Yoshimura Yuichi

ヨシムラユウイチ | Yoshimura Yuichi

Affiliation and department：
Job title： Associate Professor
Homepage URL (1)： http://www.tohoku-mpu.ac.jp/laboratory/bunsiya/index.html

Research field (1)： Pharmaceuticals - chemistry and drug development

Research keywords (4)：核酸化学 , 有機合成化学 , 医薬品化学 , Medicinal Chemistry

Research theme for competitive and other funds (9)：

2021 - 2024 Design and synthesis of nucleosides to develop antiviral agents and oligonucleotide therapeutics
2018 - 2021 Synthesis of novel anti-HIV nucleosides aiming at overcoming drug resistance and its application to nucleic acid medicines
2015 - 2018 Development of Nucleic Acid Medicines Based on Synthetic Study of Novel Nucleoside Derivatives
2013 - 2016 Asymmetric syntheses of various iminofuranoses having a side chain at C1 position and their biological evaluation as enzyme inhibitors
2012 - 2015 Synthesis of Nucleoside Derivatives Applicable to Nucleic Acid Medicine

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Papers (98)：

Koichi Narita, Shotaro Yoshida, Hiroka Satoh, Kazuhiro Watanabe, Yuichi Yoshimura. Synthetic route for optically active tetracyclic hexahydrobenzofurobenzopyran skeleton of bisabosquals. Tetrahedron. 2022. 119. 132871-132871
Koichi Narita, Keisuke Suganuma, Toshihiro Murata, Ryutaro Kondo, Hiroka Satoh, Kazuhiro Watanabe, Kenroh Sasaki, Noboru Inoue, Yuichi Yoshimura. Synthesis and evaluation of trypanocidal activity of derivatives of naturally occurring 2,5-diphenyloxazoles. Bioorganic and Medicinal Chemistry. 2021. 42. 116253-116253
Rion Maeda, Noriko Saito-Tarashima, Hideaki Wakamatsu, Yoshihiro Natori, Noriaki Minakawa, Yuichi Yoshimura. Synthesis and Properties of 4′-ThioLNA/BNA. Organic Letters. 2021. 23. 10. 4062-4066
Koichi Narita, Ryuhei Kimura, Hiroka Satoh, Kazuhiro Watanabe, Yuichi Yoshimura. Concise Syntheses of Violaceoids A and C. Chemical and Pharmaceutical Bulletin. 2021. 69. 2. 232-235
Yuichi Yoshimura. Palladium-Catalyzed Three-Component Coupling of Ynamides. Organic Letters. 2020. 22. 14. 5299-5303

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MISC (67)：

成田紘一, 佐藤廣河, 渡邉一弘, 吉村祐一. マレイミド天然物オキサレイミドIの全合成研究. 日本薬学会東北支部大会講演要旨集. 2023. 62nd
成田紘一, 佐藤廣河, 渡邉一弘, 吉村祐一. Synthetic study on maleimide natural product oxaleimide I. 日本薬学会年会要旨集(Web). 2023. 143rd
小野寺のどか, 佐藤陸, 今泉晴喜, 佐藤廣河, 成田紘一, 吉村祐一, 渡邉一弘. Investigation of piperidine ring construction with silver(I) ions. 日本薬学会年会要旨集(Web). 2023. 143rd
渡邉一弘, 佐藤陸, 佐藤廣河, 成田紘一, 吉村祐一. Development of novel piperidine ring construction using silver(I) ion. 日本薬学会年会要旨集(Web). 2022. 142nd
佐藤廣河, 保坂猛成, 成田紘一, 渡邉一弘, 吉村祐一. Schenckエン反応を用いたフェルギネンAおよびBの全合成. 反応と合成の進歩シンポジウム講演要旨集. 2022. 48th

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Patents (17)：

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Books (2)：

無機化合物・錯体ー生物無機化学の基礎ー
廣川書店 2005
Design and New Types of Antitumor Nucleosides : The Synthesis and Antitumor Activity of 2'-Deoxy-(2'-C-substituted)cytidines (共著)
Nucleosides Nucleotides as Antitumor and Antiviral Agents (Plenum Publishing Co. )

Lectures and oral presentations (128)：

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Education (4)：

Professional career (1)：

Work history (9)：

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Awards (1)：

Association Membership(s) (4)：

アメリカ化学会 , 有機合成化学協会 , 日本癌学会 , 日本薬学会

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