Iwamoto Ryo

イワモトリョウ | Iwamoto Ryo

Affiliation and department：
Job title： Associate Professor

Research field (1)： Cell biology

Research keywords (4)： Cell Biology , 細胞間情報伝達 , 増殖因子 , 細胞生物学

Research theme for competitive and other funds (55)：

2018 - 2022 Inhibition of cell proliferation by induction of HB-EGF-HSPG-ErbB4 signaling system
2014 - 2017 Development of a novel anti-cancer therapeutics targeting HB-EGF
2015 - 2017 HB-EGF-ErbB4シグナルによる細胞増殖制御機構とその応用
2012 - 2014 ADAM17によるHB-EGFのエクトドメイン・シェディングに関与する制御機構
2008 - 2010 Regulation of cell proliferation by HB-EGF in mouse cardiac valve development

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Papers (114)：

Shuhao Lin, Daiki Hirayama, Gembu Maryu, Kimiya Matsuda, Naoya Hino, Eriko Deguchi, Kazuhiro Aoki, Ryo Iwamoto, Kenta Terai, Michiyuki Matsuda. Redundant roles of EGFR ligands in the ERK activation waves during collective cell migration. Life science alliance. 2022. 5. 1
Masaki Yamato, Takashi Matsuzaki, Ryo Araki, Shota Tsuchida, Keiji Okuda, Hai Ying Fu, Shoji Sanada, Hiroshi Asanuma, Yoshihiro Asano, Masanori Asakura, et al. RNA Aptamer Binds Heparin-Binding Epidermal Growth Factor-Like Growth Factor with High Affinity and Specificity and Neutralizes Its Activity. International Journal of Gerontology. 2017. 11. 3. 191-196
Ryo Iwamoto, Naoki Mine, Hiroto Mizushima, Eisuke Mekada. ErbB1 and ErbB4 generate opposing signals regulating mesenchymal cell proliferation during valvulogenesis. Journal of Cell Science. 2017. 130. 7. 1321-1332
Shingo Miyamoto, Fusanori Yotsumoto, Taeko Ueda, Tatsuya Fukami, Ayako Sanui, Kohei Miyata, Sung Ouk Nam, Satoshi Fukagawa, Takahiro Katsuta, Miyako Maehara, et al. BK-UM in patients with recurrent ovarian cancer or peritoneal cancer: A first-in-human phase-I study. BMC Cancer. 2017. 17. 1. 89
Takashi Suzuki, Keiko Itano, Rong Zou, Ryo Iwamoto, Eisuke Mekada. Mathematical Modeling for Break Down of Dynamical Equilibrium in Bone Metabolism. ROLE AND IMPORTANCE OF MATHEMATICS IN INNOVATION. 2017. 25. 25-34

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MISC (65)：

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Patents (3)：

Books (4)：

Mathematical Modeling for Break Down of Dynamical Equilibrium in Bone Metabolism
Springer 2017 ISBN:9789811009624
Endocytosis and signal transduction.
1999
Diphtheria toxin
1996
Juxtacrine stimulation mediated by membrane-anchored growth factors.
1996

Lectures and oral presentations (17)：

マウス心臓弁形成過程におけるHB-EGF-ErbBシグナルによる細胞増殖制御
(第68回日本細胞生物学会大会 2016)
Physiological functions of diphtheria toxin receptor/HB-EGF
(17TH EUROPEAN WORKSHOP ON BACTERIAL PROTEIN TOXINS 2015)
Diphtheria toxin mutants with enhanced inhibitory activity against HB-EGF for cancer therapy
(17TH EUROPEAN WORKSHOP ON BACTERIAL PROTEIN TOXINS 2015)
破骨細胞分化過程におけるHB-EGF細胞質内領域の機能
(第66回日本細胞生物学会大会 2014)
心臓弁形成におけるHB-EGF-ErbBシグナルによる細胞増殖制御
(第66回日本細胞生物学会大会 2014)

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Education (4)：

Professional career (1)：

Work history (10)：

2000 - 2005 Research Institute for Microbial Diseases, Osaka University, Assistant Professor
2000 - 2005 Osaka University Research Institute for Microbial Diseases
2005 - - Research Institute for Microbial Diseases, Osaka University, Associate Professor
2005 - - 大阪大学微生物病研究所助教授
1989 - 2000 Institute of Life Science, Kurume University, Research Assistant

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Association Membership(s) (4)：

The American Society for Cell Biology , 日本分子生物学会 , 日本生化学会 , 日本細胞生物学会

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