Rchr

J-GLOBAL ID：200901086284485459 Update date: Nov. 16, 2023

Matsui Tadashi

マツイタダシ | Matsui Tadashi

Affiliation and department：
Job title： Assistant Professor

Research keywords (2)： 53BP1 , 53BP1

Research theme for competitive and other funds (5)：

2020 - 2022 細胞内架橋分子Plectinの放射線誘発DNA損傷応答における新規機能の解明
2015 - 2017 細胞骨格接着分子プレクチンの放射線誘発DNA損傷応答における新規機能の解明
2001 - 2002 C型肝炎ウイルスによる二本鎖RNA依存性プロテインキナーゼの阻害
1999 - 2000 C型肝炎ウィルスNS5A蛋白質のインターフェロン抵抗性、発癌性との関連
1997 - 1998 Three-hybrid法によるC型肝炎ウイルスRNA3'末端結合蛋白質の検索

Papers (42)：

Ryo Sakasai, Tadashi Matsui, Yumi Sunatani, Kuniyoshi Iwabuchi. UbcH5c-dependent activation of DNA-dependent protein kinase in response to replication-mediated DNA double-strand breaks. Biochemical and Biophysical Research Communications. 2023. 668. 42-48
Ryo Sakasai, Mitsuo Wakasugi, Tadashi Matsui, Yumi Sunatani, Masafumi Saijo, Tsukasa Matsunaga, Kuniyoshi Iwabuchi. Camptothecin compromises transcription recovery and cell survival against cisplatin and ultraviolet irradiation regardless of transcription-coupled nucleotide excision repair. DNA repair. 2022. 113. 103318-103318
Yumi.Sunatani, Radhika Pankaj Kamdar, Mukesh Kumar Sharma, Tadashi.Matsui, Ryo.Sakasai, Mitsumasa.Hashimoto, Yasuhito.Ishigaki, Yoshihisa.Matsumoto, Kuniyoshi.Iwabuchi. Caspase-mediated cleavage of X-ray repair cross-complementing group 4 promotes apoptosis by enhancing nuclear translocation of caspase-activated DNase. Experimental cell research. 2018. 362. 2. 450-460
JS.Yoo, K.Takahasi, CS.Ng, R.Ouda, K.Onomoto, M.Yoneyama, JC.Lai, S.Lattmann, Y.nagamine, T.Matsui, et al. DHX36 enhances RIG-I signaling by facilitating PKR-mediated antiviral stress granule formation. PLoS pathogens. 2014. 10:e1004012;1-18
J.Yoshida, K.Iwabuchi, T.Matsui, T.Ishibashi, T.Masuoka, M.Nishio. Knockdown of stromal interaction molecule 1 (STIM1) suppresses store-operated calcium entry, cell proliferation and tumorigenicity in human epidermoid carcinoma A431 cells. Biochemical pharmacology. 2012. 84:1592-1603

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Lectures and oral presentations (74)：

DNA複製を介したDNA二本鎖切断の修復機構とその破綻による核の断片化
(第96回日本生化学会大会 2023)
53BP1- and BRCA2-dependent biphasic repair of replication-mediated one-ended DNA double-strand breaks DNA 複製を介した one-end DNA 二本鎖切断の 53BP1 と BRCA2 による二相性修復
(日本放射線影響学会第65回大会 2022)
Camptothecin compromises transcription recovery and cell survival against cisplatin
(2021)
Top1-DNAクロスリンクによる転写ストレス応答とその破綻
(日本放射線影響学会第63回大会 2020)
Plectinによるp53依存的p21発現の抑制
(第42回日本分子生物学会年会 2019)

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Education (2)：

1991 - 1996 Tokyo Institute of Technology Graduate School Division of Life Science and Engineering
1987 - 1991 Tokyo Institute of Technology Faculty of Science

Professional career (1)：

Doctor(Science)

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