Rchr
J-GLOBAL ID:200901075681782280
Update date: Nov. 12, 2024
YOKOYAMA Miki
YOKOYAMA Miki
Contact this researcher
You can send email directly to the researcher.
Affiliation and department:
Institute of Science Tokyo Graduate School of Medical and Dental Sciences
About Institute of Science Tokyo Graduate School of Medical and Dental Sciences
Search "Institute of Science Tokyo Graduate School of Medical and Dental Sciences"
Job title:
Lecturer
Research field (3):
Oral medicine
, Immunology
, Structural biochemistry
Research keywords (7):
LAMP-2
, LAMP-1
, スフィンゴ脂質
, CD38
, 構造生物化学
, Immunology
, Structural Biochemistry
Research theme for competitive and other funds (13):
2017 - 2020 LAMP-2のアセンブリ制御を利用した塗布式口腔ケアによる癌治療患者のQOL改善
2013 - 2017 LAMP2を標的としたリソソーム細胞内輸送のブロッキングによる顎骨吸収の抑制
2010 - 2012 ネクロプトーシスによる細胞死におけるスフィンゴ脂質代謝の役割
2005 - 2006 Fab-ブリッジを用いたB細胞受容体架橋刺激の分子機構解析
2002 - 2005 Immunoregulation by CD38
1998 - 2003 Lipid microdomains in secretory granules of rat parotid acinar cells
1995 - 2003 Effects of gangliosides on the ecto-NADase activities
1999 - 2000 耳下腺腺房細胞分泌顆粒におけるコレステロール・糖脂質マイクロドメイン
1998 - 1999 糖脂質による細胞表層シグナル伝達タンパク質の配向の制御
1997 - 1998 耳下腺腺房細胞におけるチモーゲン顆粒の生成機構
1991 - 百日咳毒素ADPリボシル化活性に対する内在性阻害物質の細胞内での標的分子の同定
1988 - 1990 内在的ADPリボシル化反応によるGTP結合タンパク質の機能制御
1987 - すい臓の外分泌過程に関与するGTP結合タンパク質の役割り
Show all
Papers (40):
Yuji Kato, Satoko Arakawa, Kazue Terasawa, Jin-Ichi Inokuchi, Takanori Iwata, Shigeomi Shimizu, Tetsuro Watabe, Miki Hara-Yokoyama. The ceramide analogue N-(1-hydroxy-3-morpholino-1-phenylpropan-2-yl)decanamide induces large lipid droplet accumulation and highlights the effect of LAMP-2 deficiency on lipid droplet degradation. Bioorganic & medicinal chemistry letters. 2020. 30. 3. 126891-126891
Hara-Yokoyama M, Kurihara H, Ichinose S, Matsuda H, Ichinose S, Kurosawa M, Tada N, Iwahara C, Terasawa K, Podyma-Inoue KA, et al. KIF11 as a Potential Marker of Spermatogenesis Within Mouse Seminiferous Tubule Cross-sections. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 2019. 67. 11. 813-824
Yamamoto D, Kayamori K, Sakamoto K, Tsuchiya M, Ikeda T, Harada H, Yoda T, Watabe T, Hara-Yokoyama M. Intracellular claudin-1 at the invasive front of tongue squamous cell carcinoma is associated with lymph node metastasis. Cancer science. 2019. 111. 2. 700-712
Jin-Ichi Inokuchi, Takashi Ode, Miki Hara-Yokoyama. Pharmacological Modulation of Glycosphingolipid Metabolism. Methods in molecular biology (Clifton, N.J.). 2018. 1804. 401-410
Takashi Ode, Katarzyna A. Podyma-Inoue, Kazue Terasawa, Jin-ichi Inokuchi, Toshihide Kobayashi, Tetsuro Watabe, Yuichi Izumi, Miki Hara-Yokoyama. PDMP, a ceramide analogue, acts as an inhibitor of mTORC1 by inducing its translocation from lysosome to endoplasmic reticulum. EXPERIMENTAL CELL RESEARCH. 2017. 350. 1. 103-114
more...
MISC (20):
エクトNAD分解酵素の細胞表面阻害物質としてのガングリオシド. 生化学. 2001. 40. 4. 888-895
M Kukimoto, O Nureki, M Shirouzu, T Katada, Y Hirabayashi, H Sugiya, S Furuyama, S Yokoyama, M Hara-Yokoyama. Crystallization and preliminary X-ray diffraction analysis of the extracellular domain of the cell surface antigen CD38 complexed with ganglioside. JOURNAL OF BIOCHEMISTRY. 2000. 127. 2. 181-184
Junko Fujita-Yoshigaki, Yoko Dohke, Miki Hara-Yokoyama, Shunsuke Furuyama, Hiroshi Sugiya. Presence of a complex containing vesicle-associated membrane protein 2 in rat parotid acinar cells and its disassembly upon activation of cAMP- dependent protein kinase. Journal of Biological Chemistry. 1999. 274. 33. 23642-23646
H Michikawa, Y Mitsui, J Fujita-Yoshigaki, M Hara-Yokoyama, S Furuyama, H Sugiya. cGMP production is coupled to Ca2+-dependent nitric oxide generation in rabbit parotid acinar cells. CELL CALCIUM. 1998. 23. 6. 405-412
Translocation of Arfl to the Secretory Granules in Rat Parotid Acinar Cells. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 1998. 357. 1. 147-154
more...
Books (1):
PERTUSSIS TOXIN CATALYZED ADP-RIBOSYLATION OF G-RPOTEINS IS INHIBITED BY AN ENDOGENOUS INHIBITOR IN BOVINE BRAIN
Elsevier 1989
Education (4):
- 1986 東京大学大学院 理学系研究科 生物化学
- 1986 The University of Tokyo Graduate School, Division of Science Biochemistry and biophysics
- 1981 The University of Tokyo Faculty of Science
- 1981 The University of Tokyo Faculty of Science Biochemistry and biophysics
Professional career (1):
PhD (The University of Tokyo)
Work history (7):
2004 - 現在 Tokyo Medical and Dental University
1997 - 2001 Nihon University School of Dentistry at Matsudo
1997 - 2001 Nihon University School of Dentistry at Matsudo, Lecturer
2001 - - 東京医科歯科大学 講師
2001 - - Tokyo Medical and Dental University, Lecturer
1986 - 1997 Nihon University School of Dentistry at Matsudo
1986 - 1997 Nihon University School of Dentistry at Matsudo, Research Assistant
Show all
Committee career (1):
1999 - FCCA 幹事
Association Membership(s) (6):
免疫学会
, 日本脂質生化学会
, FCCA
, 歯科基礎医学会
, 日本糖質学会
, 日本生化学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in
researchmap
.
For details, see here
.
Return to Previous Page
TOP
BOTTOM