Rchr
J-GLOBAL ID：200901078527681011   Update date: Sep. 18, 2024

Masutani Mitsuko

マスタニ ミツコ | Masutani Mitsuko
Affiliation and department：
Nagasaki University Graduate School of Biomedical Sciences

About Nagasaki University Graduate School of Biomedical Sciences


Job title： Chief
Other affiliations (1)：
  • National Cancer Center Research Institute  Specially Appointed Chief
Research field  (6)： Pathobiochemistry ,  Pharmacology ,  Pharmaceuticals - health and biochemistry ,  Cell biology ,  Molecular biology ,  Biochemistry
Research keywords  (16)： molecular medicine ,  drug development ,  radiation biology ,  BNCT (boron neutron capture therapy) ,  がん治療 ,  がん予防 ,  生化学 ,  発がん ,  DNA損傷応答 ,  翻訳後修飾 ,  ポリ(ADP-リボース) ,  Carcinogenesis ,  Biochemistry ,  DNA damage response ,  ADP-ribose ,  Poly(ADP-ribose)
Research theme for competitive and other funds  (26)：
  • 2024 - 2027 Inhibitors of kynurenine production: drug development of non-conventional IDO1 inhibitor A and elucidation of mechanism of action by cpd B.
  • 2018 - 2022 BNCTにおける治療局所・全身性応答と治療奏効性、副作用のバイオマーカーの同定
  • 2016 - 2019 Development of DNA damaging agents using poly(ADP-ribose) hydrolysates
  • 2015 - 2018 Study on characteristics of small RNA secreted from the pluripotent stem cells
  • 2015 - 2018 A comprehensive genome-wide screen of radiosensitization targets
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Papers (124)：
  • Satoshi Nakamura, Mihiro Takemori, Tetsu Nakaichi, Yasunori Shuto, Tairo Kashihara, Kotaro Iijima, Takahito Chiba, Hiroki Nakayama, Yuka Urago, Shuka Nishina, et al. A method for delivering the required neutron fluence in an accelerator-based boron neutron capture therapy system employing a lithium target. Scientific reports. 2024. 14. 1. 11253-11253
  • Yuka Sasaki, Takuma Inouchi, Ryusuke Nakatsuka, Amane Inoue, Mitsuko Masutani, Tadashige Nozaki. Activated NAD+ biosynthesis pathway induces olaparib resistance in BRCA1 knockout pancreatic cancer cells. PLOS ONE. 2024
  • Keitaro Nakamoto, Sota Kikuhara, Hiroaki Fujimori, Barkha Saraswat, Zhongming Gao, Ankitha Vadi Velu, Zongxiang Zhang, Tong Ying, Shoji Imamichi, Tadashige Nozaki, et al. Effect of Functional Inhibition of BACE1 on Sensitization to γ-Irradiation in Cancer Cells. Current Issues in Molecular Biology. 2024
  • Yuka Sasaki, Ryusuke Nakatsuka, Amane Inoue, Takuma Inouchi, Mitsuko Masutani, Tadashige Nozaki. Dysfunction of poly (ADP-ribose) glycohydrolase suppresses osteoclast differentiation in RANKL-stimulated RAW264 cells. Biochemical and biophysical research communications. 2023. 692. 149309-149309
  • Tong Ying, Gao Zhongming, Imamichi Shoji, Sanada Yu, 佐々木 由香, 野崎 中成, Suzuki Minoru, Masunaga Shinichiro, 益谷 美都子. BNCT後の早期反応バイオマーカーとしてのHMGB1の動的プロファイル(Dynamic profile of HMGB1 as a biomarker for the early response after BNCT). 日本癌学会総会記事. 2023. 82回. 2156-2156
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MISC (432)：
  • ZHANG Zongxiang, 中本恵太郎, SARASWAT Barkha, GAO Zhongming, VELU Ankitha Vadi, TONG Ying, MASUTANI Mitsuko. Radiosensitization effect of BACEI after γ-irradiation in cancer cells. 日本薬学会年会要旨集(Web). 2024. 144th
  • 益谷 美都子, 木村 雄亮, 池内 真志. 新型コロナウィルス感染早期診断用ポータブルデバイスの実用化検証. 生体医歯工学共同研究拠点成果報告書. 2023. 2022年度. 110-110
  • BARKHA Saraswat, VADI Velu Ankitha, GAO Zhomgming, TONG Ying, FUJIMORI Hiroaki, FUJIMORI Hiroaki, HIRAI Takahisa, MASUTANI Mitsuko. Radiosensitization effects and mechanism of PARP inhibitors on cancer cells. 日本生化学会大会(Web). 2023. 96th
  • 村山広樹, TONG Ying, SARASWAT Barkha, 林康平, 林康平, 林康平, 益谷美都子. Development of evaluation model of flow cytometry for combination effects of anti-cancer agents using machine learning. 日本分子生物学会年会プログラム・要旨集(Web). 2023. 46th
  • VELU Ankitha Vadi, SARASWAT Barkha, TONG Ying, MYAT Aung Bhone, MATSUNO Kenji, TAKAMURA Takeji, KOIZUMI Fumiaki, MASUTANI Mitsuko. Cell death responses induced by a potential anti-cancer agent MO2455 in lymphoma U937 cells. 日本薬学会年会要旨集(Web). 2023. 143rd
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Patents (7)：
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Books (10)：
  • PARP inhibitors for Cancer Therapy.
    Springer International 2015
  • Polymerization
    In Tech 2012
  • DNA repair and human cancers : Extended abstracts for the 40th International Symposium of the Princess Takamatsu Cancer Research Fund : November 10-12, 2009 Tokyo, Japan
    Princess Takamatsu Cancer Research Fund 2010
  • New Developments in Stem Cell Research
    Nova Science Publishers, Inc. 2006
  • Poly(ADP-Ribosyl)ation
    Eurekah.com. 2004
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Education (6)：
  • Okayama University Faculty of Pharmaceutical Sciences Department of Pharmacy
  • Okayama University
  • The University of Tokyo
  • Okayama University Faculty of Pharmaceutical Science
  • Okayama University Graduate School, Division of Pharmaceutical Sciences
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Professional career (1)：
  • Ph.D. (The University of Tokyo)
Work history (11)：
  • 2019/10 - 現在 Nagasaki University Department of Molecular and Genomic Biomedicine, Center for Bioinformatics and Molecular Medicine, Graduate School of Biomedical Sciences Professor
  • 2015/02 - 2019/09 Nagasaki University Department of Frontier Life Sciences, Graduate School of Biomedical Sciences Professor
  • 2014/07 - 2015/01 National Cancer Center Division of Chemotherapy and Clinical Cancer Research
  • 2010 - 2014 National Cancer Center Division of Genome Stability Research
  • 2007/07 - 2010/11 National Cancer Center Research Institute Biochemistry Division Chief
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Awards (1)：
  • 2000 - 田宮賞
Association Membership(s) (9)：
Japanese Society of Neutron Capture Therapy(JSNCT) ,  The Japanese Society for Regenerative Medicine ,  Japanese Association for Molecular Target Therapy of Cancer ,  分子病理学研究会 ,  The Pharmaceutical Society of Japan ,  American Association for Cancer Research ,  日本分子生物学会 ,  日本生化学会 ,  日本癌学会
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