Research field (4)：
Pharmaceuticals - chemistry and drug development
, Synthetic organic chemistry
, Bioorganic chemistry
, Structural/physical organic chemistry
Research theme for competitive and other funds (22)：
2023 - 2026 Creation of gigantic chemical space science: Establishment of scientific principles for finding useful compounds from hundreds of millions of unknown compounds
2020 - 2023 Strategic Molecular Design Aiming at Streamlined Chemical Transformations
2019 - 2021 Exploratory Study on TriQuinoline, A MInituarized Model of Graphene with Atomic-Sized Defect
2018 - 2020 Reaction Development Empowered by Peculiar B3NO2 Heterocycle
2017 - 2020 Development of Sustainable Chemical Reactions Driven by Designed Cooperative Catalysts
2016 - 2018 Development of Catalytic Asymmetric C–C Bond-Forming Reactions Using Alkylnitriles as Pronucleophiles
2014 - 2016 Strategic regulation of molecular ensembles via programmed hybridization of smart catalysts
2013 - 2016 Development of cooperative asymmetric catalysts and their applications to enantioselective synthesis of therapeutics
2013 - 2015 ニトリルのα-C-H活性化による不斉C-C結合形成反応の開拓
2012 - 2014 適時構造・機能変化型触媒系を用いる多段階促進型反応の開発
2011 - 2012 Development of direct catalytic asymmetric C-C bond-forming reactions based on thioamides and their applications to enantioselective synthesis of thtrapeutics
2008 - 2012 Innovative Asymmetris Synthesis of Pharmaceuticals Through Strategic Development of Multifunctional and Multimetallic Catalysts
2011 - 2011 Development of Multifunctional Catalyst Operated byπ-Complexation Toward the Efficient Production of Enantioenriched Tetrasubstitutedα-Amino Acids.
2008 - 2010 Advanced Control of Stereoselectivity and Chemoselectivity Through Supramolecular Chemistry
2008 - 2008 革新的動的多核触媒の創製と機構解明
2007 - 2008 Development of Catalytic Asymmetric Reactions for the Construction of Stereogenic Tetrasubstituted Carbon with 100% Atom-efficiency and Its Application to the Reactions with Allosteric Regulation
2003 - 2007 Innovational Asymmetric Catalysis縲廾ptimization and New Development
2002 - 2004 環境調和型触媒的不斉炭素-炭素結合形成反応の開発と実践的合成への展開
不斉触媒化学 医薬品合成
Organic Chemistry
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Papers (151)：
Toi Kobayashi, Naoya Kumagai. Oxa-TriQuinoline: A New Entry to Aza-Oxa-Crown Architectures. Angewandte Chemie (International ed. in English). 2023. e202307896
Ryosuke Tsutsumi, Nobuaki Kashiwagi, Naoya Kumagai. Expeditious Access to the B3NO2 Heterocycle Enabling Modular Derivatization. The Journal of organic chemistry. 2023. 88. 9. 6247-6251
Miki Kohei, Naoki Takizawa, Ryosuke Tsutsumi, Wei Xu, Naoya Kumagai. Azo-tagged C4N4 fluorophores: unusual overcrowded structures and their application to fluorescent imaging. Organic & biomolecular chemistry. 2023
Christopher R. Opie, Hidetoshi Noda, Masakatsu Shibasaki, Naoya Kumagai. Less Is More: N(BOH)2 Configuration Exhibits Higher Reactivity than the B3NO2 Heterocycle in Catalytic Dehydrative Amide Formation. Organic Letters. 2023. 25. 4. 694-697
Wei Xu, Yuuya Nagata, Naoya Kumagai. TEtraQuinolines: A Missing Link in the Family of Porphyrinoid Macrocycles. Journal of the American Chemical Society. 2023. 145. 4. 2609-2618
Jin Cui, Toshifumi Takeuchi, Akimichi Ohtsuki, Takumi Watanabe, Naoya Kumagai, Masakatsu Shibasaki. Direct Catalytic Asymmetric Aldol Reaction of α-Vinyl Thioamide and Amide and their Applications in Enantioselective Synthesis of Natural Products. 2018. 60. 0
Hidetoshi Noda, Makoto Furutachi, Yasuko Asada, Masakatsu Shibasaki, Naoya Kumagai. Unique Physicochemical and Catalytic Properties Dictated by the B3NO2 Ring System. SYNLETT. 2017. 28. 16. A165-A168
