の発展. 放射線生物研究. 2015. 50. 4. 353-369
ｍore...
Patents (2)：
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免疫賦活作用及び/又はアレルギー抑制作用を有し、且つ胃液耐性を有する新規乳酸菌
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糸状菌を用いる乳酸菌の培養方法及び該培養方法により得られる培養物
Education (3)：
- - 2003 Hokkaido University
- - 2000 Hokkaido University
- - 1998 Hokkaido University School of Fisheries Sciences
Professional career (1)：
Work history (9)：
- 2018 - 現在 National Institutes for Quantum and Radiological Science and Technology
- 2017 - 2018 National Institutes for Quantum and Radiological Science and Technology
- 2013 - 2017 米国テキサス大学サウスウエスタン医学センター Instructor
- 2011 - 2013 米国テキサス大学サウスウエスタン医学センター Assistant Instructor
- 2008 - 2011 Hokkaido University Graduate School of Medicine
- 2006 - 2008 Hokkaido University Graduate School of Medicine
- 2004 - 2006 日生バイオ株式会社 研究員
- 2003 - 2004 Hokkaido University Institute for Genetic Medicine
- 2003 - Hokkaido University Institute for Genetic Medicine
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