Research field (4):
Food sciences
, Pathobiochemistry
, Cell biology
, Functional biochemistry
Research keywords (6):
分子医学
, 栄養代謝学
, 神経系の腫よう
, 基礎腫よう学
, tumor of nervous system
, basic oncology
Research theme for competitive and other funds (16):
2017 - 2020 Elucidation of molecular mechanisms regulating anabolic pathways after amino acid starvation
2015 - 2019 The fate of aneuploid cells
2012 - 2017 Primary cilia and cell cycle
2014 - 2016 Development of peptide inhibitors targeting ADAM10 to eradicate brain tumor-initiating cells
2012 - 2014 Elucidation of biological functions of CD133, a marker for brain tumor-initiating cells, and its application
2011 - 2014 Elucidation of new functions of intermediate filaments linking a relationship between proliferation and differentiation
2009 - 2011 Analysis of abnormal cell polarity in brain tumor cells
2010 - 2010 上皮間葉転換可視化システムを用いた癌浸潤転移阻害化合物スクリーニング
2008 - 2010 Antinomy of cell-cell adhesion and cell proliferation
2006 - 2007 Elucidation of the link between the control of cell-cell adhesion by regulations of cell polarity and cell proliferation and differentitation
2004 - 2005 Dissection of roles of Densin-180, a cell polarity molecule, in synapses
2004 - 2004 LAP蛋白質ERBINによる細胞極性制御機構の解明
2002 - 2003 Analysis of the regulation of intermediate filaments and desmosomes.
2001 - 2002 Analysis of Intermediate Filament Binding Proteins
2000 - 2001 Analysis of the regulation of simple epithelia-specific intermediate filament proteins, Keratin 8/18
Akihito Inoko, Miwako Nishizawa, Ichiro Izawa, Koh-Ichi Nagata, Jiro Usukura, Masaki Inagaki. Identification and characterization of a novel keratin binding protein, trichoplein(trichohyalin and plectin binding protein), as a desmosomal protein. CELL STRUCTURE AND FUNCTION. 2004. 29. 38-38
E Heikkila, H Ahola, E Astrom, Izawa, I, M Inagaki, H Holthofer. The nephrin-based fMolecular complex of the slit diaphragm: Direct interaction with the postsynaptic protein densin. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. 2003. 14. 319A-319A
K Nagata, A Kawajiri, T Shiromizu, N Saitoh, Izawa, I, TJ Itoh, H Hotani, M Inagaki. Filament formation of MSF-A, a mammalian septin, in mammary HMEC cells depends on interactions with microtubules. MOLECULAR BIOLOGY OF THE CELL. 2002. 13. 189A-189A
K Nagata, Izawa, I, M Inagaki. A decade of site- and phosphorylation state-specific antibodies: recent advances in studies of spatiotemporal protein phosphorylation. GENES TO CELLS. 2001. 6. 8. 653-664
Inada,H, Izawa,I, Nishikawa,M, Fujita,E, Kiyono,T, Takahashi, T.Momoi,T, Inagaki,M. Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD. J.Cell Biol. 2001. 155. 3. 415-425