Kakegawa Tomohito

カケガワトモヒト | Kakegawa Tomohito

Affiliation and department：

Research field (1)： Pharmaceuticals - health and biochemistry

Research keywords (5)： translatome , 創傷治癒 , 翻訳調節 , Wound Healing , Translational Control

Research theme for competitive and other funds (21)：

2017 - 2018 サンブスギによる地域再生の可能性に関する化学的・遺伝的研究
2014 - 2017 Role of the myosin light chain kinase (MLCK) participating in cellular multiplication
2013 - 2014 制度改正後の一般用医薬品販売における薬剤師の接客環境と業務実態
2006 - 2007 制度改正前の一般用医薬品販売における薬剤師の接客環境と業務実態
2005 - 2006 X-ray Crystallographic Study of Antibiotics resistant Proteins

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Papers (38)：

佐々木英久, 鈴木明子, 宮澤純子, 井上映子, 森健二, 懸川友人, 杉林堅次. 新型コロナワクチンの城西国際大学職域接種におけるワクチン接種動機と副反応の調査. 日本予防医学雑誌. 2022. 16. 2. 21-26
Tomohito Kakegawa, Lucia Satiko Yoshida, Mariko Takada, Mari Noguchi, Ken Yasukawa, Hiromi Takano-Ohmuro. Comparison of the effects of pachymic acid, moronic acid and hydrocortisone on the polysome loading of RNAs in lipopolysaccharide-treated THP-1 macrophages. Journal of Natural Medicines. 2019. 73. 1. 190-201
Lucia Satiko Yoshida, Tomohito Kakegawa, Yasukatsu Yuda, Hiromi Takano-Ohmuro. Shikonin changes the lipopolysaccharide-induced expression of inflammation-related genes in macrophages. JOURNAL OF NATURAL MEDICINES. 2017. 71. 4. 723-734
Tomohito Kakegawa, Aya Miyazaki, Ken Yasukawa. Anti-inflammatory effects of alpinone 3-acetate from Alpinia japonica seeds. JOURNAL OF NATURAL MEDICINES. 2016. 70. 3. 653-660
Kimiko Kazumura, Lucia Satiko Yoshida, Akiko Nara, Hiroshi Tsuchiya, Naokazu Morishita, Hirokazu Kawagishi, Tomohito Kakegawa, Yasukatsu Yuda, Hiromi Takano-Ohmuro. Inhibition of neutrophil superoxide generation by shikonin is associated with suppression of cellular Ca2+ fluxes. JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION. 2016. 59. 1. 1-9

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MISC (12)：

Nozomi Ohuchi, Hiromi Takano-Ohmuro, Lucia Satiko Yoshida, Tomohito Kakegawa. Effects of shikonin in recovery of artificial wound: a differential gene expression study. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2010. 112. 167P-167P
T Fukamachi, H Saito, T Kakegawa, H Kobayashi. Different proteins are phosphorylated under acidic environments in Jurkat cells. IMMUNOLOGY LETTERS. 2002. 82. 1-2. 155-158
T Kakegawa, M Ito, A Hayakawa, M Matsuda, S Tamura, H Saito, RL Kaspar, H Kobayashi. Rapamycin induces binding activity to the terminal oligopyrimidine tract of ribosomal protein mRNA in rats. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 2002. 402. 1. 77-83
JF Zhu, A Hayakawa, T Kakegawa, RL Kaspar. Binding of the La autoantigen to the 5 ' untranslated region of a chimeric human translation elongation factor 1A reporter mRNA inhibits translation in vitro. BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION. 2001. 1521. 1-3. 19-29
Y Honma, Y Ishii, T Kasukabe, J Okabe-Kado, Y Yamamoto-Yamaguchi, T Kakegawa, A Awaya. Induction of differentiation of human myeloid leukemia cells by novel synthetic neurotrophic pyrimidine derivatives. EXPERIMENTAL HEMATOLOGY. 2001. 29. 2. 194-201

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Patents (2)：

MEDICINAL COMPOSITIONS
MEDICINAL COMPOSITIONS

Lectures and oral presentations (7)：

Analysis of genes whose expression is regulated in HaCaT cells by laser light in the wavelength range used for low-power laser therapy
(2024)
Consideration of the biological effects of Gynura procumbens leaf constituents in mouse 3t3l1-induced adipocytes
(The 143rd Annual Meeting of the Pharmaceutical Society of Japan (Sapporo) 2023)
Consideration of the biological effects of ultralow irradiation of 655 nm laser light on gene expression in HaCaT cells
(The 143rd Annual Meeting of the Pharmaceutical Society of Japan 2023)
茯苓由来トリテルペンpachymic acid の抗炎症作用機構の比較検討
(第37回生薬に関する懇談会(北里大学)、日本薬学会関東支部・(公社)東京生薬協会(東京) 2022)
Effect of clarithromycin on mRNA exon selection
(The 3rd Annual Meeting of the Japanese Society of Neutral Lipids 2019)

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Education (4)：

- 1982 Chiba University
- 1982 Chiba University Graduate School, Division of Pharmaceutical Sciences
- 1980 Chiba University Faculty of Pharmaceutical Sciences
- 1980 Chiba University Faculty of Pharmaceutical Science

Professional career (2)：

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Committee career (2)：

1999 - Japanese Biochemical Society Consol Kanto-branch
1992 - 1997 Pharmaceutical Society of Japan Area Reporter

Association Membership(s) (5)：

一般社団法人中性脂肪学会 , Japanese Cosmetic Science Society , Japanese Society for Wound Healing , Japanese Biochemical Society , The Pharmaceutical Society of Japan

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