Rchr
J-GLOBAL ID:200901069932394942
Update date: Mar. 13, 2026
Takahashi Keisuke
タカハシ ケイスケ | Takahashi Keisuke
Affiliation and department:
Job title:
Associate Professor
Homepage URL (1):
https://www.toho-u.ac.jp/phar/index.html
Research field (1):
Pharmaceuticals - chemistry and drug development
Research keywords (2):
有機化学
, Organic chemstry
Research theme for competitive and other funds (15):
- 2023 - 2026 Synthesis of guanidine alkaloids based on palladium catalyzed cyclization-carbonylation reactions.
- 2018 - 2021 Synthetic studies of alkaloids possessing iNOS inducing activities
- 2016 - 2019 Improvement of medaka embryo toxicity assay by a novel pulsed power electroporation system
- 2015 - 2018 Development of new palladium catalyzed reactions utilizing the characteristic property of the ligand : switching of reaction pathway
- 2013 - 2016 Synthetic Study of Tirandamycins
- 2013 - 2016 Efficient Synthesis of Natural Products Useful for Drug Discovery Based on Innovative Synthetic Methodologies
- 2012 - 2014 ワンポット連続型複素環状化合物合成法の開発と創薬リード天然物の合成研究
- 2011 - 2012 Synthetic Study of Glutamate Receptor Antagonistic Natural Product Based on C-H Amination Reaction
- 2010 - 2012 Efficient Synthesis of Biologically Active Natural Products Useful for Drug Discovery
- 2009 - 2010 Development of new synthetic methodology based on Conia-ene type cyclization
- 2007 - 2009 Efficient Synthesis of Natural Products Having Intriguing Biological Activities Useful for Drug Discovery
- 2007 - 2008 Synthetic Studies of Natural Amino Acids ; Selective Agonists and Antagonist of Glutamate Recepters
- 2004 - 2007 α-ケトエステルを基質とする効率的置換クエン酸不斉構築法の開発
- 2000 - 生理活性天然物の全合成研究
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Papers (54):
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Takuya Tsukamoto, Keisuke Takahashi, Natsuki Murase, Kyoka Someya, Fujino Sakata, Tianci Yue, Taichi Kusakabe, Keisuke Kato. Synthesis of (-)-Monanchoradin A and (-)-Crambescin A2 392 Based on a Cyclization-Carbonylation-Cyclization Cascade. Organic letters. 2024. 26. 42. 9011-9016
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Keyue Xu, Miyuki Shimizu, Toma Yamashita, Mako Fujiwara, Shunya Oikawa, Guanghan Ou, Naho Takazakura, Taichi Kusakabe, Keisuke Takahashi, Keisuke Kato, et al. Inhibitory mechanisms of docosahexaenoic acid on carbachol-, angiotensin II-, and bradykinin-induced contractions in guinea pig gastric fundus smooth muscle. Scientific reports. 2024. 14. 1. 11720-11720
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Keisuke Obara, Aina Ichimura, Taichi Arai, Mako Fujiwara, Miho Otake, Nana Yamada, Kento Yoshioka, Taichi Kusakabe, Keisuke Takahashi, Keisuke Kato, et al. Platelet-activating factor contracts guinea pig esophageal muscularis mucosae by stimulating extracellular Ca2+ influx through diltiazem-insensitive Ca2+ channels. Journal of pharmacological sciences. 2024. 154. 4. 256-263
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Tianci Yue, Taichi Kusakabe, Takuya Tsukamoto, Keisuke Takahashi, Shoko Kikkawa, Isao Azumaya, Keisuke Kato. Cyclization-Carbonylation of 2-Alkynyl Primary Benzamides using p-Benzoquinone under Neutral Conditions. The Journal of organic chemistry. 2024. 89. 6. 3977-3986
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Keisuke Takahashi, Shunya Kudo, Kiharu Kawamura, Taichi Kusakabe, Shoko Kikkawa, Isao Azumaya, Keisuke Kato. Synthesis of the Proposed Structure of Mohangic Acid C. Organic Letters. 2022. 24. 18. 3416-3420
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MISC (44):
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池中良徳, 一瀬貴大, NIMAKO Collins, 中山翔太, 平野哲史, 市川剛, 加藤恵介, 高橋圭介, 長谷川浩, 平久美子, et al. ネオニコチノイド系殺虫剤の曝露実態の解明と毒性評価. Journal of Toxicological Sciences. 2019. 44. Suppl. S53-S53
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山口明美, 平野将司, 河野晋, 石橋弘志, 高橋圭介, 加藤恵介, 内田雅也, 有薗幸司, 冨永伸明. メダカ初期胚を用いたネオニコチノイドと代謝物の発生影響評価. 日本内分泌かく乱化学物質学会研究発表会要旨集. 2017. 20回. 64-64
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IKENAKA Yoshinori, KATO Keisuke, TOHYAMA Chiharu, ISHIZUKA Mayumi, MIYABARA Yuichi, ICHISE Takahiro, YAGIHASHI Mio, NAKAYAMA Shouta, MIZUKAWA Hazuki, TAIRA Kumiko, et al. Estimation of the exposure level of neonicotinoid pesticide for infant. Annual Meeting of the Japanese Society of Toxicology. 2017. 44. 0. O-20
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小嶺敬太, 野村祐介, 高橋圭介, 石原淳, 畑山範. N-Me-Welwitindolinnone C isothiocyanateの全合成. 天然有機化合物討論会講演要旨集(Web). 2015. 57th
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小嶺敬太, 野村祐介, CYRIL Pieri, 高橋圭介, 石原淳, 畑山範. N-Me-Welwitindolinone C isothiocyanateの合成研究. 有機合成化学セミナー講演予稿集. 2014. 31st
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Books (1):
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天然物合成で活躍した反応 実験のコツとポイント
化学同人 2011
Lectures and oral presentations (5):
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グルタミン酸受容体作用性天然物の合成研究
(有機合成化学総合講演会 ( 2011)
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エングレリン A の全合成
(第37回反応と合成の進歩シンポジウム 2011)
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C-Hアミノ化を基盤とするカイトセファリンの全合成研究
(第53回天然有機化合物討論会 2011)
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kaitocephalinの合成研究
(日本薬学会第130年会 2010)
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カイトセファリンの全合成
(日本薬学会第132年会 2010)
Works (5):
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C-Hアミノ化反応を活用するグルタミン酸受容体アンタゴニスト活性天然物の合成研究
2011 - 2013
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Conia-ene型環化を鍵とする新規有機合成戦略の確立
2009 - 2011
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シリカゲルが引き起こすConia-ene型環化反応による新規複素環合成法の創出
2009 - 2010
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Conia-ene型反応を鍵段階とする創薬リード生物活性天然物の革新的合成戦略
2010 -
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グルタミン酸受容体作用性天然アミノ酸の合成研究
2007 - 2009
Education (4):
- - 2003 Nagasaki University
- - 2003 Nagasaki University Graduate School, Division of Pharmaceutical Sciences
- - 2001 Nagasaki University School of Pharmaceutical Sciences
- - 2001 Nagasaki University Faculty of Pharmaceutical Science
Professional career (1):
Association Membership(s) (2):
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