Tai Akihiro

タイアキヒロ | Tai Akihiro

Affiliation and department：
Job title： Professor

Research field (4)： Bioorganic chemistry , Pharmacology , Pharmaceuticals - health and biochemistry , Molecular biochemistry

Research keywords (2)： Food chemistry , Bioorganic chemistry

Research theme for competitive and other funds (6)：

2022 - 2025 Research to create homoisoflavonoid analogues with both AChE inhibitory and neurite outgrowth promoting activities.
2017 - 2020 Screening of ascorbate-binding proteins in plant using novel stable ascorbate probes
2016 - 2019 Syntheses and structure-activity relationship studies of diaryl ether type PTP 1B inhibitors
2005 - 2007 真菌類由来アスコルビン酸類似体の動物における機能解明並びに生物学的利用
1999 - 2000 Studies on the factors that can regulate neuro-immune-cross talks

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Papers (102)：

Takeru Koga, Naoaki Kawahara, Mei Aburada, Asako Ono, Shiori Mae, Aina Yoshida, Yuji Iwaoka, Hideyuki Ito, Akihiro Tai. Antiallergic activity of 3-O-dodecyl-L-ascorbic acid. Molecules. 2024. 29. 1. 69
Takeru Koga, Hideyuki Ito, Yuji Iwaoka, Toshiro Noshita, Akihiro Tai. Neurite outgrowth-promoting compounds from the petals of Paeonia lactiflora in PC12 cells. Molecules. 2022. 27. 22. 7670
Takeru Koga, Nanako Shiki, Hideyuki Ito, Yuji Iwaoka, Akihiro Tai. Degranulation inhibitors from petals of Coreopsis grandiflora. Records of Natural Products. 2022. 16. 6. 645-650
Yuji Iwaoka, Misaki Fukushima, Hideyuki Ito, Takeru Koga, Naoaki Kawahara, Akihiro Tai. Synthesis of ascorbic acid derivatives with different types of C8 straight acyl chain and their neurite outgrowth-enhancing activities. Journal of Nutritional Science and Vitaminology. 2022. 68. 3. 236-239
Takeru Koga, Akihiro Tai. Neurite outgrowth-promoting compounds from cockscomb hydrolysate. Nutrients. 2022. 14. 7. 1422

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MISC (24)：

田井章博. アスコルビン酸(ビタミンC)誘導体. バイオインダストリー. 2023. 40. 8. 32-39
田井章博. アスコルビン酸誘導体を用いた医薬品開発への可能性. ビタミン. 2022. 96. 7. 311-321
岩岡裕二, 福嶋美咲, 伊東秀之, 田井章博. 2-O-α-D-Glucopyranosyl-6-O-(2-propylpentanoyl)-L-ascorbic acidの高効率的かつ低コストな合成プロセス. ビタミン. 2022. 96. 5•6. 230-233
三浦香織, 松野弘明, 岩岡裕二, 伊東秀之, 田井章博. 6-Deoxy-2-O-methyl-6-(N-hexadecanoyl)amino-L-ascorbic acidの抗アレルギー作用. ビタミン. 2021. 95. 11. 483-486
田井章博. アスコルビン酸誘導体を用いた基礎研究から応用研究まで. ビタミン. 2019. 93. 9. 383-393

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Patents (14)：

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Books (3)：

Lectures and oral presentations (96)：

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Education (3)：

Professional career (2)：

Work history (5)：

2019 - 現在 Tokushima University Graduate School of Technology, Industrial and Social Science Professor
2012 - 2019 Prefectural University of Hiroshima Faculty of Life and Environmental Sciences Professor
2008 - 2012 Prefectural University of Hiroshima Faculty of Life and Environmental Sciences Associate Professor
2005 - 2008 Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Associate Professor
1996 - 2005 Okayama University Faculty of Pharmaceutical Sciences Assistant Professor

Awards (3)：

2010/11 - 日本薬学会メディシナルケミストリーシンポジウム優秀賞 1型・2型糖尿病モデルで経口血糖降下作用を示すベンゾトリアゾール型レチノイドX受容体パーシャルアゴニスト
2007/05 - 日本ビタミン学会奨励賞親油性安定型アスコルビン酸誘導体の創製とその特性に関する研究
2006/09 - 日本農芸化学会中四国支部奨励賞アスコルビン酸誘導体及び食品成分の生体機能調節作用に関する研究

Association Membership(s) (3)：

The Vitamin Society of Japan , The Pharmaceutical Society of Japan , Japan Society for Bioscience, Biotechnology, and Agrochemistry

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