Art

J-GLOBAL ID：201802220175368545   Reference number：18A0261432

Evaluation of preclinical antimalarial drugs, which can overcome direct-acting antivirals-resistant hepatitis C viruses, using the viral reporter assay systems

ウイルスレポーターアッセイ系を用いた,直接作用抗ウイルス薬抵抗性C型肝炎ウイルスを克服できる,前臨床抗マラリア薬の評価【Powered by NICT】

Author (8)： Ueda Youki (Department of Tumor Virology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan) ,  Dansako Hiromichi (Department of Tumor Virology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan) ,  Satoh Shinya (Department of Tumor Virology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan) ,  Kim Hye-Sook (Division of International Infectious Diseases Control, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan) ,  Wataya Yusuke (Department of Epidemiology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan) ,  Doi Hiroyuki (Department of Epidemiology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan) ,  Ikeda Masanori (Department of Persistent and Oncogenic Viruses, Center for Chronic Viral Diseases, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan) ,  Kato Nobuyuki (Department of Tumor Virology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan)
Material： Virus Research  (Virus Res)
Volume： 235  Page： 37-48  Publication year： 2017 
JST Material Number： A0381D  ISSN： 0168-1702  CODEN： VIREDF  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Abstract/Point： Persistent hepatitis C virus (...

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Thesaurus term： infection ,  patient ,  Drug Resistance ,  chronic hepatitis C ,  therapy ,  *antimalarial drug ,  *hepatitis C virus ,  RNA ,  genome ,  *antiviral drug ,  Amino Acid Substitution ,  NS5B ,  NS3 ,  *microorganism
Semi thesaurus term： 慢性肝疾患 , 【Automatic Indexing@JST】

Author keywords (5)： HCV reporter assay systems ,  Anti-HCV agents ,  DAA-resistant HCVs ,  N-89 ,  N-251

JST classification (2)： Virology in general  (EG04010J) ,  Plant diseases caused by viruses  (FC04054G)

Substance index (1)： Simeprevir

Terms in the title (8)： ウイルス ,  レポーターアッセイ ,  抗ウイルス薬 ,  抵抗性 ,  C型肝炎ウイルス ,  臨床 ,  抗マラリア薬 ,  評価