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J-GLOBAL ID:200901069932394942   Update date: Jan. 31, 2024

Takahashi Keisuke

タカハシ ケイスケ | Takahashi Keisuke
Affiliation and department:
Job title: Associate Professor
Homepage URL  (1): https://www.toho-u.ac.jp/phar/index.html
Research field  (1): Pharmaceuticals - chemistry and drug development
Research keywords  (2): 有機化学 ,  Organic chemstry
Research theme for competitive and other funds  (14):
  • 2018 - 2021 Synthetic studies of alkaloids possessing iNOS inducing activities
  • 2016 - 2019 Improvement of medaka embryo toxicity assay by a novel pulsed power electroporation system
  • 2015 - 2018 Development of new palladium catalyzed reactions utilizing the characteristic property of the ligand : switching of reaction pathway
  • 2013 - 2016 Synthetic Study of Tirandamycins
  • 2013 - 2016 Efficient Synthesis of Natural Products Useful for Drug Discovery Based on Innovative Synthetic Methodologies
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Papers (45):
  • Keisuke Takahashi, Shunya Kudo, Kiharu Kawamura, Taichi Kusakabe, Shoko Kikkawa, Isao Azumaya, Keisuke Kato. Synthesis of the Proposed Structure of Mohangic Acid C. Organic Letters. 2022. 24. 18. 3416-3420
  • Taichi Kusakabe, Dongwei Liu, Kaori Tsuchida, Shun Okazaki, Tsuyoshi Hashimoto, Akane Mori, Kentaro Yoshiwaka, Hiroaki Sasai, Keisuke Takahashi, Keisuke Kato. Reinvestigation of Methoxy-methoxycarbonylation of Monosubstituted Allenes. ChemistrySelect. 2022. 7. 13
  • Anri Hirai, Shouta Sugio, Collins Nimako, Shouta M. M. Nakayama, Keisuke Kato, Keisuke Takahashi, Koji Arizono, Tetsushi Hirano, Nobuhiko Hoshi, Kazutoshi Fujioka, et al. Ca2+ imaging with two-photon microscopy to detect the disruption of brain function in mice administered neonicotinoid insecticides. Scientific Reports. 2022. 12. 1
  • Collins Nimako, Yoshinori Ikenaka, Osei Akoto, Kazutoshi Fujioka, Kumiko Taira, Koji Arizono, Keisuke Kato, Keisuke Takahashi, Shouta M.M. Nakayama, Takahiro Ichise, et al. Simultaneous quantification of imidacloprid and its metabolites in tissues of mice upon chronic low-dose administration of imidacloprid. Journal of Chromatography A. 2021. 1652. 462350-462350
  • Kraisiri Khidkhan, Yoshinori Ikenaka, Takahiro Ichise, Shouta M.M. Nakayama, Hazuki Mizukawa, Kei Nomiyama, Hisato Iwata, Koji Arizono, Keisuke Takahashi, Keisuke Kato, et al. Interspecies differences in cytochrome P450-mediated metabolism of neonicotinoids among cats, dogs, rats, and humans. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology. 2021. 239. 108898-108898
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MISC (54):
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Books (1):
  • 天然物合成で活躍した反応 実験のコツとポイント
    化学同人 2011
Lectures and oral presentations  (5):
  • グルタミン酸受容体作用性天然物の合成研究
    (有機合成化学総合講演会 ( 2011)
  • エングレリン A の全合成
    (第37回反応と合成の進歩シンポジウム 2011)
  • C-Hアミノ化を基盤とするカイトセファリンの全合成研究
    (第53回天然有機化合物討論会 2011)
  • kaitocephalinの合成研究
    (日本薬学会第130年会 2010)
  • カイトセファリンの全合成
    (日本薬学会第132年会 2010)
Works (5):
  • C-Hアミノ化反応を活用するグルタミン酸受容体アンタゴニスト活性天然物の合成研究
    2011 - 2013
  • Conia-ene型環化を鍵とする新規有機合成戦略の確立
    2009 - 2011
  • シリカゲルが引き起こすConia-ene型環化反応による新規複素環合成法の創出
    2009 - 2010
  • Conia-ene型反応を鍵段階とする創薬リード生物活性天然物の革新的合成戦略
    2010 -
  • グルタミン酸受容体作用性天然アミノ酸の合成研究
    2007 - 2009
Education (4):
  • - 2003 Nagasaki University
  • - 2003 Nagasaki University Graduate School, Division of Pharmaceutical Sciences
  • - 2001 Nagasaki University School of Pharmaceutical Sciences
  • - 2001 Nagasaki University Faculty of Pharmaceutical Science
Professional career (1):
  • 博士(薬学) (長崎大学)
Association Membership(s) (2):
日本薬学会 ,  有機合成化学協会
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