Rchr
J-GLOBAL ID：200901068419432506
Update date: Mar. 30, 2024
Tanaka Junya
タナカ ジュンヤ | Tanaka Junya
Affiliation and department：
Job title：
Professor
Homepage URL (1)：
http://www.m.ehime-u.ac.jp/school/physiology1/index.html
Research field (2)：
Cell biology
, Neuroscience - general
Research keywords (7)：
behavior
, microglia
, sepsis
, tumor immunity
, 分子・細胞神経科学
, Molecular and Cellular Neuroscience
, Neurocytology
Research theme for competitive and other funds (42)：
- 2020 - 2022 Heterosexual communication and microglial synaptic pruning
- 2015 - 2019 Development of Oct-3/4 targeting drug for malignant glioma treatment
- 2016 - 2018 Toll様受容体を介す熱性痙攣と続発性てんかんの病態解明と新規分子標的療法の開発
- 2015 - 2017 Therapeutic effects to neuropathic pain by inhibition of STAT1 phosphorization
- 2014 - 2017 Expression of oxytocin receptor in a rat stroke model
- 2015 - 2017 Involvement of microglial cells in the sleep/wake cycle
- 2013 - 2016 High mobility group box 1 enhanced febrile seizures and acquired epilepsy in a rodent model of infantile febrile seizures
- 2012 - 2014 Activated microglia in a rat stroke model express NG2 proteoglycan in peri-infarct tissue through the involvement of TGF-beta1
- 2011 - 2013 Protective effects of Ketone-bodies against demyelinating disease
- 2011 - 2012 Determination of cell type(s) that should be transplanted into lesion core of the brain for better outcome
- 2010 - 2012 Mechanism and prevention strategy for mesial temporallobe epilepsy following febrile status convulsion
- 2010 - 2012 Multipotential stem cell-like nature of bone marrow-derived macrophages accumulated in lesion core of acute and severe brain injuries.
- 2009 - 2010 神経膠腫細胞浸潤におけるArf6依存性および非依存性の意義
- 2006 - 2007 The effects of SOCS3 on neural stem cell fate and feasibility of the SOCS3-overexpressingneural stem cells for stake therapy
- 2005 - 2006 トランスジェニックマウスを用いたマイクログリアによる脳損傷修復システムの解明
- 2004 - 2005 Molecular mechanism of cerebral ischemia through Jak-Stat signaling
- 2004 - 2005 Development of novel therapeutic means to regenerating spinal cord injury using microglia/macrophages
- 2003 - 2004 革命的脊髄損傷治療法の開発:骨髄細胞あるいは末梢血から中枢神経組織を作る
- 2002 - 2004 エリスロポエチン由来ペプチドの神経細胞死抑止効果と作用機構解析
- 2001 - 2003 The role of sex steroid on the generation of sex differences in the brain development with special attention to androgen.
- 2000 - 2002 Comprehensive analyses of blood circulation, oxygen transport and neural activity in microcirculatory level of brain
- 2000 - 2001 L-セリンとグリシンの神経細胞死抑止機序解明と神経疾患治療への応用可能性の検討
- 1999 - 2001 Protective effects of erythropoietin on ischemic brain
- 1999 - 2000 Development of factors that prevent secondary neuronal degeneration
- 1998 - 2000 Protection of the ischemic brain by a new prostaglandin I2 analog clinprost
- 1998 - 1999 PURIFICATION AND CHARACTERZATION OF GLIA-DERIVED NEUROPROTECTIVE FACTORS
- 1993 - 1994 Interaction of annexins with membrane skeletal proteins in brain
- 1993 - 1994 Molecular Mechanism of the differentiation of smooth muscle cells
- 1993 - 1993 細胞骨格系による中枢シナプス機能発現の分子機作に関する研究
- 1993 - 1993 がん細胞に特有な細胞接着構造の分子構築の解明
- 1992 - 1993 Analyzes of dynamic molecular organization of the membrane skeleton
- 1992 - 1992 細胞骨格系による中枢シナプス機能発現に分子機作に関する研究
- 1991 - 1992 Interaction between ion channels and membrane skeleton
- 1991 - 1992 Analysis for the Expressional Change of Caldesmon Isoforms during Phenotyptic Modulation of Smooth Muscle Cells
- 1991 - 1991 癌細胞動的接着部の分子構築の解析
- 1989 - 1991 A New Method for the Analyses of Cytoskeletal and Their Related Proteins
- 1990 - 1990 がん細胞接着部における細胞接着因子と細胞膜裏打ち構造の役割
- 1988 - 1990 Role of Cytoskeletal System and its Regulation by Ca^<2+> in Exocytosis
- 中枢神経系における細胞間相互作用
- グリア細胞の発生と分化
- Cellular Interactions in the Central Nervous System
- Development and differentiation of glial cells
Show all
Papers (199)：
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Yoshihiro Ohtsuka, Satoshi Suehiro, Akihiro Inoue, Takanori Ohnishi, Masahiro Nishikawa, Daisuke Yamashita, Hajime Yano, Mohammed E Choudhury, Saya Ozaki, Oltea Sampetrean, et al. Berberine as a potential enhancer for 5-ALA-mediated fluorescence in glioblastoma: increasing detectability of infiltrating glioma stem cells to optimize 5-ALA-guided surgery. Journal of neurosurgery. 2024. 1-11
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Haruna Takeda, Yoshihiro Nakajima, Teruaki Yamaguchi, Itaru Watanabe, Shoko Miyoshi, Kodai Nagashio, Hiroki Sekine, Hozumi Motohashi, Hajime Yano, Junya Tanaka. The anti-inflammatory and anti-oxidative effect of a classical hypnotic bromovalerylurea mediated by the activation of NRF2. Journal of biochemistry. 2023. 174. 2. 131-142
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Yuki Nishikawa, Mohammed E Choudhury, Kanta Mikami, Matsuura Taisei, Madoka Kubo, Masahiro Nagai, Satoru Yamagishi, Tomomi Doi, Manami Hisai, Haruto Yamamoto, et al. Anti-inflammatory effects of dopamine on microglia and a D1 receptor agonist ameliorates neuroinflammation of the brain in a rat delirium model. Neurochemistry international. 2023. 105479-105479
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Haruna Takeda, Yumiko Yoshimura, Masahiro Takagi, Arisa Sato, Nanako Kihara, Mohammed E. Choudhury, Hajime Yano, Junya Tanaka. Bromovalerylurea modulates GABAA receptor-mediated inhibitory neurotransmission while inducing sleep. Biochemical and Biophysical Research Communications. 2023. 638. 176-183
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Mohammed E Choudhury, Saya Ozaki, Noriyuki Miyaue, Taisei Matsuura, Kanta Mikami, Afsana Islam, Madoka Kubo, Rina Ando, Hajime Yano, Takeharu Kunieda, et al. Chloride Intracellular Channel Protein 2 Promotes Microglial Invasion: A Link to Microgliosis in the Parkinson's Disease Brain. Brain sciences. 2022. 13. 1
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MISC (109)：
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Saya Ozaki, Kanta Mikami, Takeharu Kunieda, Junya Tanaka. Chloride Intracellular Channel Proteins (CLICs) and Malignant Tumor Progression: A Focus on the Preventive Role of CLIC2 in Invasion and Metastasis. Cancers. 2022. 14. 19
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Mohammed E. Choudhury, Kazuya Miyanishi, Haruna Takeda, Junya Tanaka. Microglia and the Aging Brain: Are Geriatric Microglia Linked to Poor Sleep Quality?. International Journal of Molecular Sciences. 2021. 22. 15. 7824-7824
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Mohammed E. Choudhury, Yuka Kigami, Junya Tanaka. Dual roles of microglia in the basal ganglia in Parkinson’s disease. International Journal of Molecular Sciences. 2021. 22. 8
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武田遥奈, 吉村由美子, 中島芳浩, 山口輝昌, 佐藤安理沙, 木原奈那子, ME Choudhury, 矢野元, 田中潤也. ブロモバレリル尿素の睡眠作用・抗炎症作用の解析. 日本生理学雑誌(Web). 2021. 83. 1
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Tomoyoshi Sanada, Afsana Islam, Teppei Kaminota, Yui Kirino, Reina Tanimoto, Hana Yoshimitsu, Hajime Yano, Yosuke Mizuno, Masahiro Okada, Souhei Mitani, et al. Elevated exosomal lysyl oxidase like 2 is a potential biomarker for head and neck squamous cell carcinoma. Laryngoscope. 2020. 130. 5. E327-E334
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Patents (7)：
Education (2)：
- - 1986 Osaka University Faculty of Medicine Medical School
- - 1986 Osaka University Faculty of Medicine
Professional career (1)：
Committee career (4)：
- 2020/10 - 現在 The Japanese Society for Neurochemistry councilor
- 2004 - 現在 日本病態生理学会 理事
- 1999 - 現在 日本生理学会 評議員
- 2007 - 2020/03 日本生理学会 理事
Association Membership(s) (3)：
THE JAPANESE SOCIETY FOR NEUROCHEMISTRY
, 日本病態生理学会
, 日本生理学会
