Rchr
J-GLOBAL ID：200901053159642032   Update date: Oct. 25, 2024

Akiba Hisaya

アキバ ヒサヤ | Akiba Hisaya
Affiliation and department：
Juntendo University Department of Immunology, Graduate School of Medicine

About Juntendo University Department of Immunology, Graduate School of Medicine


Job title： Associate Professor
Other affiliations (2)：
Homepage URL  (1)： https://goodhealth.juntendo.ac.jp/medical/000164.html
Research field  (5)： Immunology ,  Laboratory animal science ,  Allergies and connective tissue disease ,  Ophthalmology ,  Infectious disease
Research keywords  (7)： 免疫学 ,  アレルギー ,  自己免疫疾患 ,  モノクローナル抗体 ,  T細胞 ,  補助シグナル分子 ,  Costimulatory molecules
Research theme for competitive and other funds  (15)：
  • 2020 - 2024 自己免疫疾患・アレルギー疾患の病態を制御するTIM分子の機能解明
  • 2016 - 2019 The development of new antibody treatment against immune checkpoint protein PD-1 homolog
  • 2016 - 2019 Detection of human TIM-4 on autoimmune and allergic diseases
  • 2014 - 2017 Immune regulation for tissue transplantation and regeneration in the eye
  • 2014 - 2016 Immune regulation on autoimmune and allergic diseases by the TIM family molecules
Show all
Papers (130)：
  • Yuji Nozaki, Hisaya Akiba, Hiroki Akazawa, Hirotaka Yamazawa, Kaori Ishimura, Koji Kinoshita, Itaru Matsumura. Inhibition of the TIM-1 and -3 Signaling Pathway Ameliorates Disease in a Murine Model of Rheumatoid Arthritis. Clinical and experimental immunology. 2024
  • Tomonori Ochiai, Hajime Yasuda, Hisaya Akiba, Karin Ashizawa, Erina Hosoya, Jun Ando, Sachiko Miyake, Miki Ando. Ectopic band 3 expression as a cause of mature ovarian teratoma-associated secondary autoimmune hemolytic anemia. International journal of laboratory hematology. 2024
  • Yuuki Sandhu, Norihiro Harada, Sonoko Harada, Takayasu Nishimaki, Hitoshi Sasano, Yuki Tanabe, Tomohito Takeshige, Kei Matsuno, Ayako Ishimori, Yoko Katsura, et al. MAP3K19 Affects TWEAK-Induced Response in Cultured Bronchial Epithelial Cells and Regulates Allergic Airway Inflammation in an Asthma Murine Model. Current issues in molecular biology. 2023. 45. 11. 8907-8924
  • Yuichi Tsuchiya, Sachiko Komazawa-Sakon, Masato Tanaka, Takumi Kanokogi, Kenta Moriwaki, Hisaya Akiba, Hideo Yagita, Ko Okumura, Kevin C. Entzminger, C.J. Okumura, et al. A high-sensitivity ELISA for detection of human FGF18 in culture supernatants from tumor cell lines. Biochemical and Biophysical Research Communications. 2023. 675. 71-77
  • Hitoshi Sasano, Norihiro Harada, Sonoko Harada, Tomohito Takeshige, Yuuki Sandhu, Yuki Tanabe, Ayako Ishimori, Kei Matsuno, Tetsutaro Nagaoka, Jun Ito, et al. Pretreatment circulating MAIT cells, neutrophils, and periostin predicted the real-world response after 1-year mepolizumab treatment in asthmatics. Allergology international : official journal of the Japanese Society of Allergology. 2023
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MISC (172)：
  • Akiba Hisaya, Abe Yoshiyuki, Tabe Toko, Tamura Naoto, Miyake Sachiko. 関節リウマチ患者血清中の可溶性TIM-4の臨床的有用性に関する解析(Analysis of clinical utility of soluble TIM-4 in rheumatoid arthritis patient serum). 日本免疫学会総会・学術集会記録. 2023. 52. Proceedings. 501-501
  • Sandhu Yuuki, Harada Norihiro, Harada Sonoko, Sasano Hitoshi, Abe Sumiko, Ueda Shoko, Nishimaki Takayasu, Sato Yoshihiko, Watanabe Takayasu, Takeshige Tomohito, et al. 喘息のアレルギー性気道炎症におけるMAP3K19の役割(Role of MAP3K19 in Allergic Airway Inflammation of Asthma). 日本呼吸器学会誌. 2023. 12. 増刊. 373-373
  • Sasano Hitoshi, Harada Norihiro, Harada Sonoko, Takeshige Tomohito, Sandhu Yuuki, Tanabe Yuki, Ishimori Ayako, Matsuno Kei, Nagaoka Tetsutaro, Ito Jun, et al. 喘息患者におけるメポリズマブのバイオマーカーとしての血中MAIT細胞、好中球、ペリオスチン(Circulating MAIT cells, neutrophils, and periostin as biomarkers for mepolizumab in asthmatics). 日本呼吸器学会誌. 2023. 12. 増刊. 374-374
  • 田辺 悠記, 秋葉 久弥, 原田 紀宏, 原田 園子, 伊藤 潤, 蒲池 史卓, 三宅 幸子, 高橋 和久. 呼吸器病学の若手研究最前線 TIM-4はCD300bとの結合によりマスト細胞の活性化とアレルギー性肺炎を制御する. 日本呼吸器学会誌. 2023. 12. 増刊. 47-47
  • Tanabe Yuki, Akiba Hisaya, Harada Norihiro, Harada Sonoko, Takahashi Kazuhisa, Miyake Sachiko. アレルギー性疾患の分子的および細胞多様性(II) 血清中の可溶性TIM-4濃度は重症喘息の表現型と関連する(Molecular and cellular diversity of allergic diseases(II) Soluble TIM-4 levels in serum are associated with severe asthma phenotype). 日本免疫学会総会・学術集会記録. 2022. 51. Proceedings. WS21-P
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Patents (5)：
Books (1)：
  • カラー図解 臨床に役立つ免疫学
    メディカル・サイエンス・インターナショナル 2006
Lectures and oral presentations  (122)：
  • 免疫チェックポイントTIMの慢性炎症における働き
    (第36回呼吸器・免疫シンポジウム 2018)
  • ヒト気道上皮細胞におけるキチンによるPGE2産生誘導
    (第67回日本アレルギー学会学術集会 2018)
  • 気管支喘息のバイオマーカーとしての血清テネイシンC値の可能性
    (第67回日本アレルギー学会学術集会 2018)
  • Expression of TIM-4 in normal cornea and corneal grafts
    (The Annual Meeting of the Association for Research in Vision and Ophthalmology 2018)
  • Chitin Induced Airway Inflammation and Production of Prostaglandin E2
    (2018)
ｍore...
Works (1)：
  • 免疫系と神経、内分泌系の立体的分子機構の解明
    1996 - 2000
Education (4)：
  • - 2000 Juntendo University
  • 1988 - 1990 Kitasato University
  • 1984 - 1988 Kitasato University
  • - 1984 北海道立札幌東高等学校
Professional career (1)：
  • (BLANK) (Juntendo University)
Work history (10)：
  • 2018/04 - 現在 Japan Women's University Faculty of Science Department of Chemical and Biological Sciences
  • 2007/04 - 現在 Juntendo University Department of Immunology, Faculty of Medicine Associate Professor
  • 2007/04 - 現在 Juntendo University Faculty of Medicine
  • 2005/04 - 2007/03 Juntendo University Faculty of Medicine
  • 2005/04 - 2007/03 Juntendo University Faculty of Medicine
Show all
Committee career (1)：
  • 2016/10 - 現在 日本免疫学会 評議員
Association Membership(s) (3)：
JAPANESE SOCIETY OF ALLERGOLOGY ,  日本免疫学会 ,  臨床免疫学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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