2019 - 2022 Understanding in spatio-temporal regulation mechanism of thrombus formation and dissolution for realization of appropriate antithrombotic therapy
2017 - 2020 Vasa Vasorum in Abdominal Aortic Aneurysm
2016 - 2019 Various reguratory mechanisms of activated-platelet' memberane-based activation of fibrinolysis.
2017 - 2019 vasa vasorumの血流変動が腹部大動脈瘤の病態に及ぼす影響
2015 - 2018 The intrinsic roles of human PAI-1 in adipocyte differentiation and function with using patient-derived iPS cells.
2016 - 2018 活性化血小板膜を基盤とした血栓溶解活性発現の多様な調節機構の解析
2015 - 2017 疾患特異的iPS細胞を用いた脂肪細胞分化・機能に及ぼすヒトPAI-1の役割
2013 - 2016 Elucidation of intrinsic fibrinolytic activities potentiated vascular endothelial cells and its possibility in prophylaxis of thrombotic disease
2012 - 2015 Role of phosphatidylserine on activated platelets on tissue factor initiated blood coagulation
2012 - 2015 Generation of iPS cells from PAI-1 deficient patient and differentiation into mature cells
2010 - 2012 Imaging analysis of the role of newly proposed cell surface-associated fibrinolysis mechanism in the regulation of endothelial barrier function.
1987 - 1989 Mechanisms of the inhibition of t-PA by PAI-1
1987 - 1989 プラスミノ-ゲンアクチベ-タ-インヒビタ-によるt-PA阻害機序の研究
Regulation of fibrinolytic activity
Angiogenesis
Fibrinolysis & Tumor Growth
Analyses of the function and conformation of the proteins involved in the fibrinolytic system
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Papers (341):
Yuko Suzuki, Nitty S. Mathews, Hideto Sano, Nanami Morooka, Naoki Honkura, Tetsumei Urano. Real-Time Imaging of Platelet-Initiated Plasma Clot Formation and Lysis Unveils Distinct Impacts of Anticoagulants. Thrombosis and Haemostasis. 2025
Kanou S., Nakatani E., Urano T., Sasaki H., Inoue A., Hifumi T., Sakamoto T., Kuroda Y, MD, Tanaka Y., on behalf of, et al. Fibrinogen levels and Bleeding Risk in Adult Extracorporeal Cardiopulmonary Resuscitation: Multicenter Observational Study Subanalysis. Research and Practice in Thrombosis and Haemostasis (RPTH). 2025
Christopher D. Barret, Yuko Suzuki, Ernest E. Moore, Hunter B. Moore, Elizabeth R. Magino, Collin M. White, Halima Siddiqu, James G. Chandler, Angela Sauaia, Tetsumei Urano. A Novel Fibrinolysis Resistance Capacity Assay Can Detect Fibrinolytic Phenotypes in Trauma Patients. Thrombosis and Haemostasis. 2024
Tetsumei Urano, Yoshie Sano, Yuji Suzuki, Masahiko Okada, Hideto Sano, Naoki Honkura, Nanami Morooka, Matsuyuki Doi, Yuko Suzuki. Evaluation of thrombomodulin/thrombin activatable fibrinolysis inhibitor function in plasma using tissue-type plasminogen activator-induced plasma clot lysis time. Research and Practice in Thrombosis and Haemostasis. 2024. 8. 4. 102463-102463
A novel fibrinolysis resistance capacity assay successfully detected fibrinolytic phenotypes in trauma patients.
(Fibrinolysis down Under: Fundamental aspects and Translational opportunities 2024)
Impaired fibrinolysis resistant capacity causes hyper-fibrinolysis in DIC in APL: JALSG APL212 study
(2024)
E. Proposal for establishing guidance for diagnosis of rare bleeding disorders caused by dysfunction of fibrinolysis inhibitors.
(2024)
線溶抵抗活性の新規迅速測定法
(第46回日本血栓止血学会 2024)
Three Distinct Clot Lysis Assays to Detect Activities of PAI-1, TM/TAFI and a2 Antiplasmin: Their Applications to Assess TXA Necessity, PAI-1 Deficiency and Soluble TM Function in Plasma
(2024)
1981 - 1985 Hamamatsu University School of Medicine, Graduate course
1975 - 1981 Hamamatsu University School of Medicine Faculty of Medicine School of Medicine
Professional career (2):
PhD (Hamamatsu University School of Medicine)
MD (Hamamatsu University School of Medicine)
Work history (13):
2021/04 - 現在 十全オアシスクリニック院長
2021/04 - 現在 Shizuoka Public Health University
2021/04 - 現在 Hamamatsu University School of Medicine
2001/04 - 2021/03 Hamamatsu University School of Medicine Department of Physiology professor
2016/04 - 2020/03 Hamamatsu University School of Medicine
1991 - 2001 Hamamatsu University School of Medicine
1991 - 2001 Hamamatsu Univ. Sch. of Med. Associate Professor
1991/03 - 1991/04 Rigas Hospitalet Denmark Department of Clinical Laboratory (Dr. Sixtus Thorsen's laboratory) visiting scientist
1990/06 - 1991/02 Umea University, Sweden Department of Applied Chemistry (Dr. Tor Ny's Laboratory) Visiting Scientist
1987 - 1991 Hamamatsu University School of Medicine
1987 - 1991 Hamamatsu Univ. Sch. of Med. Assistant
1986 - 1988 University of Notre Dame Department of Chemistry (Dr. Francis J Castellino's laboratory) post doctoral fellow
1986 - 1988 Post doctoral fellow, Univ. of Notre Dame (USA)
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Committee career (14):
2021/09 - 現在 International Society of Thrombosis and Haemostasis Chairman of Fibrinolysis division of SSC
2016 - 現在 International Society of Thrombosis and Haemostasis Member of steering committee of the World Thrombosis Day
2015 - 現在 Asian Pacific Society of Thrombosis and Haemostasis, Council member & Treasurer
2010 - 現在 International Society of Fibrinolysis & Proteolysis council member
1996 - 現在 International Society of Thrombosis and Haemostasis member
1993 - 現在 International Society of Fibrinolysis & Proteolysis member
2018 - 2022/03 日本生理学会 理事
2015 - 2021/09 International Society of Thrombosis and Haemostasis Co-chairman of Fibrinolysis division of SSC
2012 - 2020/06 日本血栓止血学会 理事
2009 - 2013 International Society of Thrombosis and Haemostasis Co-chairman of Fibrinolysis division of SSC
1994 - 日本血液学会 評議員
1993 - 日本臨床血液学会 評議員
1992 - 日本血栓止血学会 評議員
1991 - 日本生理学会 評議員
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Awards (2):
2025/01 - Japanese Society of Thrombosis and Haemostasis Shosuke Okamoto Award
1993 - 斉藤奨励賞
Association Membership(s) (8):
American Society of Hematology
, International Society on Thrombosis and Haemostasis
, International Society Fibrinalysis and Proteolysis
, 日本静脈学会
, 日本臨床血液学会
, Japanese Society of Thrombosis and Haemostasis
, 日本血液学会
, 日本生理学会