Sugiyama Shigeru

スギヤマシゲル | Sugiyama Shigeru

Affiliation and department：
Job title：教授
Other affiliations (3)：

Osaka University Graduate School of Science Department of Chemistry Associate Professor
Osaka University Graduate School of Science, Department of Chemistry, Graduate School of Science Department of Chemistry
Osaka University Graduate School of Science, Department of Chemistry, Graduate School of Science Department of Chemistry

Research field (4)： Structural biochemistry , Crystal engineering , Molecular biochemistry , Biochemistry

Research keywords (4)：構造生物学 , タンパク質科学 , タンパク質工学 , タンパク質結晶学

Research theme for competitive and other funds (11)：

2023 - 2026 Average orientation of lipid acyl chains in the domain structure of model membranes
2020 - 2024 繊維芽細胞増殖因子FGF5と受容体の相互作用およびアプタマーの阻害機序の解明
2019 - 2022 Structure and recognition mechanism for nuclear receptors involved in bone formation
2016 - 2019 Structural basis for the regulation mechanism of intracellular polyamine concentration
2013 - 2016 Innovative technological development for the production of the complex crystal with high-strength hydrogel

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Papers (112)：

Shigeru Sugiyama, Daisuke Matsuoka, Toshiaki Hara, Masashi Sonoyama, Shigeru Matsuoka, Michio Murata. Experimental and theoretical investigations into the mechanism of interactions between membrane-bound fatty acids and their binding protein: A model system to investigate the behavior of lipid acyl chains in contact with proteins. Chemistry and Physics of Lipids. 2022. 105227-105227
Shigeru Sugiyama, Keisuke Kakinouchi, Hiroaki Adachi, Tsugio Nagasawa, Noriaki Kunimune, Michio Murata, Yusuke Mori. Growth of protein crystals in high-strength hydrogels with the dialysis membrane. Jpn. J. Appl. Phys. 2021. 60. 1. 015506-015506
Shigeru Sugiyama, Tomoya Kitatani, Taichi Naruse, Yumeto Otsuka, Hiroaki Adachi, Toshihiro Fujita, Yusuke Mori. Effect of ultra-fine bubble water on protein crystal nucleation. Jpn. J. Appl. Phys. 2020. 59. 11. 115505-115505
Hiroki Kondo, Masaki Kitagawa, Yuya Matsumoto, Masaya Saito, Marie Amano, Shigeru Sugiyama, Takashi Tamura, Hitoshi Kusakabe, Kenji Inagaki, Katsumi Imada. Structural basis of strict substrate recognition of L-lysine α-oxidase from Trichoderma viride. Protein Sci. 2020. 29. 11. 2213-2225
杉山成, 垣之内啓介, 廣田佳久, 中川公恵, 岡野登志夫, 村田道雄. 凝固ゲル中結晶化法を用いた骨形成に関与するステロイドX受容体の分子認識. 日本生化学会大会プログラム・講演要旨集. 2020. 93回. [P-144]

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MISC (26)：

喜多俊介, 秋田穂, 日下裕規, TIAN Cong, 田所高志, 井貫晋輔, 新山真由美, 杉山成, 村田道雄, 藤本ゆかり, et al. X-ray crystal structure analysis of MHC class I like molecule CD1d in complex with glycolipids. 日本蛋白質科学会年会プログラム・要旨集. 2022. 22nd (Web)
秋田穂, 日下裕規, TIAN Cong, 田所高志, 井貫晋輔, 新山真由美, 杉山成, 村田道雄, 藤本ゆかり, 喜多俊介, et al. Thermal stability analysis of lipid antigen presenting molecule, CD1d. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
秋田穂, 日下裕規, 田聡, 田所高志, 井貫晋輔, 新山真由美, 杉山成, 村田道雄, 藤本ゆかり, 喜多俊介, et al. MHC classI様分子CD1dとアミド型α-GarCer複合体のX線結晶構造解析. 日本結晶学会年会講演要旨集. 2021. 2021
喜多俊介, 日下裕規, HOSSAIN Md. Imran, 花島慎弥, 井貫晋輔, 田所高志, 新山真由美, 杉山成, 相羽俊彦, 相羽俊彦, et al. Crystal structure analysis of lipid presenting molecule CD1d. 量子ビームサイエンスフェスタ(Web). 2019. 2018
田川恭志郎, 杉山成, 天野亮, 神津知子, 坂本泰一. AML1タンパク質とアプタマーの複合体のX線結晶構造解析. 日本分子生物学会年会プログラム・要旨集(Web). 2019. 42nd

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Patents (4)：

Books (10)：

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Professional career (1)：

Association Membership(s) (5)：

日本ポリアミン学会 , 日本蛋白質科学会 , 日本化学会 , 日本生物物理学会 , 日本結晶学会

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