Rchr
J-GLOBAL ID:200901076229508967
Update date: Jan. 30, 2024
Suzuki Toshihiro
スズキ トシヒロ | Suzuki Toshihiro
Affiliation and department:
Homepage URL (1):
http://www.my-pharm.ac.jp/~tssuzuki/home/index.html
Research field (1):
Tumor biology
Research keywords (9):
3次元培養
, ハイスループット薬物評価系
, 耐性克服剤の開発
, マイクロアレイ
, 肺癌
, Cisplatin
, EGFR-TKI耐性
, MDR
, Multi Drug Resistance Protein
Research theme for competitive and other funds (10):
- 2015 - 2018 Prediction of the phosphorylation signal response of receptor-type tyrosine kinase (RTK) inhibitors using miRNA as a biomarker.
- 2012 - 2015 Prediction of sorafenib response by FGF3 gene amplification for patients with hepatocellular carcinoma
- 2012 - 2015 Uptake mechanisms study and molecular analysis of biomedicine in tissue culture system.
- 2010 - 2011 Construction of the miRNA database associate with chemotherapeutic sensitivity in lung cancer.
- 2008 - 2009 Functional analysis of miRNA dependent cisplatin resistance mechanisms.
- 2006 - 2008 Structure-based modification of lysosomal enzymes: development of new enzyme replacement therapy for lysosomal diseases
- MRP5の発現と機能に関する研究
- 重金属解毒における多剤耐性タンパク質の役割
- Function and Expression Analysis of MRP5
- Function of Multi Drug Resistance Protein on Detoxification of Heavy Metals.
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Papers (75):
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Toshihiro Suzuki, Nachanun Sirimangkalakitti, Asami Baba, Ryoko Toyoshima-Nagasaki, Yuna Enomoto, Naoki Saito, Yuki Ogasawara. Characterization of the nucleotide excision repair pathway and evaluation of compounds for overcoming the cisplatin resistance of non-small cell lung cancer cell lines. Oncology Reports. 2022. 47. 4
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Ko Sugiura, Shin Koike, Toshihiro Suzuki, Yuki Ogasawara. Carbonylation of skin collagen induced by reaction with methylglyoxal. Biochemical and biophysical research communications. 2021. 562. 100-104
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Shin Koike, Yusuke Miyaji, Hinako Sano, Natsuki Aikawa, Masayuki Kai, Sakura Kasahara, Toshihiro Suzuki, Shoichi Nishimoto-Kusunose, Yuki Ogasawara. Simultaneous determination of five bile acids as potential biomarkers for Alzheimer's disease in mouse brain and plasma. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2021. 37. 8. 1165-1170
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Ko Sugiura, Shin Koike, Toshihiro Suzuki, Yuki Ogasawara. Oxidative Formation of Methylglyoxal in Glycerol Preparations during Storage. Biological & pharmaceutical bulletin. 2020. 43. 5. 879-883
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Shin Koike, Chihiro Ando, Yosuke Usui, Yosuke Kibune, Shoichi Nishimoto, Toshihiro Suzuki, Yuki Ogasawara. Age-related alteration in the distribution of methylglyoxal and its metabolic enzymes in the mouse brain. Brain research bulletin. 2019. 144. 164-170
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MISC (78):
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馬場麻実, 西尾和人, 鈴木俊宏. ヌクレオチド除去修復を介したレニエラマイシン類によるシスプラチン耐性の克服. 日本がん分子標的治療学会学術集会プログラム・抄録集. 2019. 23rd
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伊東 里紗, 鈴木 俊宏, 山岡 利光, 大森 亨, 西尾 和人, 小笠原 裕樹. 3次元培養法を用いたキナーゼ阻害剤の感受性評価(Evolution of kinase inhibitors sensitivity in three-dimensional suspended spheroid culture platform). 日本癌学会総会記事. 2018. 77回. 1703-1703
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木船 陽介, 鹿山 将, 小池 伸, 鈴木 俊宏, 石田 洋一, 堀内 泰江, 宮下 光弘, 新井 誠, 小笠原 裕樹. 統合失調症患者赤血球中のアルグピリミジン化タンパク質の同定. 日本薬学会年会要旨集. 2018. 138年会. 3. 133-133
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木船 陽介, 鹿山 将, 小池 伸, 鈴木 俊宏, 石田 洋一, 堀内 泰江, 宮下 光弘, 新井 誠, 小笠原 裕樹. 統合失調症患者赤血球中のアルグピリミジン化タンパク質の同定. 日本薬学会年会要旨集. 2018. 138年会. 3. 133-133
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伊東里紗, 山岡利光, 大森亨, 西尾和人, 鈴木俊宏. 3次元培養法による薬剤耐性細胞株の評価. 日本がん分子標的治療学会学術集会プログラム・抄録集. 2018. 22nd
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Works (4):
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新規プラチナ化合物のチオール結合性と耐性克服作用の解析
2001 -
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Study of Drug Resistance and its Circumvention on Novel Platinum Compounds.
2001 -
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癌化学療法における薬剤耐性機構の解明
2000 -
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Study of Drug Resistance Mechanisms on Cancer Chemotherapy
2000 -
Education (4):
- - 1999 Meiji Pharmaceutical University
- - 1999 Meiji Pharmaceutical University Graduate School, Division of Pharmaceutical Sciences
- - 1994 Meiji Pharmaceutical University Faculty of Pharmacy
- - 1994 Meiji Pharmaceutical University Faculty of Pharmaceutical Science
Professional career (1):
- Ph. D (Meiji Pharmaceutical University)
Association Membership(s) (4):
日本薬学会
, 日本癌学会
, 日本生化学会
, 日本がん分子標的治療学会
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