Research field (5)：
Applied biochemistry
, Genomics
, Functional biochemistry
, Structural biochemistry
, Molecular biology
Research keywords (5)：
DNA
, Gene
, Protein
, セントラルドグマ
, CRISPR-Cas
Research theme for competitive and other funds (3)：
2016 - 2020 高分解能な立体構造解析による、高度好熱菌獲得免疫システムの解明
2013 - 2016 1つの細胞が持つ新奇なウイルス防御システムの体系的理解
2010 - 2013 mRNA発現解析に基づいた、機能未知遺伝子の分類
Papers (79)：
Akeo Shinkai, Hideharu Hashimoto, Chikako Shimura, Hiroaki Fujimoto, Kei Fukuda, Naoki Horikoshi, Masaki Okano, Hitoshi Niwa, Erik W Debler, Hitoshi Kurumizaka, et al. The C-terminal 4CXXC-type zinc finger domain of CDCA7 recognizes hemimethylated DNA and modulates activities of chromatin remodeling enzyme HELLS. NUCLEIC ACIDS RESEARCH. 2024. 52. 17. 10194-10219
Jurre A Steens, Yifan Zhu, David W Taylor, Jack P K Bravo, Stijn H P Prinsen, Cor D Schoen, Bart J F Keijser, Michel Ossendrijver, L Marije Hofstra, Stan J J Brouns, et al. SCOPE enables type III CRISPR-Cas diagnostics using flexible targeting and stringent CARF ribonuclease activation. NATURE COMMUNICATIONS. 2021. 12. 1. 5033
The C-terminal 4CXXC-type zinc finger domain of CDCA7 recognizes hemimethylated DNA and modulates activities of chromatin remodeling enzyme HELLS
(FASEB Science Research Conference, Biological Methylation: Fundamental Mechanisms 2024)
