Satomura Kazuhito

2020 - 2023 側方漏光性光ファイバーを応用した口腔癌に対する新規光線力学的免疫温熱療法の確立

2021 - 2022 Elucidation of the function of platelet aggregation factor podoplanin in distant metastasis of oral cancer

2019 - 2022 Establishment of a new photodynamic diagnostic method focusing on abnormal porphyrin metabolism in oral cancer cells and trial for clinical application

2016 - 2022 Involvement of anesthetics in axon guidance of regenerating neurons

2017 - 2020 Possibility of new tissue regeneration therapy utilizing the transdifferentiation ability (differentiation plasticity) of mature functional cells

2017 - 2020 Development of 3D tissue cinstruct fabricated from dental pulp stem cell

2017 - 2020 Development of photodynamic diagnosis and intra-operative navigation system for oral cancer using 5-ALA

2016 - 2020 Inhibition of distant metastasis of oral cancer by functional control of the platelet aggregation factor podoplanin

2016 - 2019 Possibility of establishing a new oral cancer treatment applying the radioprotective and antitumor effects of melatonin

2016 - 2019 Development of a new minimally invasive oral mucous membrane inspection method applying optical coherence tomography

2016 - 2018 高齢者の観血的歯科治療安全チェックリストの作成とその評価

2015 - 2018 Establishment of a new method for healing of tooth extraction by immediate implantation of extracted tooth pulp tissue

2015 - 2017 Metreleptin promotes wound healing in the skin and oral mucosa

2014 - 2017 Development of minimum-invasive oral cancer therapy using photo-immunotherapy targeted on cancer stem cells

2014 - 2017 A new induction method for the controlled differentiation of human iPS cells using frozen sections

2014 - 2017 Influence of oral bacteria / fungus-producing acetaldehyde on oral burning mouse syndrome and establishment of therapy

2013 - 2016 Neurogenic differentiation potential of mouse osteoblastic cell line

2013 - 2016 Possible application of 405-nm blue light irradiation for the treatment and the prevention of oral candidiasis

2013 - 2016 光線免疫療法を応用した低侵襲口腔癌治療の開発

2013 - 2016 A study of topographic anatomy in preexisting lymph vessels of oral tongue in conjunction with depth of invasion and metastasis

2013 - 2015 Leptin Promotes Wound Healing in the Skin and Oral Moucosa

2012 - 2015 Preventive effect of melatonin against radiation-induced mucosal injury

2012 - 2015 Leptin promotes wound healing in the oral mucosa

2012 - 2014 Analysis of pathogenesis and pathophygiological distinction of leukoplakia and development a new method of estimation of malignant alteration focused on calcium sensing receptor

2011 - 2013 The connection between the periodicity incremental lines of dentin and the secretion rhythm of melatonin of the signaling molecules of biological clock

2011 - 2013 The development of the cementum / periodontal membrane reproduction type implant with induced pluripotent stem cells derived from oral mucosa

2011 - 2013 A new induction method for the controlled differentiation of human iPS cells using frozen sections

2011 - 2012 ヒト口腔粘膜由来iPS細胞の効率的分化誘導法の確立と分化誘導因子の網羅的解析

2010 - 2012 A physiologic role of the melatonin in the formation and the growth of the tooth and the regenerative medicine of the tooth

2010 - 2012 The effects ofanesthetics onperipheral nerve regeneration

2009 - 2011 Development of the melatonin treatment which aimed at shortening of the recovery period after operation related bone tissue.

2007 - 2008 Induced Odontogenic Differentiation of Bane Marrow Strome-derived Stem Cells and Their Possiblity for Teeth Regeneration

2006 - 2007 エピジェネティクスを応用した幹細胞の創製とそれを用いた再生医療実現の可能性

2005 - 2006 青色レーザーの歯周病原菌増殖抑制効果を利用した新規歯周病治療法の開発

2004 - 2006 Mechanisms of multipotency of adult stem cells derived from bone marrow stroma and peripheral blood and their application for regenerative medicine

2004 - 2005 末梢血中に存在する体性幹細胞の分離・同定とその再生医療への応用の可能性

2003 - 2004 Electrophysiological analysis for neurons derived from bone marrow stromal cells

2002 - 2003 Fabrication of bioresorbable porous ceramics for bone regeneration and its bone reconstruction using transplantation with the blood vessel pattern

2002 - 2003 Isolation of somatic stem cells from bone marrow stroma and peripheral blood, and their application for tissue regeneration

2002 - 2003 口腔癌の蛍光診断および光線力学治療の開発とその細胞生物学的検討

2001 - 2002 Role of Leptin in Endochondral Ossification

2000 - 2001 Development of pedicled plastic bone flap using cultured osteogenic cells and its application for the reconstruction of mandibular bone defect

2000 - 2001 多孔性ハイドロキシアパタイト含有ポリ-L-乳酸メンブレンの開発とその特性

1999 - 2000 Relationship of cellular adhesive molecules and angiogenesis with oral squamous cell carcinoma.

1998 - 1999 高骨形成能を有する骨髄間質細胞の選別・分離とその骨欠損部再建への応用

1993 - 1993 骨・軟骨両者の分化可能な骨髄器官培養系の確立とその分化過程の細胞生物学的解析

1991 - 1992 Biological and clinical study on regulation of gene expression in osteoblast and its osteogenesis

エピジェネティクス・分化転換を応用した再生医療

成体幹細胞の増殖・分化機構の解明と再生医療への応用

歯の再生に関する研究

歯胚を用いた上皮・間葉間相互作用

骨髄間質細胞の分化機構の解明

Regenerative medicine using epigenetics and transdifferentiation

Isolation of adult stem cells and their application to regenerative medicine

Study of tooth regeneration

Study on epithelial-mesenchymal interaction in tooth clevelopment

Study on differentiation mechanisms of bone marrow stromal cells.