Rchr
J-GLOBAL ID：200901079785967759
Update date: May. 27, 2024
Watanabe Takaaki
Watanabe Takaaki
Affiliation and department：
Research field (4)：
Tumor biology
, Medical biochemistry
, Cell biology
, Molecular biology
Research keywords (12)：
UV
, DNA damage response
, PLA
, TC-NER
, DGCR8
, R-loop
, non-cording RNA
, Oncogene
, Replication restart
, Replication stalling
, DNA replication
, Gene amplification
Research theme for competitive and other funds (2)：
- 2021 - 2026 The novel roles of microRNA biogenesis factors in DNA repair
- 2017 - 2019 Regulation of the Fanconi anemia-BRCA pathway
Papers (15)：
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Ryusuke Suzuki, Michael M Murata, Nicholas Manguso, Takaaki Watanabe, Lila Mouakkad-Montoya, Fumie Igari, Md Maminur Rahman, Ying Qu, Xiaojiang Cui, Armando E Giuliano, et al. The fragility of a structurally diverse duplication block triggers recurrent genomic amplification. Nucleic Acids Research. 2021. 49. 1. 244-256
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Hisashi Tanaka, Takaaki Watanabe. Mechanisms Underlying Recurrent Genomic Amplification in Human Cancers. Trends in cancer. 2020. 6. 6. 462-477
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Watanabe T, Tanaka H, Horiuchi T. Complex repeat structure promotes hyper-amplification and amplicon evolution through rolling-circle replication. Nucleic acids research. 2018. 46. 10. 5097-5108
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Takaaki Watanabe, Michael Marotta, Ryusuke Suzuki, Scott J. Diede, Stephen J. Tapscott, Atsushi Niida, Xiongfong Chen, Lila Mouakkad, Anna Kondratova, Armando E. Giuliano, et al. Impediment of Replication Forks by Long Non-coding RNA Provokes Chromosomal Rearrangements by Error-Prone Restart. CELL REPORTS. 2017. 21. 8. 2223-2235
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Michael Marotta, Taku Onodera, Jeffrey Johnson, G. Thomas Budd, Takaaki Watanabe, Xiaojiang Cui, Armando E. Giuliano, Atsushi Niida, Hisashi Tanaka. Palindromic amplification of the ERBB2 oncogene in primary HER2-positive breast tumors. SCIENTIFIC REPORTS. 2017. 7. 41921
ｍore...
MISC (8)：
Lectures and oral presentations (13)：
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癌細胞のゲノム可塑性に関わるDNA複製阻害と長鎖ノンコーディングRNA転写
(日本分子生物学会年会プログラム・要旨集(Web) 2014)
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ダブルローリングサークル複製を中心とする包括的な遺伝子増幅モデル
(日本遺伝学会大会プログラム・予稿集 2011)
-
環状染色体(原核生物)から線状染色体(真核生物)への変化
(日本遺伝学会大会プログラム・予稿集 2011)
-
ダブルローリングサークル複製(DRCR)を起こすゲノムは他にあるか?(Are there any genomes that duplicate through double rolling circle replication (DRCR)?)
(日本生化学会大会・日本分子生物学会年会合同大会講演要旨集 2010)
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ダブルローリングサークル複製を中心とする包括的な遺伝子増幅モデル(A comprehensive model of gene amplification centering on double rolling-circle replication (DRCR))
(日本生化学会大会・日本分子生物学会年会合同大会講演要旨集 2010)
ｍore...
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