Rchr
J-GLOBAL ID:200901066329386138
Update date: Oct. 23, 2024
Suetsugu Shiro
スエツグ シロウ | Suetsugu Shiro
Affiliation and department:
Job title:
Professor
Research field (4):
Medical biochemistry
, Cell biology
, Functional biochemistry
, Structural biochemistry
Research keywords (20):
Artificial Intelligence
, Extracellular Vesicles
, F-BAR domain
, I-BAR domain
, BAR domain
, Cell Motility
, metastasis
, invasion
, cytoskeleton
, Plasma membrane
, Signal Transduction
, Proteins
, Membrane Deformation
, phosphoinositides
, cell migration machinaries
, lipids
, cancer
, endocytosis
, intracellular signaling
, actin cytoskeleton
Research theme for competitive and other funds (33):
- 2024 - 2027 細胞突起の多様性に起因する細胞外小胞の機能多様性の分子機構
- 2024 - 2026 細胞外小胞のクライオ電子顕微鏡解析に向けた分類と精製方法の確立
- 2021 - 2026 Elucidating the fundamental mechanism of platelet biogenesis and its medical application
- 2020 - 2023 The assembly mechanisms of the BAR domain proteins for physiological functions
- 2020 - 2023 Childhood nutrition-dependent myelin structure and its effects on psychiatric symptoms
- 2021 - 2023 1次元細胞運動における核と細胞膜の協調移動機構の解明
- 2017 - 2020 The membrane shaping by the ankyrin repeat domains
- 2017 - 2020 The BAR domains that function in the protrusive membranes
- 2015 - 2020 Morphology and characteristics of membranes directed by lipoquality
- 2017 - 2019 数理解析を目指した超解像顕微鏡によるシグナル伝達タンパク質の実濃度測定
- 2016 - 2019 Mechanism of novel secretory vesicle formation by lipid membrane binding I-BAR proteins
- 2017 - 2019 アンキリンリピートによるBARドメイン様の脂質膜の形態制御機構の研究
- 2017 - 2019 細胞膜突出構造におけるBARタンパク質の集合機構とその生理機能
- 2015 - 2019 リポクオリティが演出する膜の形態と性質
- 2017 - 2018 数理解析を目指した超解像顕微鏡によるシグナル伝達タンパク質の実濃度測定
- 2015 - 2017 タンパク質ポリマー形成による動的膜形態形成の直接可視化による解明
- 2014 - 2017 Formation mechanisms for cellular protrusions and their physiological functions
- 2015 - 2016 タンパク質ポリマー形成による動的膜形態形成の直接可視化による解明
- 2014 - 2016 細胞膜突出構造の膜形態制御機構と生理機能
- 2013 - 2015 細胞がん化における細胞形態変化と代謝、細胞増殖の関連の研究
- 2011 - 2011 浸潤突起における膜構造構築とシグナル分子の集積機構
- 2008 - 2010 Multiple layers of regulatory machineries for actin cytoskeleton at the leading edge
- 2005 - 2009 The roles of phosohoinositides in transportsome
- 2005 - 2009 Migration of cancer cells and its regulatory mechanism
- 2005 - 2007 細胞移動先端におけるアクチン細胞骨格制御機構の解明
- 2004 - 2006 イノシトールリン脂質によるWASPファミリー蛋白質の活性抑制
- 2004 - 2004 MAPキナーゼシグナルと癌細胞の運動におけるアクチン重合制御
- 2003 - 2004 WASPファミリータンパク質の脳神経系の形態形成シグナルにおける役割
- 2000 - 2004 Signaltransduction of cytoskeleton and cell movement
- 1997 - アクチン細胞骨格の制御に関する研究
- 脂質二重膜(細胞膜)の形態制御の研究
- Regulation shape formation of cell membrane
- Study for Regnlation of Actin Cytoskelton
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Papers (137):
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Hooi Ting Hu, Tamako Nishimura, Hiroki Kawana, Rachelle Anne So Dante, Gisela D’Angelo, Shiro Suetsugu. The cellular protrusions for inter-cellular material transfer: similarities between filopodia, cytonemes, tunneling nanotubes, viruses, and extracellular vesicles. Frontiers in Cell and Developmental Biology. 2024. 12
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Manuela Basso, Alessandro Gori, Caterina Nardella, Mari Palviainen, Marija Holcar, Ioannis Sotiropoulos, Sylwia Bobis-Wozowicz, Vito G D'Agostino, Elena Casarotto, Yari Ciani, et al. International Society for Extracellular Vesicles Workshop. QuantitatEVs: multiscale analyses, from bulk to single extracellular vesicle. Journal of extracellular biology. 2024. 3. 1
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Yosuke Senju, Shiro Suetsugu. Membrane Proteins: Function, Structure, and Dynamics. Membranes. 2023. 13. 12
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Pei Fang Sim, Min Fey Chek, Nhung Thi Hong Nguyen, Tamako Nishimura, Takehiko Inaba, Toshio Hakoshima, Shiro Suetsugu. The SH3 binding site in front of the WH1 domain contributes to the membrane binding of the BAR domain protein endophilin A2. Journal of biochemistry. 2023. 175. 1. 57-67
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Rim Bouslama, Vincent Dumont, Sonja Lindfors, Lassi Paavolainen, Jukka Tienari, Harry Nisen, Tuomas Mirtti, Moin A Saleem, Daniel Gordin, Per-Henrik Groop, et al. Phosphorylation of PACSIN2 at S313 Regulates Podocyte Architecture in Coordination with N-WASP. Cells. 2023. 12. 11
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MISC (38):
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川名 裕己, 末次 志郎, 青木 淳賢. 脂質場の変動によるBAR domainタンパクの局在変化の解析. 日本細胞生物学会大会講演要旨集. 2017. 69回. 63-63
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Y. Itoh, K. Kida, K. Hanawa-Suetsugu, S. Suetsugu. Yeast Ivy1p Is a Putative I-BAR-domain Protein with pH-sensitive Filament Forming Ability in vitro (vol 41, pg 1, 2016). CELL STRUCTURE AND FUNCTION. 2016. 41. 1. 21-21
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Y. Itoh, K. Kida, K. Hanawa-Suetsugu, S. Suetsugu. Yeast Ivy1p is a putative I-BAR-domain protein with pH-sensitive filament forming ability in vitro. MOLECULAR BIOLOGY OF THE CELL. 2016. 27
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Tadaomi Takenawa, Shiro Suetsugu. WASP/WAVE proteins: expanding members and functions & The role of ploidy variation on cellular adaptation Preface. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. 2013. 24. 4. 257-257
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SENJU Yosuke, TACHIKAWA Masashi, MOCHIZUKI Atsushi, SUETSUGU Shiro. Acute regulation of cell surface area by the balance between flattening and endocytosis of caveolae. 日本細胞生物学会大会要旨集. 2013. 65th
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Books (1):
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Plasma Membrane Shaping
Academic Press Inc 2022 ISBN:9780323899116
Lectures and oral presentations (117):
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細胞突起の切断による新機能
(2024年生体運動研究合同班会議 2024)
-
クローン化マクロファージの貪食能の比較
(第46回分子生物学会年会 2023)
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I-BARタンパク質による細胞突起の細胞外小胞形成における役割
(第46回日本分子生物学会年会 2023)
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The BAR domain assembly and the extracellular vesicle formation from cellular protrusions
(第61回日本生物物理学会年会 2023)
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細胞膜に由来する細胞外小胞を介した細胞増殖の促進と細胞外マトリックスの関与
(第10回日本細胞外小胞学会学術集会 2023)
more...
Education (3):
- 1999 - 2002 The University of Tokyo
- 1997 - 1999 The University of Tokyo
- 1993 - 1997 The University of Tokyo Faculty of Science
Professional career (1):
- Ph.D. (The University of Tokyo)
Work history (8):
- 2021/04 - 現在 Nara Institute of Science and Technology Center for Digital Green-innovation Professor
- 2019/05 - 現在 Nara Institute of Science and Technology Data Science Center Professor
- 2018/04 - 現在 Nara Institute of Science and Technology Division of Biological Science, Graduate School of Science and Technology Professor
- 2014/02 - 2018/03 Nara Institute of Science and Technology Graduate School of Biological Sciences Professor
- 2009/07 - 2014/01 The University of Tokyo Institute of Molecular and Cellular Biosciences Associate Proffessor
- 2007/01 - 2009/06 The University of Tokyo Institute of Molecular and Cellular Biosciences Lecturer
- 2002/04 - 2006/12 The University of Tokyo The Institute of Medical Science Reseach Associate
- 1999/04 - 2002/03 JSPS Research Fellowship for Young Scientists
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Committee career (3):
- 2014 - 現在 日本生化学会 評議員
- 2004 - 現在 日本細胞生物学会 評議員
- 2018/06 - 2022/06 日本細胞生物学会 理事
Awards (4):
- 2015/02 - 風戸研究奨励会 風戸賞
- 2013/09 - 日本生化学会 奨励賞
- 2012/04 - 文部科学省 若手科学者賞
- 2011/06 - FEBS FEBS letters young investigator award
Association Membership(s) (9):
American Society for Cell Biology
, THE BIOPHYSICAL SOCIETY OF JAPAN
, THE JAPANESE SOCIETY OF MICROSCOPY
, THE JAPANESE CONFERENCE ON THE BIOCHEMISTRY OF LIPIDS
, 日本癌学会
, 日本神経科学会
, 日本分子生物学会
, 日本生化学会
, 日本細胞生物学会
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