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J-GLOBAL ID：201802246252913737   Reference number：18A0153861

Caspase-mediated cleavage of X-ray repair cross-complementing group 4 promotes apoptosis by enhancing nuclear translocation of caspase-activated DNase

X腺修復架橋相補グループ4のカスパーゼで仲介される切断はカスパーゼ活性化DNアーゼの核への移行を促進することによりアポトーシスを促進する【Powered by NICT】

Author (10)： Sunatani Yumi (Department of Biochemistry I, School of Medicine, Kanazawa Medical University, Kahoku-gun, Ishikawa 920-0293, Japan) ,  Kamdar Radhika Pankaj (Laboratory for Advanced Nuclear Energy, Institute of Innovative Research, Tokyo Institute of Technology, Meguro-ku, Tokyo 152-8550, Japan) ,  Sharma Mukesh Kumar (Laboratory for Advanced Nuclear Energy, Institute of Innovative Research, Tokyo Institute of Technology, Meguro-ku, Tokyo 152-8550, Japan) ,  Sharma Mukesh Kumar (Department of Zoology, SPC Government College, Ajmer, Rajasthan 305001, India) ,  Matsui Tadashi (Department of Biochemistry I, School of Medicine, Kanazawa Medical University, Kahoku-gun, Ishikawa 920-0293, Japan) ,  Sakasai Ryo (Department of Biochemistry I, School of Medicine, Kanazawa Medical University, Kahoku-gun, Ishikawa 920-0293, Japan) ,  Hashimoto Mitsumasa (Department of Physics, General Education Department, Kanazawa Medical University, Kahoku-gun, Ishikawa 920-0293, Japan) ,  Ishigaki Yasuhito (Division of Molecular and Cell Biology, Medical Research Institute, Kanazawa Medical University, Kahoku-gun, Ishikawa 920-0293, Japan) ,  Matsumoto Yoshihisa (Laboratory for Advanced Nuclear Energy, Institute of Innovative Research, Tokyo Institute of Technology, Meguro-ku, Tokyo 152-8550, Japan) ,  Iwabuchi Kuniyoshi (Department of Biochemistry I, School of Medicine, Kanazawa Medical University, Kahoku-gun, Ishikawa 920-0293, Japan)
Material： Experimental Cell Research  (Exp Cell Res)
Volume： 362  Issue： 2  Page： 450-460  Publication year： 2018 
JST Material Number： B0313A  ISSN： 0014-4827  CODEN： ECREAL  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： X-ray repair cross-complementi...

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Thesaurus term： *caspase ,  lymphoma ,  human ,  mRNA ,  DNA double strand break ,  *Apoptosis ,  Proteins ,  phosphorylation ,  wild type ,  antitumor drug ,  protein kinase ,  XRCC4 protein ,  diterpene ,  oxygen heterocyclic compound ,  bridged compound
Semi thesaurus term： 癌治療 ,  阻害剤 , 【Automatic Indexing@JST】

Author keywords (6)： Apoptosis ,  XRCC4 ,  CAD ,  ICAD ,  SRSF1 ,  SRPK1

JST classification (1)： Cell physiology in general  (EF02010S)

Substance index (1)： Paclitaxel

Terms in the title (10)： 修復 ,  架橋 ,  グループ ,  カスパーゼ ,  仲介 ,  カスパーゼ活性化DNアーゼ ,  核 ,  移行 ,  促進 ,  アポトーシス