Chen Guoping

チンコクヘイ | Chen Guoping

Affiliation and department：
Job title： Group Leader
Other affiliations (1)：

University of Tsukuba Subprogram in Materials Science and Engineering Doctoral Program in Engineering Sciences Graduate School of Science and Technology Professor

Homepage URL (1)： https://www.nims.go.jp/research/group/tissue-regeneration-materials/

Research field (3)： Biomaterials , Biomedical engineering , Biochemistry

Research keywords (9)： Biomimetic matrices , Composite biomaterials , Nano-micropattern materials , Biomedical polymers , Regenerative medicine , Scaffold , Tissue engineering , biomaterials , Hyperthermia scaffolds

Research theme for competitive and other funds (19)：

2021 - 2024 Preparation of novel photodynamic therapy using locally injected tissue-adhesive porphyrins
2021 - 2024 Composite scaffolds for programmed control of stem cell proliferation and differentiation
2019 - 2022 Development of multifunctional hybrid porous scaffolds for cancer therapy and tissue engineering
2018 - 2020 Design and preparation of micro-patterned materials to control gene transfection
2016 - 2018 Mechanism analysis of neural stem cell maintenance using an in vitro neural stem cell niche ECM model

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Papers (290)：

Rui Sun, Man Wang, Tianjiao Zeng, Huajian Chen, Toru Yoshitomi, Masaki Takeguchi, Naoki Kawazoe, Yingnan Yang, Guoping Chen. Scaffolds functionalized with matrix metalloproteinase-responsive release of miRNA for synergistic magnetic hyperthermia and sensitizing chemotherapy of drug-tolerant breast cancer. Bioactive Materials. 2025. 44. 205-219
Cheng Zhang, Guangqi An, Yunxin Zhu, Xiang Sun, Guoping Chen, Yingnan Yang. Development of a sunlight adjustable parabolic trough reactor for 24-hour efficient photocatalytic wastewater treatment. Chemical Engineering Journal. 2024. 497. 154582-154582
Xinlong Wang, Yingjun Yang, Yongtao Wang, Chengyu Lu, Xiaohong Hu, Naoki Kawazoe, Yingnan Yang, Guoping Chen. Focal adhesion and actin orientation regulated by cellular geometry determine stem cell differentiation via mechanotransduction. Acta biomaterialia. 2024. 182. 81-92
Rui Sun, Huajian Chen, Man Wang, Toru Yoshitomi, Masaki Takeguchi, Naoki Kawazoe, Yingnan Yang, Guoping Chen. Smart composite scaffold to synchronize magnetic hyperthermia and chemotherapy for efficient breast cancer therapy. Biomaterials. 2024. 307. 122511-122511
Tianjiao Zeng, Huajian Chen, Toru Yoshitomi, Naoki Kawazoe, Yingnan Yang, Guoping Chen. Effect of Hydrogel Stiffness on Chemoresistance of Breast Cancer Cells in 3D Culture. Gels (Basel, Switzerland). 2024. 10. 3

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MISC (293)：

Jing Zheng, Yongtao Wang, Naoki Kawazoe, Guoping Chen. EXPLORING THE EFFECT OF VISCOSITY ON OSTEOGENIC DIFFERENTIATION OF MESENCHYMAL STEM CELLS WITH CONTROLLED CELL MORPHOLOGY. TISSUE ENGINEERING PART A. 2023. 29. 11-12. 1172-1173
陳国平, 陳亜洲, 陳亜洲, 川添直輝. Preparation of Biomimetic Scaffolds for Controlling Stem Cell Differentiation. 日本再生医療学会総会(Web). 2023. 22nd
陳国平, 謝燕, 謝燕, 川添直輝. 3D Cell Culture and Accumulation in Scaffolds with Controlled Pore Structures. 日本再生医療学会総会(Web). 2023. 22nd
古屋欽司, 吉冨徹, 大和田洋平, 大原佑介, 榎本剛史, 馬上頌子, 北口大地, 宮崎貴寛, 土井愛美, 下村治, et al. 外科医が望む直腸マーキングを新規蛍光医療材料で解決する. 日本外科学会定期学術集会(Web). 2023. 123rd
吉冨徹, 小松義希, ドアンヴァン, 黒川宏美, 藤原彩織, 川添直輝, 陳国平, 松井裕史. 組織接着性ポルフィリンを用いた光線過敏症を回避する局所投与型光線力学療法の開発. 日本酸化ストレス学会学術集会プログラム・抄録集. 2023. 76th

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Patents (40)：

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Books (31)：

骨組織再生のための多孔質足場材料技術の新展開 - 薬物徐放化,三次元マイクロパターン化 -
Material Stage 2020
Characterisation and Design of Tissue Scaffolds
Woodhead Publishing 2016
再生医療用足場材料の開発と市場
シーエムシー出版 2016
Encyclopedia of Biomedical Polymers and Polymeric Biomaterials
Taylor & Francis 2016
Polymeric Biomaterials for Tissue Regeneration-From Surface/Interface Design to 3D Constructs
Springer 2016

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Lectures and oral presentations (68)：

Multi-functional Scaffolds of Gold Nanoparticles and Gelatin for Photothermal Therapy and Tissue Engineering
(5th International Symposium of Materials on Regenerative Medicine (ISOMRM2020) 2020)
Development of Porous Scaffolds of Biodegradable Polymers for Regenerative Medicine
(第19回日本再生医療学会総会 2020)
Micropatterned Surfaces for Regulation of Cell Morphology and Functions
(The 18th Asian Chemical Congress 2019)
Bifunctional Composite Scaffolds of Gold Nanoparticles and Gelatin for Photothermal Ablation of Breast Tumor Cells and Adipose Tissue Engineering
(The 19th Asian BioCeramic Symposium (2019ABC) 2019)
Preparation of Gold Nanoparticles with Tunable Size and Morphology for Biomedical Applications
(International Symposium on Gold Chemistry 2018 2019)

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Education (2)：

1994 - 1997 Kyoto University Graduate School of Engineering Department of Material Chemistry
Kyoto University, Graduate School of Engineering, Deportment of Material Chemistry

Professional career (1)：

Doctor of Engineering

Work history (18)：

2023/04 - 現在 National Institute for Materials Science Research Center for Macromolecules and Biomaterials Group Leader
2013/10 - 現在 University of Tsukuba Department of Materials Science and Engineering, Graduate School of Pure and Applied Science Professor (Adjunct)
2017/04 - 2023/03 National Institute for Materials Science Research Center for Functional Materials Group Leader
2016/04 - 2017/03 National Institute for Materials Science International Center for Materials Nanoarchitectonics Field Coordinator and MANA Principal Investigator
2015/04 - 2016/03 National Institute for Materials Science International Center for Materials Nanoarchitectonics Field Coordinator, Unit Director and PI

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Committee career (21)：

2024/01 - 現在 Tissue Engineering and Regenerative Medicine International Society-Asia-Pacific Chapter (TERMIS-AP) Chair Elect
2022/07 - 現在 Materials Horizons Scientific editor
2021/02 - 現在 Exploration Senior Editorial Board Member
2020/07 - 現在 Bioactive Materials Editorial Board
2019/01 - 現在 Journal of Tissue Engineering Editorial Board

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Awards (14)：

2023/10 - Outstanding Scientist Award
2023/10 - Distinguished Member Award
2023/06 - Biomaterials Advances Innovation Award
2020/12 - International Union of Societies for Biomaterials Science and Engineering Fellow Biomaterials Science and Engineering (FBSE)
2018/09 - Romanian Society for Biomaterials SRB Excellence Award Porous Scaffolds with Hybrid and Micropatterned Structures for Tissue Engineering

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Association Membership(s) (5)：

Tissue Engineering and Regenerative Medicine International Society , THE SOCIETY OF POLYMER SCIENCE, JAPAN , THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE , 日本バイオマテリアル学会 , The Japanese Society for Biomaterials

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