Saito Maki

サイトウマキ | Saito Maki

Affiliation and department：
Job title：准教授

Research field (3)： Nutrition and health science , Pharmacology , Home economics, lifestyle science

Research keywords (7)：薬理学 , メカニカルストレス , Pulmonary arterial hypertension , 血管平滑筋 , メカノトランスダクション , vascular smooth muscle , mechanotransduction

Research theme for competitive and other funds (9)：

2019 - 2022 ファイトケミカルを含むインドール類縁体による難治性肺高血圧症病態制御の可能性
2017 - 2020 内因性および外因性因子によるメタボリックシンドロームの抑制性制御機構の解明
2015 - 2018 Prospects of inflammation resolving potential of n-3 polyunsaturated fatty acids for improvement of the prognosis in a rat model of pulmonary hypertension.
2012 - 2015 Study on the effects of n-3 polyunsaturated fatty acid on the medication for pulmonary hypertension with the experimental animal model.
2010 - 2012 The role of stretch signal induced by the adipocytes hypertrophy and activation of Rho/Rho kinase pathway in the pathogenesis of obesity

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Papers (46)：

Nanae Ishida, Maki Saito, Sachiko Sato, Yu Tezuka, Atsushi Sanbe, Eiichi Taira, Masamichi Hirose. Mizagliflozin, a selective SGLT1 inhibitor, improves vascular cognitive impairment in a mouse model of small vessel disease. Pharmacology Research & Perspectives. 2021. 9. 5
Yohei Sawa, Naoko Matsushita, Sachiko Sato, Nanae Ishida, Maki Saito, Atsushi Sanbe, Yoshihiro Morino, Eiichi Taira, Mami Obara, Masamichi Hirose. Chronic HDAC6 Activation Induces Atrial Fibrillation Through Atrial Electrical and Structural Remodeling in Transgenic Mice. International heart journal. 2021. 62. 3. 616-626
Tsuyoshi Chiba, Etsuko Kobayashi, Takashi Okura, Masashi Sekimoto, Hideya Mizuno, Maki Saito, Keizo Umegaki. An educational intervention improved knowledge of dietary supplements in college students. BMC public health. 2020. 20. 1. 633-633
Nanae Ishida, Maki Saito, Sachiko Sato, Hermann Koepsell, Eiichi Taira, Masamichi Hirose. SGLT1 participates in the development of vascular cognitive impairment in a mouse model of small vessel disease. Neuroscience letters. 2020. 727. 134929-134929
Maki Saito, Nanae Ishida, Hidetoshi Yamada, Miho Ibi, Masamichi Hirose. 8-HEPE-Concentrated Materials from Pacific Krill Improve Plasma Cholesterol Levels and Hepatic Steatosis in High Cholesterol Diet-Fed Low-Density Lipoprotein (LDL) Receptor-Deficient Mice. Biological & pharmaceutical bulletin. 2020. 43. 6. 919-924

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MISC (98)：

Effects of mizagliflozin, a selective SGLT1 inhibitor, on chronic hypoperfusion-induced vascular cognitive impairment. 2022. 253
Saito Maki. Effects of 3,3‘-diindolylmethane, a phytochemical in Brassica vegetables, on the activation of cardiac fibroblasts. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2022. 96. 1-B-P-083
向井諒一朗, 木暮恵吾, 高橋太志, 斉藤麻希, 石田菜々絵, 弘瀬雅教. アデニン誘発慢性腎臓病モデルマウス作製法の改良. 日本薬学会東北支部大会講演要旨集. 2019. 58th
斉藤麻希, 田辺由幸, 中山貢一, 弘瀬雅教. モノクロタリン肺高血圧ラット右心室における組織リモデリング関連因子の発現変動とオルメサルタンの効果. 日本薬学会年会要旨集(CD-ROM). 2019. 139th. ROMBUNNO.22PO-pm192
石田菜々絵, 斉藤麻希, 衣斐美歩, KOEPSELL Hermann, 平英一, 弘瀬雅教. SGLT1は,脳血管障害性認知症の発症に関与する。. Anti-Aging Science. 2018. 10. 1. 63

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Patents (1)：

糖尿病白内障の治療剤

Books (1)：

薬系薬理学書 = Pharmacology for pharmacy
南江堂 2018 ISBN:9784524403295

Lectures and oral presentations (5)：

肺高血圧症を発症したラットへのオルメサルタン投与が生命予後に与える影響
(日本薬理学会北部会プログラム・抄録集 2017)
モノクロタリン肺高血圧ラット肺組織における炎症性サイトカインの発現に対するオルメサルタンの効果
(日本薬理学会北部会プログラム・抄録集 2014)
モノクロタリン誘発肺高血圧ラットへのオルメサルタン長期投与の効果
(次世代を担う創薬・医療薬理シンポジウムプログラム・要旨集 2014)
モノクロタリン誘発肺高血圧ラット肺動脈にみられる伸展誘発性律動的収縮反応への分泌型ホスホリパーゼA<sub>2</sub>の関与
(Pharmaco-Hematologyシンポジウム講演要旨集 2013)
ラット網膜循環調節におけるシクロオキシゲナーゼの役割
(岩手医学雑誌 2009)

Professional career (2)：

Master(Pharmaceutical Sciences) (University of Shizuoka)
Doctor(Pharmaceutical Sciences) (University of Shizuoka)

Association Membership(s) (5)：

Japanese Pulmonary Circulation and Pulmonary Hypertension Society , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE PHARMACOLOGICAL SOCIETY , 日本血管生物医学会 , THE PHARMACEUTICAL SOCIETY OF JAPAN

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