Rchr
J-GLOBAL ID:200901087690629433   Update date: Apr. 24, 2023

Yoshimura Yuichi

ヨシムラ ユウイチ | Yoshimura Yuichi
Affiliation and department:
Job title: Associate Professor
Homepage URL  (1): http://www.tohoku-mpu.ac.jp/laboratory/bunsiya/index.html
Research field  (1): Pharmaceuticals - chemistry and drug development
Research keywords  (4): 核酸化学 ,  有機合成化学 ,  医薬品化学 ,  Medicinal Chemistry
Research theme for competitive and other funds  (9):
  • 2021 - 2024 Design and synthesis of nucleosides to develop antiviral agents and oligonucleotide therapeutics
  • 2018 - 2021 Synthesis of novel anti-HIV nucleosides aiming at overcoming drug resistance and its application to nucleic acid medicines
  • 2015 - 2018 Development of Nucleic Acid Medicines Based on Synthetic Study of Novel Nucleoside Derivatives
  • 2013 - 2016 Asymmetric syntheses of various iminofuranoses having a side chain at C1 position and their biological evaluation as enzyme inhibitors
  • 2012 - 2015 Synthesis of Nucleoside Derivatives Applicable to Nucleic Acid Medicine
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Papers (94):
  • Koichi Narita, Shotaro Yoshida, Hiroka Satoh, Kazuhiro Watanabe, Yuichi Yoshimura. Synthetic route for optically active tetracyclic hexahydrobenzofurobenzopyran skeleton of bisabosquals. Tetrahedron. 2022. 119. 132871-132871
  • Koichi Narita, Keisuke Suganuma, Toshihiro Murata, Ryutaro Kondo, Hiroka Satoh, Kazuhiro Watanabe, Kenroh Sasaki, Noboru Inoue, Yuichi Yoshimura. Synthesis and evaluation of trypanocidal activity of derivatives of naturally occurring 2,5-diphenyloxazoles. Bioorganic and Medicinal Chemistry. 2021. 42. 116253-116253
  • Rion Maeda, Noriko Saito-Tarashima, Hideaki Wakamatsu, Yoshihiro Natori, Noriaki Minakawa, Yuichi Yoshimura. Synthesis and Properties of 4′-ThioLNA/BNA. Organic Letters. 2021. 23. 10. 4062-4066
  • Koichi Narita, Ryuhei Kimura, Hiroka Satoh, Kazuhiro Watanabe, Yuichi Yoshimura. Concise Syntheses of Violaceoids A and C. Chemical and Pharmaceutical Bulletin. 2021. 69. 2. 232-235
  • Yuichi Yoshimura. Palladium-Catalyzed Three-Component Coupling of Ynamides. Organic Letters. 2020. 22. 14. 5299-5303
more...
MISC (55):
  • 成田紘一, 菅沼啓輔, 村田敏拓, 近藤龍太郎, 佐藤廣河, 渡邉一弘, 佐々木健郎, 井上昇, 吉村祐一. Synthesis and evaluation of trypanocidal activity of derivatives of naturally occurring 2,5-diphenyloxazoles. 日本薬学会年会要旨集(Web). 2022. 142nd
  • 佐藤廣河, 保坂猛成, 成田紘一, 渡邉一弘, 吉村祐一. Total synthesis of ferruginene A and B using the Schenk-ene reaction. 日本薬学会年会要旨集(Web). 2022. 142nd
  • 遠藤柚季乃, 若松秀章, 伊藤恭平, 名取良浩, 斎藤有香子, 吉村祐一. Synthesis of 4’-Substituted Thymidines by the Selective Transformation of Hydroxymethyl Group. 日本薬学会年会要旨集(Web). 2021. 141st
  • 鈴木郁, 名取良浩, 萬浩太, 若松秀章, 斎藤有香子, 吉村祐一. Development of a method for the synthesis of nitrogen-containing heterocyclic compounds using trivalent hypervalent iodine reagents and (PhSe)2. 日本薬学会年会要旨集(Web). 2021. 141st
  • 佐藤廣河, 成田紘一, 吉村祐一, 渡邉一弘. Synthetic study on anti-cancer agent 9-deoxyxenialactol C. 日本薬学会年会要旨集(Web). 2021. 141st
more...
Patents (17):
Books (2):
  • 無機化合物・錯体ー生物無機化学の基礎ー
    廣川書店 2005
  • Design and New Types of Antitumor Nucleosides : The Synthesis and Antitumor Activity of 2'-Deoxy-(2'-C-substituted)cytidines (共著)
    Nucleosides Nucleotides as Antitumor and Antiviral Agents (Plenum Publishing Co. )
Lectures and oral presentations  (128):
  • 海洋由来ジテルペン系天然物cristaxenicin Aの合成研究
    (日本薬学会年会要旨集(CD-ROM) 2018)
  • 海洋性ジテルペノイド9-デオキシキセニアラクトールCの合成研究
    (日本薬学会年会要旨集(CD-ROM) 2018)
  • パラジウム触媒を用いたイナミドの位置選択的炭素炭素結合形成反応
    (日本薬学会年会要旨集(CD-ROM) 2018)
  • 抗がん活性を有する9-デオキシキセニアラクトールCの合成研究:キセニアラクトール骨格の構築
    (複素環化学討論会講演要旨集 2017)
  • ガングリオシドGM3のアシル鎖構造に基づく新たな自然免疫応答と慢性炎症
    (脂質生化学研究 2017)
more...
Education (4):
  • - 1991 北海道大学大学院 薬学研究科
  • - 1991 Hokkaido University Graduate School, Division of Pharmaceutical Sciences
  • - 1985 Hokkaido University Faculty of Pharmaceutical Sciences
  • - 1985 Hokkaido University Faculty of Pharmaceutical Science
Professional career (1):
  • Ph.D.
Work history (9):
  • 2016/04 - 現在 Tohoku Medical and Pharmaceutical University
  • 2014/04 - 2016/03 東北薬科大学 薬学部 教授
  • 2007/04 - 2014/03 東北薬科大学 薬学部 准教授
  • 2005/04 - 2007/03 東北薬科大学助教授
  • 2004 - 2005 東北薬科大学講師
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Awards (1):
  • 2007 - 佐藤記念国内賞(第31回)
Association Membership(s) (4):
アメリカ化学会 ,  有機合成化学協会 ,  日本癌学会 ,  日本薬学会
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