Rchr
J-GLOBAL ID：200901061716641810   Update date: Mar. 25, 2024

Sakagami Hiroshi

サカガミ ヒロシ | Sakagami Hiroshi
Affiliation and department：
Meikai University School of Dentistry

About Meikai University School of Dentistry


Job title： Professor,Director, Meikai-Pharmaco-Medical Laboratory (MPL),Chairman, International Exchange Committe, School of Dentistry,Director, Media Center
Other affiliations (1)：
Homepage URL  (1)： http://www.meikai.ac.jp/dent/m-rio.html
Research field  (5)： Information networks ,  Oral medicine ,  Other ,  Pharmacology ,  Pharmaceuticals - health and biochemistry
Research keywords  (18)： Traditional Chinese Medicine ,  X-ray sensitivitiy ,  Chromone derivative ,  Search for neuroprotective substances ,  International communication capability ,  Anti-aging ,  Antioxidants ,  Hormesis ,  Anti-UV activity ,  Anti-HIV activity ,  Quantitative structure-actiivty relationship ,  Lignin-carbohydrate complex ,  Tumor-specificity ,  Synthetic compound ,  Polyphenol ,  Biochemistry ,  Dental Pharmacology ,  Applied Pharmacology
Research theme for competitive and other funds  (38)：
  • 2020 - 2023 Elucidation of selective cytotoxicity against malignant cells by chromone derivatives
  • 2020 - 2023 Development of minimally invasive therapy for oral cancer by hyperthermia with tumor-specific targeting magnetic nanoparticles
  • 2018 - 2021 Approach from the peripheral and central to the pain of tooth movement by orthodontic treatment
  • 2017 - 2020 Improvement of body function by underwater movement and influence on saliva aging marker
  • 2016 - 2019 Basic research of possibility of newly synthesized 3-styrylchromone derivatives as chemotherapeutic drugs against oral carcinoma
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Papers (1,408)：
  • MASAKI MORIKAWA, SHUNSUKE UEHARA, AKIHIRO YOSHIDA, HIROSHI SAKAGAMI, YOSHIKO MASUDA. Photodynamic Therapy With Resveratrol and an Nd:YAG Laser forEnterococcus faecalisElimination. In Vivo. 2024. 38. 2. 559-566
  • Ahmed Abdullah Al Awadh AAA, Sakagami H, Amano S, Ahmed M, Sayed AM, Abouelela ME, Alhasaniah AH, Aldabaan N, Refaey MS, Abdelhamid RA, et al. In vitro cytotoxicity of Withania somnifera (L.) roots and fruits on oral squamous cell carcinoma cell lines: a study supported by flow cytometry, spectral, and computational investigations. Front. Pharmacol. 2024. 15
  • Swagatika Das, Praveen K. Roayapalley, Hiroshi Sakagami, Naoki Umemura, Dennis K. J. Gorecki, Mohammad Hossain, Masami Kawase, Umashankar Das, Jonathan R. Dimmock. Dimeric 3,5-Bis(benzylidene)-4-piperidones: Tumor-Selective Cytotoxicity and Structure-Activity Relationships. Medicines. 2024. 11. 1. 3-3
  • Suzuki R, Shirataki Y, Tomomura A, Bandow K, Sakagami H, Tomomura M. Isolation of Pro-Osteogenic Compounds from Euptelea polyandra That Reciprocally Regulate Osteoblast and Osteroclast Differentiation. Int. J. Mol. Sci. 2023. 24
  • Mohamed A. A. Orabi, Esam A. Orabi, Ahmed Abdullah Al Awadh, Mohammed Merae Alshahrani, Basel A. Abdel-Wahab, Hiroshi Sakagami, Tsutomu Hatano. New Megastigmane and Polyphenolic Components of Henna Leaves and Their Tumor-Specific Cytotoxicity on Human Oral Squamous Carcinoma Cell Lines. Antioxidants. 2023. 12. 11. 1951-1951
ｍore...
MISC (520)：
  • Hiroshi Sakagami, Masanori Fujisawa, Masahiko Kobayashi, Fumiko Narumi, Yuji Miyazaki, Kitetsu Shin, Toshikazu Yasui, Motohiko Nagayama, Shu Fujiwara, Izumi Den, et al. The importance of international communication skills-Student/Faculty Exchange Program with University of the Western Cape. New Food Industry. 2024. 66. 4. 229-241
  • 坂上宏, 千葉直樹. スターターとデベロッパー:天命「を知り「極める」. New Food Industry. 2024. 66. 1. 43-49
  • 坂上 宏, 魚田 慎, 天野 滋, 大高 祐聖, 井澤 真希, 鬼頭 慎司, 須永 克佳, 鈴木 龍一郎, 小川 由香里, 上田 大輔, et al. 3大学連携プロジェクト: コロナ禍における安全で持続性のあるUVC保護物質の探索. New Food Industry. 2023. 65. 12. 705-712
  • Lopez-Ayuso CA, Shin Uota, Acra AM, Kobayashi M, Acosta-Torres LS, Garcia-Contreras R, Sakagami H. Bridging Mexico and Japan: Exploring the Significance of Research Stays. New Food Industry. 2023. 65. 11. 664-671
  • 小田慎太郎, 猪俣恵, 坂上宏. 歯周病とヒト口腔ウイルス叢の関連性. New Food Industry. 2023. 65. 4. 241-244
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Patents (12)：
  • ヒト免疫不全ウイルス不活性化剤
  • 単純ヘルペス不活性化剤
  • Newly synthesized tannin derivatives
  • 新規タンニン誘導体
  • ポリカフェノールの新規用途
ｍore...
Books (85)：
  • Biological Efficacy of Natural and Chemically Modified Products against Oral Inflammatory Lesions
    Lightning Source UK Ltd 2019 ISBN:9783038979920
  • 入門テキスト はじめての情報・メディア・コミュニケーション リテラシー
    科学評論社 2019 ISBN:9784297104917
  • Temas selectos de biomedicina en Ciencias de la Salud
    Capitulo I Area Odontologia, Efecto citotoxico de las nanoparticulas de TiO2 en cultivo de celulas orales, p31-42, 2017 2017 ISBN:9786079426996
  • Biological Activities and Action Mechanisms of Licorice Ingredients
    INTECH 2017 ISBN:9789535151951
  • Therapeutic potential of solubilized nanolignin against oral diseases.
    Elsevier 2017 ISBN:9780323477208
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Lectures and oral presentations  (13)：
  • Identification of potent anti-oral cancer (Part I), anti-HIV (Part II) and anti-UVC entities (Part III) among hundreds of natural and synthetic polyphenols, and anti-inflammation activity of alkaline extract of plants (Addendum)
    (Invited Lecture at the 60th anniversary of UAEM Dental School 2024)
  • 抗酸化剤によるボルテゾミブ誘発性神経障害に対する保護効果
  • 2-Arylazolylchromonesと2-Triazolylchromonesの定量的構造-細胞傷害性相関解析
    (第141回日本薬理学会関東部会 2019)
  • 2-スチリルクロモン誘導体の定量的構造-細胞傷害性相関解析
    (第141回日本薬理学会関東部会 2019)
  • X線照射誘発性PC12神経細胞傷害に及ぼすNGFの保護効果
    (第141回日本薬理学会関東部会 2019)
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Works (4)：
  • Effect of Sodium benzylidene ascorbate on transplanted tumor in nude mice
    2002 - 2003
  • Antiviral activity and apoptosis-inducing activity of tannin and related compounds
    1989 - 2001
  • Antitumor activity of sodium benzylidene ascorbate
    1997 - 1998
  • Anti-HIV Chumon immunodeficiency virus activity
    1989 - 1991
Education (4)：
  • 1975 - 1980 The University of Tokyo Graduate School of Pharmaceutical Sciences
  • - 1980 The University of Tokyo Graduate School, Division of Pharmaceutical Sciences
  • 1970 - 1974 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmacy
  • - 1974 The University of Tokyo Faculty of Pharmaceutical Science
Professional career (2)：
  • (BLANK) (The University of Tokyo)
  • (BLANK) (Showa University)
Work history (18)：
  • 2017/04 - 現在 Meikai University Research Institute of Odontoloty (M-RIO) Director
  • 2017/04 - 現在 Meikai University School of Dentistry Full-time professor
  • 2014/04 - 現在 Asahi University
  • 2014/04 - 現在 Meikai University
  • 1999/04 - 2017/03 Meikai University School of Dentistry Pharmaco-Medical Laboratory Head
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Committee career (9)：
  • 2020/03 - 現在 Medicines Editor-in-Chief
  • 2016/04 - 現在 New Food Industry Editorial Board Member
  • 2003 - 現在 歯科基礎医学会 評議員
  • 1998/04 - 現在 薬理学会 評議員
  • 1992 - 現在 In Vivo Editorial Board Member
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Awards (1)：
  • 2020/02 - Bioscience, Biotechnology, and Biochemistry (BBB) Paper Award, Most-cited Review Award Three new flavonoids, proanthocyanidin, and accompanying phenolic constituents from Feijoa sellowiana
Association Membership(s) (5)：
IADR ,  日本生薬学会 ,  歯科基礎医学会 ,  薬理学会 ,  IADR
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