Kato Nobuyuki

カトウノブユキ | Kato Nobuyuki

Affiliation and department：
Homepage URL (2)： http://www.okayama-u.ac.jp/user/med/dmb/index.html , http://www.okayama-u.ac.jp/user/med/byobun/index.html

Research field (1)： Virology

Research keywords (4)：分子生物学 , ウィルス学 , Molecular Biology , Virology

Research theme for competitive and other funds (20)：

2016 - 2019 Research on the mechanism of hepatocarcinogenesis by long-term replication of hepatitis virus
2015 - 2017 Antiviral mechanism of new endoperoxide compounds showing antimalarial activity
2013 - 2016 Joint Cooperative Research for Endemic Diseases Control in Ghana
2013 - 2016 Research on host factors which are involved in the progression of HCV-induced hepatic deseases
2012 - 2012 Development ofthe infection and proliferation systemof the 1bgenotype HCV based on the new idea

Show all

Papers (123)：

Hiromichi Dansako, Masanori Ikeda, Yasuo Ariumi, Yosuke Togashi, Nobuyuki Kato. Hepatitis C virus NS5B triggers an MDA5-mediated innate immune response by producing dsRNA without the replication of viral genomes. The FEBS journal. 2023
Hiromichi Dansako, Youki Ueda, Shinya Satoh, Nobuyuki Kato. Extracellular vesicles activate ATM-Chk2 signaling pathway through the intercellular transfer of mitochondrial DNA in HBV-infected human hepatocytes. The FASEB Journal. 2021. 35. 6
Weilin Gu, Youki Ueda, Hiromichi Dansako, Shinya Satoh, Nobuyuki Kato. Antiviral mechanism of preclinical antimalarial compounds possessing multiple antiviral activities. FASEB bioAdvances. 2021. 3. 5. 356-373
Daichi Onomura, Shinya Satoh, Youki Ueda, Hiromichi Dansako, Nobuyuki Kato. Identification of ribavirin-responsive cis-elements for GPAM suppression in the GPAM genome. Biochemical and biophysical research communications. 2020. 533. 1. 148-154
Nobuyuki Kato, Youki Ueda, Hiroe Sejima, Weilin Gu, Shinya Satoh, Hiromichi Dansako, Masanori Ikeda, Kunitada Shimotohno. Study of multiple genetic variations caused by persistent hepatitis C virus replication in long-term cell culture. Archives of virology. 2020. 165. 2. 331-343

ｍore...

MISC (202)：

佐藤伸哉, 小野村大地, 渡士幸一, 上田優輝, 團迫浩方, 本多政夫, 金子周一, 鈴木哲朗, 加藤宣之. Drug screening for suppression of neutral lipid synthesis by targeting C/EBPα. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
Mitsuhiro Machitani, Fuminori Sakurai, Keisaku Wakabayashi, Kosuke Nakatani, Masashi Tachibana, Nobuyuki Kato, Toshiyoshi Fujiwara, Hiroyuki Mizuguchi. Suppression of Oncolytic Adenovirus-Mediated Hepatotoxicity by Liver-Specific Inhibition of NF-κB. Molecular therapy oncolytics. 2017. 7. 76-85
Youki Ueda, Hiromichi Dansako, Shinya Satoh, Hye-Sook Kim, Yusuke Wataya, Hiroyuki Doi, Masanori Ikeda, Nobuyuki Kato. Evaluation of preclinical antimalarial drugs, which can overcome direct acting antivirals-resistant hepatitis C viruses, using the viral reporter assay systems. VIRUS RESEARCH. 2017. 235. 37-48
Shinya Satoh, Kyoko Mori, Daichi Onomura, Youki Ueda, Hiromichi Dansako, Masao Honda, Shuichi Kaneko, Masanori Ikeda, Nobuyuki Kato. Ribavirin suppresses hepatic lipogenesis through inosine monophosphate dehydrogenase inhibition: Involvement of adenosine monophosphate-activated protein kinase-related kinases and retinoid X receptor α. Hepatology Communications. 2017. 1. 6. 550-563
Sayuri Nitta, Yasuhiro Asahina, Mami Matsuda, Norie Yamada, Ryuichi Sugiyama, Takahiro Masaki, Ryosuke Suzuki, Nobuyuki Kato, Mamoru Watanabe, Takaji Wakita, et al. Effects of Resistance-Associated NS5A Mutations in Hepatitis C Virus on Viral Production and Susceptibility to Antiviral Reagents. SCIENTIFIC REPORTS. 2016. 6. 34652

ｍore...

Patents (19)：

新規抗HCV剤
新規抗HCV剤
新規抗HCV剤
新規HCVレプリコン複製細胞および全長HCVRNA複製細胞、ならびにこれらの応用
新規HCVレプリコン複製細胞および全長HCVRNA複製細胞、ならびにこれらの応用

ｍore...

Books (40)：

平成24-26年度厚生労働科学研究費補助金肝炎等克服緊急対策研究事業(肝炎分野)総合研究報告書
肝炎等克服緊急対策研究事業 2015
平成26年度厚生労働科学研究費補助金肝炎等克服緊急対策研究事業(肝炎分野)総括・分担研究報告書
肝炎等克服緊急対策研究事業 2015
平成25年度厚生労働科学研究費補助金B型肝炎創薬実用化等研究事業(肝炎分野)総括・分担研究報告書
B型肝炎創薬実用化等研究事業 2014
平成22-26年度岡山大学大学院医歯薬学総合研究科難治性感染症プロジェクト運営委員会研究報告書
難治性感染症プロジェクト運営委員会 2014
平成25年度岡山大学大学院医歯薬学総合研究科難治性感染症プロジェクト運営委員会研究報告書
難治性感染症プロジェクト運営委員会 2014

ｍore...

Lectures and oral presentations (346)：

交感神経遮断薬であるグアンファシン抗HCV活性機構について
(第40回日本分子生物学会 2017)
Broad antiviral activities of acidic polysaccharides isolated from marine algae
(第65回日本ウイルス学会学術集会 2017)
Guanfacine, a sympatholytic drugs, exhibits anti-hepatitis C virus activity
(第65回日本ウイルス学会学術集会 2017)
Resistant acquisition mechanism for anti-HCV drug candidates,N-89 and its derivative N-251
(第65回日本ウイルス学会学術集会 2017)
Screening of FDA-approved drugs activating cyclic GMP-AMP synthase promoter
(第65回日本ウイルス学会学術集会 2017)

ｍore...

Education (4)：

- 1979 Hokkaido University
- 1979 Hokkaido University Graduate School, Division of Pharmaceutical Sciences
- 1977 Hokkaido University Faculty of Pharmaceutical Sciences
- 1977 Hokkaido University Faculty of Pharmaceutical Science

Professional career (1)：

Pharmaceutical Science (Hokkaido University)

Work history (2)：

2004 - - 岡山大学医歯薬学総合研究科教授
2004 - - Professor,Graduate School of Medicine, Dentistry and Pharmaceutical Sciences,Okayama University

Committee career (1)：

1987 - 日本ウィルス学会評議員

Awards (1)：

1993 - 田宮記念賞

Association Membership(s) (4)：

日本肝臓学会 , 日本ウィルス学会 , 日本癌学会 , 日本分子生物学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page