Otsuki Noriko

オオツキノリコ | Otsuki Noriko

Affiliation and department：
Homepage URL (1)： https://doctor-trust.co.jp/

Research field (3)： Cell biology , Immunology , Molecular biology

Research keywords (4)： Neuromuscular disease , spinal muscular atrophy , BTLA , Costimulatory molecule

Papers (24)：

Noriko Otsuki, Tamaki Kato, Mamoru Yokomura, Mari Urano, Mari Matsuo, Emiko Kobayashi, Kazuhiro Haginoya, Hiroyuki Awano, Yasuhiro Takeshima, Toshio Saito, et al. Analysis of SMN protein in umbilical cord blood and postnatal peripheral blood of neonates with SMA: a rationale for prompt treatment initiation to prevent SMA development. Orphanet journal of rare diseases. 2025. 20. 1. 91-91
Makiko Mochizuki-Kashio, Noriko Otsuki, Kota Fujiki, Sherif Abdelhamd, Peter Kurre, Markus Grompe, Atsushi Iwama, Kayoko Saito, Ayako Nakamura-Ishizu. Replication stress increases mitochondrial metabolism and mitophagy in FANCD2 deficient fetal liver hematopoietic stem cells. Frontiers in Oncology. 2023. 13
Takano Kozue, Uchiyama Toshitaka, Otsuki Noriko, Nishio Hisahide, Kubo Yuji, Arakawa Reiko, Saito Toshio, Takeshima Yasuhiro, Yuge Kotaro, Ikeda Toshio, et al. Effective Valproic Acid Treatment in Motor Function Is Caused by Possible Mechanism of Elevated Survival Motor Neuron Protein Related With Splicing Factor Gene Expression in Spinal Muscular Atrophy. Tokyo Women's Medical University Journal. 2022. 6. 57-66
Otsuki N, Arakawa R, Kaneko K, Aoki R, Arakawa M, Saito K. A new biomarker candidate for spinal muscular atrophy: Identification of a peripheral blood cell population capable of monitoring the level of survival motor neuron protein. PloS one. 2018. 13. 8. e0201764
H. Akiyama, M. Nose, N. Ohtsuki, S. Hisaka, H. Takiguchi, A. Tada, N. Sugimoto, H. Fuchino, T. Inui, N. Kawano, et al. Evaluation of the safety and efficacy of Glycyrrhiza uralensis root extracts produced using artificial hydroponic and artificial hydroponic-field hybrid cultivation systems. JOURNAL OF NATURAL MEDICINES. 2017. 71. 1. 265-271

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MISC (11)：

大月典子, 加藤環, 横村守, 松尾真理, 齋藤加代子. 脊髄性筋萎縮症における治療有効性モニタリングのためのバイオマーカーの開発. 東京女子医科大学総合研究所紀要. 2022. 41
SAITO KAYOKO, ARAKAWA REIKO, KANEKO KAORU, OTSUKI NORIKO, KUBO YUJI, ARAKAWA MASAYUKI, NOMOTO AKIO. 小児期発症脊髄性筋萎縮症に対するバルプロ酸ナトリウム多施設共同医師主導治験準備研究血液検体を用いたSMNタンパク質定量解析法. 小児期発症脊髄性筋萎縮症に対するバルプロ酸ナトリウム多施設共同医師主導治験準備研究平成26年度総括・分担研究報告書. 2015. 11-13
AKIYAMA Hiroshi, OTSUKI Noriko. Characteristics of food allergens. The Journal of The Japan Medical Association. 2014. 143. 3. 519-523
OTSUKI Noriko. Prospects for disease treatment of glycyrrhizic acid. 2013. 726. 13-17
AKIYAMA Hiroshi, OTSUKI Noriko. Carotenoid intake and Prevention of the development of food allergies. Functional Food. 2013. 6. 3. 191-197

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Patents (2)：

Method, reagent kit and device for obtaining information regarding spinal muscular atrophy
パパイヤおよび白花蛇舌草の水溶性抽出成分を含む癌の予防、治療または改善のための組成物

Books (1)：

免疫学キーワード辞典第二版
医学書院 2003

Lectures and oral presentations (12)：

脊髄性筋萎縮症(SMA)のバイオマーカー:イメージングフローサイトメトリーを用いたSMNタンパク質解析法の提案
(ルミネックスウェブセミナー 2020)
Improvement of the analysis method that capable of monitoring the level of survival motor neuron (SMN) protein.
(The Japan Society of Human Genetics 2018)
Establishment of the analysis method that capable of monitoring the level of survival motor neuron (SMN) protein.
(The Japanese Society of Gene Diagnosis and Therapy 2018)
The determination of major antigens from cow’s milk in cosmetics and quasi-drug for skin care
(Japanese Society of Food Chemistry 2014)
The Mechanism of Allergy development by Cochineal Dye
(Japanese Society for Food Hygiene and Safety 2013)

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Professional career (1)：

Ph.D. (Tokyo Medical and Dental University)

Awards (1)：

2015 - 日本食品化学学会論文賞化粧品・医薬部外品中の乳アレルゲンタンパク質の分析

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